An Overview of Chemometrics Applications in near Infrared Spectrometry

1995 ◽  
Vol 3 (3) ◽  
pp. 119-132 ◽  
Author(s):  
Paul Geladi ◽  
Eigil Dåbakk
Keyword(s):  
Near Infrared ◽  
Multivariate Calibration ◽  
Infrared Spectrometry ◽  
Spectral Techniques ◽  
Forensic Research ◽  
Good Selection ◽  
Near Infrared Spectrometry ◽  
Selection Of

Near infrared (NIR) spectrometry has found wide use in academic applications, forensic research and in industry. While the use of NIR has been extended to new fields, there have also been enormous developments in the field of multivariate calibration. Some of these developments were due to demands in NIR applications while others came from related spectral techniques. In this paper some trends and developments in multivariate calibration and the use of NIR spectrometry are presented and commented upon. A complete overview would be quite impossible, but an attempt is made to present a good selection of what is going on in the field, with appropriate comments.

Determination of total protein in hyperimmune serum samples by near-infrared spectrometry and multivariate calibration

2010 ◽  
Vol 397 (2) ◽  
pp. 175-180 ◽  
Author(s):  
Ana Luiza Q. Baddini ◽  
Luiz Eduardo R. da Cunha ◽  
Antônia Maria C. de Oliveira ◽  
Ricardo J. Cassella
Keyword(s):  
Total Protein ◽  
Near Infrared ◽  
Multivariate Calibration ◽  
Infrared Spectrometry ◽  
Serum Samples ◽  
Hyperimmune Serum ◽  
Near Infrared Spectrometry

Efficacy of Near-Infrared Spectrometry for Monitoring the Cerebral Effects of Severe Dilutional Anemia

2014 ◽  
Vol 17 (3) ◽  
pp. 154 ◽  
Author(s):  
Arıtürk Cem ◽  
Ustalar Serpil ◽  
Toraman Fevzi ◽  
Ökten Murat ◽  
Güllü Ümit ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiac Surgery ◽  
Blood Lactate ◽  
Near Infrared ◽  
Bypass Graft ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Infrared Spectrometry ◽  
Control Group ◽  
Near Infrared Spectrometry

<p><strong>Introduction:</strong> Clear guidelines for red cell transfusion during cardiac surgery have not yet been established. The current focus on blood conservation during cardiac surgery has increased the urgency to determine the minimum safe hematocrit for these patients. The aim of this study was to determine whether monitoring of cerebral regional oxygen saturation (rSO<sub>2</sub>) via near-infrared spectrometry (NIRS) is effective for assessing the cerebral effects of severe dilutional anemia during elective coronary arterial bypass graft surgery (CABG).</p><p><strong>Methods:</strong> The prospective observational study involved patients who underwent cerebral rSO<sub>2</sub> monitoring by NIRS during elective isolated first-time CABG: an anemic group (<em>N</em>=15) (minimum Hemoglobin (Hb) N=15) (Hb &gt;8 g/dL during CPB). Mean arterial pressure (MAP), pump blood flow, blood lactate level, pCO<sub>2</sub>, pO<sub>2</sub> at five time points and cross-clamp time, extracorporeal circulation time were recorded for each patient. Group results statistically were compared.</p><p><strong>Results:</strong> The anemic group had significantly lower mean preoperative Hb than the control group (10.3 mg/dL versus 14.2 mg/dL; <em>P</em> = .001). The lowest Hb levels were observed in the hypothermic period of CPB in the anemic group. None of the controls exhibited a &gt;20% decrease in cerebral rSO<sub>2</sub>. Eleven (73.3%) of the anemic patients required an increase in pump blood flow to raise their cerebral rSO<sub>2</sub>.</p><p><strong>Conclusions:</strong> In this study, the changes in cerebral rSO<sub>2</sub> in the patients with low Hb were within acceptable limits, and this was in concordance with the blood lactate levels and blood-gas analysis. It can be suggested that NIRS monitoring of cerebral rSO<sub>2</sub> can assist in decision making related to blood transfusion and dilutional anemia during CPB.</p>

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