Molecular Control of Flower Initiation: Rhythms in Redox State as a Basis for Hydro- Electrochemical Signal Transduction

2003 ◽  
Vol 2003 (Spring) ◽  
Author(s):  
Edgar Wagner ◽  
Lars Lehner ◽  
Marcus Garzon ◽  
Johannes Normann ◽  
Jolana T.P. Albrechtova
Keyword(s):  
Signal Transduction ◽  
Redox State ◽  
Flower Initiation ◽  
Molecular Control ◽  
Electrochemical Signal

scholarly journals Tungsten disulfide nanosheets supported poly(xanthurenic acid) as a signal transduction interface for electrochemical genosensing applications

RSC Advances ◽  
2018 ◽  
Vol 8 (69) ◽  
pp. 39703-39709 ◽  
Author(s):  
Jimin Yang ◽  
Xuesong Yin ◽  
Min Xia ◽  
Wei Zhang
Keyword(s):  
Signal Transduction ◽  
Tungsten Disulfide ◽  
Xanthurenic Acid ◽  
Pik3ca Gene ◽  
Electrochemical Signal

An electrochemical signal transduction sensing interface for detecting PIK3CA gene was developed based on WS2 nanosheets supported PXa.

scholarly journals Signal transduction, cell division, differentiation and development: towards unifying mechanisms for pattern formation in plants

2003 ◽  
Vol 15 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Marcelo Carnier Dornelas
Keyword(s):  
Signal Transduction ◽  
Cell Division ◽  
Pattern Formation ◽  
Cell Communication ◽  
Molecular Control ◽  
Form And Function ◽  
Plant Signal Transduction ◽  
Model Plant Arabidopsis Thaliana ◽  
Plant Form ◽  
And Function

The elaboration of plant form and function depends on the ability of a plant cell to divide and differentiate. The decisions of individual cells to enter the cell cycle, maintain proliferation competence, become quiescent, expand, differentiate, or die depend on cell-to-cell communication and on the perception of various signals. These signals can include hormones, nutrients, light, temperature, and internal positional and developmental cues. In recent years, progress has been made in understanding the molecular control of plant pattern formation, especially in the model plant Arabidopsis thaliana. Furthermore, specific genes have been found that are necessary for normal pattern formation and the control of the rates of cell division and differentiation. Cloning of these genes is revealing the molecular basis of plant pattern formation and the key players on plant signal transduction systems.

scholarly journals Anion-Binding-Induced Electrochemical Signal Transduction in Ferrocenylimidazolium: Combined Electrochemical Experimental and Theoretical Investigation

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 238 ◽  
Author(s):  
Tan-Qing Weng ◽  
Yi-Fan Huang ◽  
Lou-Sha Xue ◽  
Jie Cheng ◽  
Shan Jin ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Density Functional Theory ◽  
Dft Calculations ◽  
Theoretical Investigation ◽  
Density Functional ◽  
Anion Binding ◽  
Theoretical Studies ◽  
Functional Theory ◽  
Electrochemical Signal ◽  
Experimental And Theoretical Studies

Five ferrocene alkymethylimidazolium cations 1a–1d and 2 with different alkyl spacer lengths were reinvestigated using voltammetry and density functional theory (DFT) calculations. The voltammetric responses of ligand 2 toward various anions are described in detail. An interesting and unprecedented finding from both experimental and theoretical studies is that coupled electron and intramolecular anion (F−) transfer may be present in these molecules. In addition, it was also observed that, in these studied molecules, the electrostatic attraction interaction toward F− would effectively vanish beyond 1 nm, which was previously reported only for cations.

scholarly journals The uremic retention solute p-cresyl sulfate alters NO signal transduction by alteration of the soluble guanylate cyclase redox state

2009 ◽  
Vol 9 (S1) ◽  
Author(s):  
Björn KI Meijers ◽  
Constanze Meye ◽  
Johannes-Peter Stasch ◽  
Peter Gross ◽  
Pieter Evenepoel
Keyword(s):  
Signal Transduction ◽  
Guanylate Cyclase ◽  
Redox State ◽  
Soluble Guanylate Cyclase

Anion induced binding electrochemical signal transduction in ferrocenyl benzolimidazolium podands

2006 ◽  
Vol 30 (2) ◽  
pp. 266-271 ◽  
Author(s):  
Yan Bai ◽  
Bing-Guang Zhang ◽  
Chun-Ying Duan ◽  
Dong-Bin Dang ◽  
Qing-Jin Meng
Keyword(s):  
Signal Transduction ◽  
Electrochemical Signal

Reactive oxygen species in cell signaling

2000 ◽  
Vol 279 (6) ◽  
pp. L1005-L1028 ◽  
Author(s):  
Victor J. Thannickal ◽  
Barry L. Fanburg
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Signal Transduction ◽  
Plasma Membrane ◽  
Growth Factors ◽  
Redox State ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Cellular Redox ◽  
By Products

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism, primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant capacity, damage to cellular macromolecules such as lipids, protein, and DNA may ensue. Such a state of “oxidative stress” is thought to contribute to the pathogenesis of a number of human diseases including those of the lung. Recent studies have also implicated ROS that are generated by specialized plasma membrane oxidases in normal physiological signaling by growth factors and cytokines. In this review, we examine the evidence for ligand-induced generation of ROS, its cellular sources, and the signaling pathways that are activated. Emerging concepts on the mechanisms of signal transduction by ROS that involve alterations in cellular redox state and oxidative modifications of proteins are also discussed.

scholarly journals Vitamin C Is a Kinase Inhibitor: Dehydroascorbic Acid Inhibits IκBα Kinase β

2004 ◽  
Vol 24 (15) ◽  
pp. 6645-6652 ◽  
Author(s):  
Juan M. Cárcamo ◽  
Alicia Pedraza ◽  
Oriana Bórquez-Ojeda ◽  
Bing Zhang ◽  
Roberto Sanchez ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Vitamin C ◽  
Enzymatic Activity ◽  
Redox State ◽  
Kinase Inhibitor ◽  
Dehydroascorbic Acid ◽  
Molecular Action ◽  
Cellular Signal ◽  
Direct Linkage

ABSTRACT Reactive oxygen species (ROS) are key intermediates in cellular signal transduction pathways whose function may be counterbalanced by antioxidants. Acting as an antioxidant, ascorbic acid (AA) donates two electrons and becomes oxidized to dehydroascorbic acid (DHA). We discovered that DHA directly inhibits IκBα kinase β (IKKβ) and IKKα enzymatic activity in vitro, whereas AA did not have this effect. When cells were loaded with AA and induced to generate DHA by oxidative stress in cells expressing a constitutive active IKKβ, NF-κB activation was inhibited. Our results identify a dual molecular action of vitamin C in signal transduction and provide a direct linkage between the redox state of vitamin C and NF-κB signaling events. AA quenches ROS intermediates involved in the activation of NF-κB and is oxidized to DHA, which directly inhibits IKKβ and IKKα enzymatic activity. These findings define a function for vitamin C in signal transduction other than as an antioxidant and mechanistically illuminate how vitamin C down-modulates NF-κB signaling.

Sign in / Sign up

Export Citation Format

Share Document