A Multivariate NIR Study of Skin Alterations in Diabetic Patients as Compared to Control Subjects

2000 ◽  
Vol 8 (4) ◽  
pp. 217-227 ◽  
Author(s):  
Paul Geladi ◽  
Josefina Nyström ◽  
Jan W. Eriksson ◽  
Anders Nilsson ◽  
Folke Lithner ◽  
...  

A group of 15 diabetic persons with different degrees of diabetes complications, including skin changes, was studied by Fourier Transform Near Infrared (FT-NIR) spectroscopy. Skin reflectance spectra were measured with a fibre-optic probe in four locations (sites): hand, arm, leg and foot. For reference, a group of 28 healthy controls was also measured. Multivariate analysis of the NIR spectra obtained shows a high potential for classification and discrimination of the skin conditions. Valuable indications for future experiments can be observed.

2002 ◽  
Vol 10 (3) ◽  
pp. 195-202 ◽  
Author(s):  
Tsuyoshi Furukawa ◽  
Yasuo Kita ◽  
Shigehiro Sasao ◽  
Kimihiro Matsukawa ◽  
Masahiro Watari ◽  
...  

The melt-extrusion transesterification of ethylene/vinylacetate (EVA) copolymer to ethylene/vinylalcohol (EVAL) copolymers has been monitored by on-line near infrared (NIR) spectroscopy. A total of 60 NIR spectra were measured within 37 minutes after the initial addition of octanol (reagent) and catalyst (sodium methoxide) at the exit of the extruder by use of a fibre-optic probe. The most significant intensity change is observed for a band at 7089 cm−1 due to the first overtone of an OH stretching mode of the EVAL copolymers. We can monitor the progress of the reaction by plotting the peak intensity at 7089 cm−1 only. A principal component analysis (PCA) was carried out for the series of NIR spectra in the 7300–6900 cm−1 region. A score plot of PCA factor 1 is almost identical with the plot of the peak intensity at 7089 cm−1. Calibration models for predicting the vinyl acetate content in EVA copolymers have been developed by use of partial least squares (PLS) regression. The correlation coefficient and standard error of prediction are 0.96 and 0.85%, respectively, indicating that the described technique can be used to monitor the transesterification reaction.


1993 ◽  
Vol 1 (2) ◽  
pp. 109-120 ◽  
Author(s):  
Jie Lin ◽  
Chris W. Brown

Near infrared (NIR) spectroscopy has been investigated as a new technique for the simultaneous determination of physical and chemical properties of NaCl solutions. The spectra of NaCl solutions (0 to 5 M) were measured with cuvettes in the 1100–2500 nm and 680–1230 nm regions at temperatures between 23.0 and 28.5°C, and with a fibre-optic probe in the 1100–1870 nm region at room temperature (23.0 ± 0.5°C). These spectra were correlated with various properties of NaCl solutions by principal component regression (PCR) and multilinear regression (MLR) models. The properties studied include water concentration, density, refractive index, relative viscosity, freezing point depression, osmolality, electrical conductance and activity coefficient of NaCl. Very good correlations were found between the NIR predicted values and literature values. The results of this study demonstrate that several properties of NaCl solutions can be determined simultaneously with NIR spectroscopy. Remote sensing of the properties can be performed with the use of a fibre-optic probe.


2002 ◽  
Vol 453 (2) ◽  
pp. 281-288 ◽  
Author(s):  
Inmaculada González-Martı́n ◽  
Claudio González-Pérez ◽  
Jesús Hernández-Méndez ◽  
Noelia Alvarez-Garcı́a ◽  
José-Luis Hernández Andaluz

2008 ◽  
Vol 16 (2) ◽  
pp. 111-119 ◽  
Author(s):  
Antonio J. Gaitán-Jurado ◽  
Francisco Rincón ◽  
Victor Ortiz-Somovilla ◽  
Fidelina España-España

1996 ◽  
Vol 50 (12) ◽  
pp. 1535-1540 ◽  
Author(s):  
Waldemar I. Friesen

The development of a reliable on-line method to monitor process streams is important for improved process control in oil sand extraction plants. The suitability of diffuse reflectance near-infrared (NIR) spectroscopy for this purpose has been tested in a pilot plant environment. Spectra of a feed slurry flowing through a pipe were measured with the use of an on-line fiber-optic probe. Data were collected throughout a nine-hour period during which ore type and slurry water content were varied. The feasibility of monitoring feed stream conditions is demonstrated by principal component analysis of the measured spectra. Clustering of these spectra according to ore type and water content enables the detection of deviations from and transitions between steady-state conditions of the process. Estimates are given of characteristic times for the process to reach a steady state after a change in condition has been initiated. The use of artificial neural networks for classifying spectra on the basis of ore type is also illustrated.


NIR news ◽  
2011 ◽  
Vol 22 (7) ◽  
pp. 11-13 ◽  
Author(s):  
Hoang Nam Nguyen ◽  
Frédéric Dehareng ◽  
Mohamed Hammida ◽  
Vincent Baeten ◽  
Eric Froidmont ◽  
...  

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