scholarly journals The Nutrition of the Central Nervous System in the Cockroach Periplaneta Americana L

1960 ◽  
Vol 37 (3) ◽  
pp. 500-512
Author(s):  
V. B. WIGGLESWORTH
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Plasma Membrane ◽  
Glial Cell ◽  
Glial Cells ◽  
Periplaneta Americana ◽  
Ganglion Cells ◽  
Cell Layer ◽  
Abdominal Ganglion ◽  
The Central Nervous System

1. The histology of the last abdominal ganglion and the cercal nerves and connectives of the cockroach are briefly described. Attention is called to the large cavities, termed the ‘glial lacunar system’, that are present in the glial cell layer of the ganglion; and to the branching filaments of collagen-like material which are laid down within the glial membranes and trabeculae of the ganglia and nerves. 2. Glycogen is stored in large amounts in the perineurium cells, and in small amounts in the interaxonal glial membranes in the neuropile and nerves. Invaginations of the plasma membrane of the large ganglion cells (the ‘trophospongium’) are apparently concerned in the transfer of glycogen. Invaginations and glycogen deposits increase progressively towards the base of the axon. 3. Very small amounts of triglycerides are stored in the ganglion. There are traces only in the perineurium cells; rather more in the glial cells. The invaginations of the glial cells into the large ganglion cells seem to be concerned also in the transfer of lipids to the neurones.

Some fly sensory organs are gliogenic and require glide/gcm in a precursor that divides symmetrically and produces glial cells

Development ◽  
2000 ◽  
Vol 127 (17) ◽  
pp. 3735-3743 ◽  
Author(s):  
V. Van De Bor ◽  
R. Walther ◽  
A. Giangrande
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Peripheral Nervous System ◽  
Glial Cell ◽  
Glial Cells ◽  
Sensory Organ ◽  
Asymmetric Distribution ◽  
Sensory Organs ◽  
The Central Nervous System ◽  
Glial Precursor

In flies, the choice between neuronal and glial fates depends on the asymmetric division of multipotent precursors, the neuroglioblast of the central nervous system and the IIb precursor of the sensory organ lineage. In the central nervous system, the choice between the two fates requires asymmetric distribution of the glial cell deficient/glial cell missing (glide/gcm) RNA in the neuroglioblast. Preferential accumulation of the transcript in one of the daughter cells results in the activation of the glial fate in that cell, which becomes a glial precursor. Here we show that glide/gcm is necessary to induce glial differentiation in the peripheral nervous system. We also present evidence that glide/gcm RNA is not necessary to induce the fate choice in the peripheral multipotent precursor. Indeed, glide/gcm RNA and protein are first detected in one daughter of IIb but not in IIb itself. Thus, glide/gcm is required in both central and peripheral glial cells, but its regulation is context dependent. Strikingly, we have found that only subsets of sensory organs are gliogenic and express glide/gcm. The ability to produce glial cells depends on fixed, lineage related, cues and not on stochastic decisions. Finally, we show that after glide/gcm expression has ceased, the IIb daughter migrates and divides symmetrically to produce several mature glial cells. Thus, the glide/gcm-expressing cell, also called the fifth cell of the sensory organ, is indeed a glial precursor. This is the first reported case of symmetric division in the sensory organ lineage. These data indicate that the organization of the fly peripheral nervous system is more complex than previously thought.

Studies of Cardio-Regulation in the Cockroach, Periplaneta Americana

1971 ◽  
Vol 54 (2) ◽  
pp. 329-350
Author(s):  
T. MILLER ◽  
P. N. R. USHERWOOD
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Heart Muscle ◽  
Periplaneta Americana ◽  
Ganglion Cells ◽  
Muscle Fibres ◽  
Cardiac Ganglion ◽  
Cardiac Nerve ◽  
The Central Nervous System ◽  
Nerve Cords

1. The heart of Periplaneta americana is segmentally innervated from the central nervous system by three types of neurone. Two of these types of neurones are neurosecretory; one type contains large granules, the other small granules. The segmental nerves are paired structures which join paired lateral cardiac nerve cords. Both types of neurosecretory neurone liberate their contents in the lateral cardiac nerve cords. The neurones with the small granules also synapse with the myocardium as well as with intrinsic cardiac neurones in the lateral cardiac nerve cords. The third type of neurone from the central nervous system is an ordinary efferent neurone and it synapses with the cardiac ganglion cells. 2. A heart chamber is associated with about six cardiac ganglion cells, three on either side. These send processes up and down the lateral cardiac nerve cord and make synaptic contact with the myocardium. 3. The myocardium is multiterminally and polyneuronally innervated, and electrical coupling between muscle fibres appears to be the rule. The fibres are spontaneously active and generate spike-like electrically excited responses. The timing of the electrically excited responses is influenced by the input from the cardiac ganglion cells which evoke a burst of synaptic potentials during diastole. 4. Control of the cockroach heart appears to be organized on three levels. The basic rhythm is myogenic. The timing of the contractions is influenced by inputs from the intrinsic cardiac ganglion cells possibly via a feedback mechanism involving the contractions of the heart muscle. Finally, the activities of the heart muscle and the cardiac ganglion cells are influenced by inputs from the central nervous system.

Neural Stem Cells to Glial Cells an Important Factor for Brain Injury

2020 ◽  
Author(s):  
Prithiv K R Kumar
Keyword(s):  
Stem Cells ◽  
Central Nervous System ◽  
Nervous System ◽  
Neural Stem Cells ◽  
Glial Cells ◽  
Brain Injuries ◽  
The Body ◽  
The Central Nervous System ◽  
Near Future

Stem cells have the capacity to differentiate into any type of cell or organ. Stems cell originate from any part of the body, including the brain. Brain cells or rather neural stem cells have the capacitive advantage of differentiating into the central nervous system leading to the formation of neurons and glial cells. Neural stem cells should have a source by editing DNA, or by mixings chemical enzymes of iPSCs. By this method, a limitless number of neuron stem cells can be obtained. Increase in supply of NSCs help in repairing glial cells which in-turn heal the central nervous system. Generally, brain injuries cause motor and sensory deficits leading to stroke. With all trials from novel therapeutic methods to enhanced rehabilitation time, the economy and quality of life is suppressed. Only PSCs have proven effective for grafting cells into NSCs. Neurons derived from stem cells is the only challenge that limits in-vitro usage in the near future.

scholarly journals Rapid multi-directed cholinergic transmission in the central nervous system

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Santhosh Sethuramanujam ◽  
Akihiro Matsumoto ◽  
Geoff deRosenroll ◽  
Benjamin Murphy-Baum ◽  
J Michael McIntosh ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ganglion Cells ◽  
Release Site ◽  
Amacrine Cells ◽  
Global Scale ◽  
Cholinergic Transmission ◽  
Data Set ◽  
The Central Nervous System ◽  
Synaptic Mechanisms

AbstractIn many parts of the central nervous system, including the retina, it is unclear whether cholinergic transmission is mediated by rapid, point-to-point synaptic mechanisms, or slower, broad-scale ‘non-synaptic’ mechanisms. Here, we characterized the ultrastructural features of cholinergic connections between direction-selective starburst amacrine cells and downstream ganglion cells in an existing serial electron microscopy data set, as well as their functional properties using electrophysiology and two-photon acetylcholine (ACh) imaging. Correlative results demonstrate that a ‘tripartite’ structure facilitates a ‘multi-directed’ form of transmission, in which ACh released from a single vesicle rapidly (~1 ms) co-activates receptors expressed in multiple neurons located within ~1 µm of the release site. Cholinergic signals are direction-selective at a local, but not global scale, and facilitate the transfer of information from starburst to ganglion cell dendrites. These results suggest a distinct operational framework for cholinergic signaling that bears the hallmarks of synaptic and non-synaptic forms of transmission.

Glioblastoma Multiforme with Hypodipsic Hypernatremia in a Seven-Month-Old Golden Retriever

2016 ◽  
Vol 52 (5) ◽  
pp. 319-324 ◽  
Author(s):  
Stephanie Engel ◽  
Karen Marie Hilling ◽  
Travis Kuder Meuten ◽  
Chad Brendan Frank ◽  
Angela J. Marolf
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Glioblastoma Multiforme ◽  
Glial Cell ◽  
Congenital Malformations ◽  
Cell Tumor ◽  
Golden Retriever ◽  
Neoplastic Process ◽  
Underlying Causes ◽  
The Central Nervous System

ABSTRACT Primary hypodipsic hypernatremia is a rarely reported disease in dogs. Reported underlying causes associated with this disease in dogs include congenital malformations, encephalitis, intracranial neoplasia, and pressure atrophy of the hypothalamus secondary to hydrocephalus. The dog in this report had an infiltrative neoplastic disorder, likely causing damage to the hypothalamic osmoreceptors responsible for the thirst generation. The neoplastic process was identified histopathologically as glioblastoma multiforme, an unusual tumor to occur in a dog this young. A tumor of the central nervous system causing physical destruction of the osmoreceptors has rarely been reported in dogs and none of the previously reported cases involved a glial cell tumor.

Radioautographic evidence for the protracted proliferation of glial cells in the central nervous system of jimpy mice

1981 ◽  
Vol 2 (3) ◽  
pp. 411-416 ◽  
Author(s):  
A. Privat ◽  
J. Valat ◽  
F. Lachapelle ◽  
N. Baumann ◽  
J. Fulcrand
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Glial Cells ◽  
The Central Nervous System ◽  
Jimpy Mice

Sodium and Potassium Fluxes in the Abdominal Nerve Cord of the Cockroach, Periplaneta Americana L

1961 ◽  
Vol 38 (2) ◽  
pp. 315-322
Author(s):  
J. E. TREHERNE
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Nerve Cord ◽  
Periplaneta Americana ◽  
Unit Area ◽  
Potassium Ions ◽  
Sodium Ions ◽  
Nerve Sheath ◽  
The Central Nervous System ◽  
Sodium And Potassium

1. The influx of sodium and potassium ions into the central nervous system of Periplaneta americana has been studied by measuring the increase in radioactivity within the abdominal nerve cord following the injection of 24NA and 42K. into the haemolymph. 2. The calculated influx of sodium ions was approximately 320 mM./l. of nerve cord water/hr. and of potassium ions was 312 mM./l. of nerve cord water/hr. These values are very approximately equivalent to an influx per unit area of nerve cord surface of 13.9 x 10-2 M cm. -2 sec.-1 for sodium and 13.5 x 10-12 M cm. -2 sec.-1 for potassium ions. 3. The relatively rapid influxes of these ions are discussed in relation to the postulated function of the nerve sheath as a diffusion barrier. It is suggested that a dynamic steady state rather than a static impermeability must exist across the sheath surrounding the central nervous system in this insect.

The development of central nervous system control of the gill withdrawal reflex evoked by siphon stimulation in Aplysia

1979 ◽  
Vol 57 (9) ◽  
pp. 987-997 ◽  
Author(s):  
Ken Lukowiak
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Abdominal Ganglion ◽  
System Control ◽  
Reflex Amplitude ◽  
Withdrawal Reflex ◽  
Reflex Latency ◽  
Neural Processes ◽  
The Central Nervous System ◽  
Cns Control

In older Aplysia, the central nervous system (CNS) (abdominal ganglion) exerts suppressive and facilitatory control over the peripheral nervous system (PNS) which initially mediates the gill withdrawal reflex and its subsequent habituation evoked by tactile stimulation of the siphon. In young animals, both the suppressive and facilitatory CNS control were found to be absent. In older animals, removal of branchial nerve (Br) input to the gill resulted in a significantly reduced reflex latency and, with ctenidial (Ct) and siphon (Sn) nerves intact, a significantly increased reflex amplitude and an inability of the reflex to habituate with repeated siphon stimulation. In young animals, removal of Br had no effect on reflex latency and with Ct and Sn intact, the reflex amplitude latency was not increased and the reflex habituated. Older animals can easily discriminate between different intensity stimuli applied to the siphon as evidenced by differences in reflex amplitude, rates of habituation, and evoked neural activity. On the other hand, young animals cannot discriminate well between different stimulus intensities. The lack of CNS control in young animals was found to be due to incompletely developed neural processes within the abdominal ganglion and not the PNS. The lack of CNS control in young Aplysia results in gill reflex behaviours being less adaptive in light of changing stimulus conditions, but may be of positive survival value in that the young will not habituate as easily. The fact that CNS control is present in older animals strengthens the idea that in any analysis of the underlying neural mechanisms of habituation the entire integrated CNS–PNS must be taken into account.

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