scholarly journals Long-Term Myocardial Damage in Peripartum Cardiomyopathy Associated With Myocarditis

2019 ◽  
Vol 83 (12) ◽  
pp. 2569
Author(s):  
Hiroaki Kawano ◽  
Tomayoshi Hayashi ◽  
Yuji Koide ◽  
Koji Maemura
Keyword(s):  
Myocardial Damage ◽  
Peripartum Cardiomyopathy

scholarly journals Unusual and severe peripartum cardiomyopathy: A case report

2021 ◽  
Vol 6 (2) ◽  
pp. 040-043
Author(s):  
B Lamanna ◽  
M Vinciguerra ◽  
FM Crupano ◽  
R Cicinelli ◽  
E Cicinelli ◽  
...  
Keyword(s):  
Cardiac Disease ◽  
Viral Myocarditis ◽  
Myocardial Damage ◽  
Maculopapular Rash ◽  
Peripartum Cardiomyopathy ◽  
Clinical Context ◽  
Reduced Ejection Fraction ◽  
Abnormal Immune Response ◽  
Long Term Prognosis

Peripartum cardiomyopathy (PPCM) is a relatively rare cardiac disease that manifests in the final stage of pregnancy and in the first months after delivery in women with no preexisting heart disease. Many etiological processes have been suggested: viral myocarditis, abnormal immune response to pregnancy, excessive prolactin excretion, prolonged tocolysis and a familiar predisposition to PPCM. Its diagnosis is often delayed because its symptoms, which include fatigue, dyspnea and palpitations are nonspecific. For this reason the diagnosis of PPCM is still made by exclusion of other etiologies. The long-term prognosis, once the acute phase is over, is a function of myocardial damage, this varies from complete functional recovery to chronic HF. The outcome of PPCM is highly variable with an alevated risk of fetomaternal morbidity and mortality. We report a serious case of a 40 years old female with biamniotic bicorionic twin pregnancy (PMA) who delivered by caesarean section and developed acute PPCM on post-operative. Symptoms occurred two hours after an intramuscular injection of two vials of methylergonovine the same day of cesarean delivery. These manifested in sudden tachypnoe, tachycardia and the appearance itchy maculopapular rash on her chest. On further evaluation, ECHO revealed cardiomegaly with reduced ejection fraction (< 15%). The case was successfully managed by a multidisciplinary team, using drugs like levosimendan and cabergoline, which rapresent emerging strategy in this clinical context.

Long-Term Outcomes in Patients With Peripartum Cardiomyopathy and No Recovery of Ventricular Function

2010 ◽  
Vol 16 (8) ◽  
pp. S97 ◽  
Author(s):  
Kismet D. Rasmusson ◽  
Deborah Budge ◽  
Rami Alharethi ◽  
Kimberly D. Brunisholz ◽  
Jenny J. Connolly ◽  
...  
Keyword(s):  
Ventricular Function ◽  
Peripartum Cardiomyopathy ◽  
Long Term Outcomes

UPDATE ON CARDIOVASCULAR IMPLICATIONS OF COVID 19

2021 ◽  
pp. 238-242
Author(s):  
Pradeep Kumar Radhakrishnan ◽  
Gayathri Ananyajyothi Ambat ◽  
Roshini Ambat ◽  
Syed Ilas Basha ◽  
Hema Prakash ◽  
...  
Keyword(s):  
Virus Disease ◽  
Systemic Vasculitis ◽  
Myocardial Damage ◽  
Viral Disease ◽  
Cardiac Damage ◽  
Corona Virus ◽  
Global Pandemic ◽  
Acute Myocardial Injury ◽  
Exercise Induced

On March 11 2020 WHO declares corona viral disease as a global pandemic .COVID 19 pandemic has taken the world by storm and many countries like India is now experiencing a second surge due to mutant strains. Global health emergency has been precipitated by this corona virus disease caused by SARS CoV2.Acute and intermediate effects on cardiovascular system are becoming obvious with progression of time. SARS-CoV-2-related endothelial dysfunction results in an augmented risk for venous thromboembolism, systemic vasculitis, endothelial cell apoptosis, and inammation in various organs. Acute infections have troponin elevation more due to indirect cardiac damage though denite patterns of direct damage do exist. Intermediate evaluation in patients with resolved infections shows increased incidence of exercise induced arrhythmias and residual cardiovascular symptoms. The virus with its zoonotic origin based upon its genomic identity to bat derived SARS corona virus has a human to human transmission mode.ACE 2 receptors facilitate cellular entry and has been implicated in direct and indirect myocardial damage. Myocarditis, acute myocardial injury, arrhythmias and thromboembolism dominates the clinical picture. Role of imaging must be dened in relation to relevant clinical ndings. With arrival of vaccine and widespread vaccination global programs, we can look forward to understanding and managing long term complications of this disease. Prognostic implications of a resolved disease need to be evaluated by future studies.

scholarly journals Myocardial Damage in an Elderly Female Patient With Peripartum Cardiomyopathy

2021 ◽  
Author(s):  
Hiroaki Kawano ◽  
Kazuki Matsumura ◽  
Eijun Sueyoshi ◽  
Seiji Koga ◽  
Satoshi Ikeda ◽  
...  
Keyword(s):  
Female Patient ◽  
Myocardial Damage ◽  
Peripartum Cardiomyopathy ◽  
Elderly Female

scholarly journals Intramyocardial Hemorrhage Assessed by T2* Imaging is Associated with Myocardial Damage and May Predicts Long-Term Outcome in Patients with Acs

2016 ◽  
Vol 22 (9) ◽  
pp. S177
Author(s):  
Hikaru Hatashima ◽  
Toshiaki Kadokami ◽  
Soichiro Kashihara ◽  
Takayuki Toyohara ◽  
Yasuhiro Sedutsu ◽  
...  
Keyword(s):  
Myocardial Damage ◽  
Term Outcome ◽  
Long Term Outcome

Abstract 2008: Impact of Hyperglycemia on Myocardial Damage and its Prognostic Implications in Patients with Acute ST-Segment Elevation Myocardial Infarction (STEMI) Assessed by Contrast-Enhanced Cardiac Magnetic Resonance Imaging (CMR)

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Christoph J Jensen ◽  
Markus Jochims ◽  
Kai Nassenstein ◽  
Michael Bell ◽  
Thomas Schlosser ◽  
...  
Keyword(s):  
Logistic Regression Model ◽  
Microvascular Obstruction ◽  
Myocardial Damage ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Glucose Levels ◽  
Contrast Enhanced ◽  
Lv Mass ◽  
The Impact

To investigate the impact of admission glucose levels on myocardial damage and long term outcome in patients with acute STEMI using contrast-enhanced CMR. 130 consecutive patients (104 males; mean age 59.4±11.8 years) with first reperfused STEMI were included. Hyperglycemia was defined as glucose levels above 7.8mmol/l. CMR was performed within 3.9±2.2 days after admission on a 1.5 Tesla MR System. The imaging protocol included SSFP cine sequences for the calculation of LV function, volumes and mass. Total no reflow volumes (NRV) and delayed enhancement volumes (DEV) were calculated from planimetry of the IR-SSFP stacks of short axis images by disc-summation performed early / late following administration of 0.2mmol/kg/BW of gadodiamid. NRV and DEV were expressed as percent of LV Mass (NR%, DE%). Continuous variables were compared by Mann-Whitney test. Correlation of admission hyperglycemia and NR% was tested by spearman rank test. Patients were prospectively followed for 30±9 months. A stepwise logistic regression model was used to analyze the impact of hyperglycemia and CMR parameters on NR% and outcome. 55 of 130 (42%) patients had hyperglycemia on admission. Patients with admission hyperglycemia had lower LV ejection fraction (38.6±12.9% vs. 47.7±11.9%, p=0.001), greater ESV (89.2±39.2ml vs. 71.7±34.1ml, p=0.002), greater LV Mass (156.7±40.4g vs. 136.3±36.7g, p=0.003), larger DE% (19.3±13.8% vs. 9.7±8.5%, p<0.001) and larger NR% (8.1± 9.2% vs. 2.3± 4.2%, p<0.001). Admission hyperglycemia correlated moderate but significant to DE% (r=0.386, p<0.001) and NR% (r=0.421, p<0.001). In a multivariable logistic regression model admission hyperglycemia was an independent predictor (OR 6.8; CI 2.8 −16.6) of extensive (> median) microvascular obstruction, extensive delayed enhancement (OR 3.2; CI 1.5–7.1) and was associated with an increased risk for death and reinfarction (OR 4.7; CI 1.2–18.3) during follow up. Admission hyperglycemia in acute, reperfused STEMI is independently related to the extent of microvascular obstruction on early contrast-enhanced CMR and is associated with worse long-term outcome. Thus, CMR may play a major role in monitoring effects of glucose control on myocardial damage in AMI.

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