Dietary Protease Supplementation Attenuates Eccentric-exercise Induced Force Production Decrements By Regulating Leukocyte Activity

Catechins have a great variety of biological actions. We evaluated the potential benefits of catechin ingestion on muscle contractile properties, oxidative stress, and inflammation following downhill running, which is a typical eccentric exercise, in senescence-accelerated prone mice (SAMP). Downhill running (13 m/min for 60 min; 16° decline) induced a greater decrease in the contractile force of soleus muscle and in Ca2+-ATPase activity in SAMP1 compared with the senescence-resistant mice (SAMR1). Moreover, compared with SAMR1, SAMP1 showed greater downhill running-induced increases in plasma CPK and LDH activity, malondialdehyde, and carbonylated protein as markers of oxidative stress; and in protein and mRNA expression levels of the inflammatory mediators such as tumor necrosis factor-α and monocyte chemoattractant protein-1 in muscle. SAMP1 exhibited aging-associated vulnerability to oxidative stress and inflammation in muscle induced by downhill running. Long-term (8 wk) catechin ingestion significantly attenuated the downhill running-induced decrease in muscle force and the increased inflammatory mediators in both plasma and gastrocnemius muscle. Furthermore, catechins significantly inhibited the increase in oxidative stress markers immediately after downhill running, accompanied by an increase in glutathione reductase activity. These findings suggest that long-term catechin ingestion attenuates the aging-associated loss of force production, oxidative stress, and inflammation in muscle after exercise.

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Continuous Compression as an Effective Therapeutic Intervention in Treating Eccentric-Exercise-Induced Muscle Soreness

Journal of Sport Rehabilitation ◽

10.1123/jsr.10.1.11 ◽

2001 ◽

Vol 10 (1) ◽

pp. 11-23 ◽

Cited By ~ 55

Author(s):

William J. Kraemer ◽

Jill A. Bush ◽

Robbin B. Wickham ◽

Craig R. Denegar ◽

Ana L. Gomez ◽

...

Keyword(s):

Eccentric Exercise ◽

Sports Medicine ◽

Muscle Soreness ◽

Tissue Injury ◽

Soft Tissue Injury ◽

Force Production ◽

Elbow Flexion ◽

Control Group ◽

Arm Circumference ◽

Exercise Induced

Context:Prior investigations using ice, massage, or exercise have not shown efficacy in relieving delayed-onset muscle soreness.Objectives:To determine whether a compression sleeve worn immediately after maximal eccentric exercise enhances recovery.Design:Randomized, controlled clinical study.Setting:University sports medicine laboratory.Participants:Fifteen healthy, non-strength-trained men, matched for physical criteria, randomly placed in a control group or a continuous compression-sleeve group (CS).Methods and Measures:Subjects performed 2 sets of 50 arm curls. 1RM elbow flexion at 60°/s, upper-arm circumference, resting-elbow angle, serum creatine kinase (CK), and perception-of-soreness data were collected before exercise and for 3 days.Results:CK was significantly (P< .05) elevated from the baseline value in both groups, although the elevation in the CS group was less. CS prevented loss of elbow extension, decreased subjects’ perception of soreness, reduced swelling, and promoted recovery of force production.Conclusions:Compression is important in soft-tissue-injury management.

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308 UNWEIGHTING INCREASES ECCENTRIC EXERCISE-INDUCED MUSCLE DYSFUNCTION AND DAMAGE

Medicine & Science in Sports & Exercise ◽

10.1249/00005768-199405001-00309 ◽

1994 ◽

Vol 26 (Supplement) ◽

pp. S55 ◽

Cited By ~ 1

Author(s):

L Ploutz-Snyder ◽

P Tesch ◽

G Dudley

Keyword(s):

Eccentric Exercise ◽

Muscle Dysfunction ◽

Exercise Induced

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Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

Journal of Pain Research ◽

10.2147/jpr.s139615 ◽

2017 ◽

Vol Volume 10 ◽

pp. 2213-2221 ◽

Cited By ~ 3

Author(s):

Samar Nausheen ◽

Jamal Ali Moiz ◽

Shahid Raza ◽

Mohammed Yakub Shareef ◽

Shahnawaz Anwer ◽

...

Keyword(s):

Muscle Damage ◽

Laser Therapy ◽

Eccentric Exercise ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Light Load ◽

Level Laser ◽

Exercise Induced

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Eccentric exercise-induced muscle damage of pre-adolescent and adolescent boys in comparison to young men

European Journal of Applied Physiology ◽

10.1007/s00421-014-2848-3 ◽

2014 ◽

Vol 114 (6) ◽

pp. 1183-1195 ◽

Cited By ~ 26

Author(s):

Trevor C. Chen ◽

Hsin-Lian Chen ◽

Yi-Chuen Liu ◽

Kazunori Nosaka

Keyword(s):

Muscle Damage ◽

Eccentric Exercise ◽

Young Men ◽

Adolescent Boys ◽

Exercise Induced

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Resistance-Trained Individuals Are Less Susceptible to Oxidative Damage after Eccentric Exercise

Oxidative Medicine and Cellular Longevity ◽

10.1155/2018/6857190 ◽

2018 ◽

Vol 2018 ◽

pp. 1-11 ◽

Cited By ~ 3

Author(s):

Ypatios Spanidis ◽

Dimitrios Stagos ◽

Christina Papanikolaou ◽

Konstantina Karatza ◽

Andria Theodosi ◽

...

Keyword(s):

Oxidative Damage ◽

Eccentric Exercise ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Reducing Power ◽

Protein Carbonyls ◽

Oxidation Reduction ◽

Oxidation Reduction Potential ◽

Exercise Induced ◽

Training Background

It has been proposed that exercise-induced oxidative stress and adaptations are dependent on training status. In this study, we examined the effects of training background on free radical generation and adaptations after eccentric exercise. Forty volunteers were divided into two groups (trained and untrained) and were asked to perform eccentric exercise. Then, their blood samples were collected pre, 24, 48, and 72 hours postexercise. Biomarkers indicating oxidative damage and the antioxidant profiles of the participants were measured in plasma and erythrocyte lysate both spectrophotometrically and chromatographically. The results revealed that the untrained group depicted more severe oxidative damage (protein carbonyls, malondialdehyde), weaker antioxidant status (reduced glutathione, static and capacity oxidation-reduction potential), and weaker radical-scavenging activity (superoxide radical scavenging and reducing power) compared to the trained participants. Our findings show that trained individuals are less susceptible to oxidative damage and suggest that generalized nutritional recommendations regarding recovery after exercise should be avoided.

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