scholarly journals Tribute to R. G. Boutilier: Evidence of a high activity carbonic anhydrase isozyme in the red blood cells of an ancient vertebrate, the sea lamprey Petromyzon marinus

2006 ◽  
Vol 209 (7) ◽  
pp. 1169-1178 ◽  
Author(s):  
A. J. Esbaugh
Keyword(s):  
Carbonic Anhydrase ◽  
Red Blood Cells ◽  
High Activity ◽  
Blood Cells ◽  
Petromyzon Marinus ◽  
Sea Lamprey ◽  
Carbonic Anhydrase Isozyme

Haemocytology of the supraneural myeloid body in the sea lamprey during several phases of life cycle

1974 ◽  
Vol 52 (12) ◽  
pp. 1585-1589 ◽  
Author(s):  
J. C. George ◽  
F. W. H. Beamish
Keyword(s):  
Blood Cells ◽  
Petromyzon Marinus ◽  
Cell Types ◽  
Sea Lamprey ◽  
Histochemical Staining ◽  
Fat Cells ◽  
Cell Type ◽  
Adult Tissue ◽  
Spawning Run ◽  
Early Phases

The supraneural myeloid body of the sea lamprey (Petromyzon marinus) was studied in the feeding adult, late spawning run adult, and metamorphosing ammocoete. The fatty nature of the tissue was established by histochemical staining and electron microscopy. The presence of the fat cells and the actively differentiating blood cells evinced its similarity to the bone marrow in higher animals, thereby suggesting a phylogenetic affinity. In the late spawning run lampreys, the tissue was found to be almost empty of blood cells, leaving empty spaces within the stromal skeleton. In the feeding adult tissue, the various blood cell types differentiated from precursor cells have been identified. Megakaryoblasts possibly representing early phases of the cell type were observed only in the transforming (macrophthalmia stage) and adult lampreys. A marked active development of the tissue in the ammocoete was seen only at the fourth stage of the metamorphosing ammocoete immediately before macrophthalmia. At the macrophthalmia stage, the haematopoietic activity in the tissue increased substantially.

Adenosine causes cAMP-dependent activation of chick embryo red cell carbonic anhydrase and 2,3-DPG synthesis

1996 ◽  
Vol 271 (4) ◽  
pp. R973-R981 ◽  
Author(s):  
S. Glombitza ◽  
S. Dragon ◽  
M. Berghammer ◽  
M. Pannermayr ◽  
R. Baumann
Keyword(s):  
Carbonic Anhydrase ◽  
Red Blood Cells ◽  
Adenylyl Cyclase ◽  
Adenosine Receptor ◽  
Blood Cells ◽  
Cell Protein ◽  
Red Cell ◽  
Receptor Stimulation ◽  
2,3 Dpg ◽  
Stimulation Of

In late chick embryos, coordinate activation of red cell carbonic anhydrase II (CAII) and 2,3-diphosphoglycerate (2,3-DPG) synthesis is initiated by hypoxia. The effects are mediated by unidentified hormonal effectors resident in chick plasma. In the present investigation, we have analyzed the effect of adenosine receptor stimulation on embryonic red cell CAII and 2,3-DPG synthesis. We find that primitive and definitive embryonic red blood cells from chick have an A2a adenosine receptor. Stimulation of the receptor with metabolically stable adenosine analogues causes a large increase of red cell adenosine 3',5'-cyclic monophosphate (cAMP) and subsequent activation of red cell CAII and 2,3-DPG production in definitive red blood cells and of CAII synthesis in primitive red blood cells. Direct stimulation of adenylyl cyclase with forskolin has the same effect. Analysis of red cell protein pattern after labeling with [35S]methionine shows that stimulation of red cell cAMP levels activates synthesis of several other proteins aside from CAII. Presence of actinomycin D inhibits cAMP-dependent changes of protein synthesis, indicating that cAMP-dependent transcriptional activation is required. In contrast to the stable adenosine receptor analogues, adenosine itself was a very weak agonist, unless its metabolism was significantly inhibited. Thus, besides adenosine, other effectors of the adenylyl cyclase system are likely to be involved in the O2 pressure-dependent regulation of red cell metabolism in late development of avian embryos.

Conserved High Activity Binding Peptides are Involved in Adhesion of Two Detergent-Resistant Membrane-Associated Merozoite Proteins to Red Blood Cells during Invasion

2010 ◽  
Vol 53 (10) ◽  
pp. 3907-3918 ◽  
Author(s):  
Ana Zuleima Obando-Martinez ◽  
Hernando Curtidor ◽  
Gabriela Arévalo-Pinzón ◽  
Magnolia Vanegas ◽  
Carolina Vizcaino ◽  
...  
Keyword(s):  
Red Blood Cells ◽  
High Activity ◽  
Blood Cells ◽  
Binding Peptides ◽  
Detergent Resistant Membrane

IgM Natural Autoantibodies Against Bromelain-Treated Mouse Red Blood Cells Recognise Carbonic Anhydrase

Autoimmunity ◽  
1991 ◽  
Vol 9 (3) ◽  
pp. 207-216 ◽  
Author(s):  
A. M. Jonusysj ◽  
K. O. Cox ◽  
E. J. Steele
Keyword(s):  
Carbonic Anhydrase ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Treated Mouse ◽  
Natural Autoantibodies
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