Lymph drainage in patients with joint immobility due to chronic ulcerated lesions

2008 ◽  
Vol 23 (1) ◽  
pp. 32-34 ◽  
Author(s):  
J M Pereira de Godoy ◽  
D M Braile ◽  
M de Fátima Guerreiro Godoy

The fibrous process of chronic ulcerated lesions of lower limbs can impair the mobility of the affected limb. The aim of this work was to assess the benefits of lymph drainage in patients who suffer from this disease. Twenty female and five male patients with ages ranging from 53 to 69 years (mean age 60.6 years) were evaluated. All had a history of at least 10 years of varicose veins and/or ulcerated lesions of the lower limbs with initial dermatofibrosis, with the positive Godet sign during the physical examination of the limb. Patients with intermittent claudication, diabetes and trauma were excluded from the study, as well as patients with chronic dermatofibrosis, and in whom positive Godet sign was not seen. Patients with immobility or very limited movement of the ankle and with some limitation in the toe joints were selected. The patients were randomly divided into group A comprising 15 individuals, and group B 10. All the individual treatments were established before the start of the evaluation period. Lymph drainage was performed on the patients of group A four or five times per week. Group B was subjected to a type of massage for the same period and at the same frequency. The mobility of the ankle joints was evaluated using goniometry before the start and after 30 days of treatment. In all the patients who underwent lymph drainage, an improvement of the joint mobility was seen, whereas in the control, group B, there was no obvious change. In conclusion, lymph drainage gave an improvement in the mobility of the ankle joint after impairment due to initial dermatofibrosis in patients with chronic ulcerated lesions.

2020 ◽  
Vol 4 (2) ◽  
pp. 69-71
Author(s):  
Bilqees Akhtar Malik ◽  
Ambreen Shabbir ◽  
Zeb-Un-Nisa ◽  
Asma Ambreen

Objective: In our part of the world poverty and illiteracy has adversely affected our core objective of pregnancy i.e. healthy mother and healthy child. Exploring the role of a routinely used drug in reducing the duration of labor could be a breakthrough. Present study was planned accordingly to evaluate the effect of phloroglucinol (PHL). Materials and Methods: It was a Randomized controlled trial conducted at Department of Obstetrics & Gynecology, Combined Military Hospital, Bahawalpur from January 2019 to June 2019. This study included 60 cases of age 18 to 40 years, having singleton pregnancy and in active first stage of uncomplicated labor. Patients with history of multiple pregnancies, obstetrical and surgical complications and cardiorespiratory diseases were excluded. The cases were placed randomly into Group A & Group B and given intravenous PHL and a placebo respectively. After this, duration of the first stage of labor was recorded in minutes from when there was 3-4 cm cervical dilatation with regular uterine contractions to complete cervical dilation i.e. 10 cm and descent of the presenting fetal part. Results: Mean duration of active first stage of labor in experimental group A (230.20 ± 52.96 minutes) was significantly higher than that of control group B (345.30 ± 50.57 minutes). Conclusion: This study concluded that intravenous PHL has efficiently reduced the duration of active first stage of labor in these randomly selected nulliparous and multiparous women. PHL is a useful drug serving the purpose of a spasmolytic, analgesic and labor augmentation at the same time.


2013 ◽  
Vol 21 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Md Manjurul Karim ◽  
Md Abdul Wahab ◽  
Lubna Khondoker ◽  
Md Shirajul Islam Khan

A case-control study conducted in the Department of Dermatology and Venereology of Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2008- December 2010. A total 60 female patients of telogen effluvium attending in outpatient department (OPD) were enrolled in the study with 30 having hair loss considered as case (Group-A) and another 30 females had no history of hair loss were considered as control (Group-B). The study included 60 patients and the mean age were 25.4±7 years ranging from 18 to 42 years in group A and 24.8±5.6 years ranging from 17 to 36 years in group B. Maximum number was found in the age group of 21- 30 years in both groups and nearly three fourth (73.4%) patients were unmarried in group A and 18(60.0%) in group B. Most of the patients were student in both groups, which were 21(70.0%) and 17(56.7%) in group A and group B respectively and majority of the the patients were HSC level in both groups, 15(50.0%) and 14(46.7%) in Group A and Group B respectively. Most of the patients came from middle class, which were 20(66.7%) and 16(53.3%) in group A and group B respectively. The mean serum ferritin were 18.8±8.1 g/L ranging from 4.5 to 36.54 g/L and 36.6±9.9 mg/L ranging from 18.46 to 56.3 mg/ L in group A and group B respectively. The mean Hb level was 11.5±1.4 gm/dl ranging from 8.5 to 14.0 gm/dl in group A and 12.8±1.1 gm/dl ranging from 10.5 to 14.5 gm/dl in group B. The mean difference of Hb level was statistically significant (p<0.05) between two groups in unpaired t-test. It can be concluded that low iron level is associated with telogen effluvium in women. DOI: http://dx.doi.org/10.3329/bjmed.v21i2.13617 Bangladesh J Medicine 2010; 21: 84-89


2005 ◽  
Vol 33 (4) ◽  
pp. 454-459 ◽  
Author(s):  
M Ozkan ◽  
O Baysan ◽  
K Erinc ◽  
C Koz ◽  
M Yokusoglu ◽  
...  

We aimed to evaluate the correlation between aortic regurgitation severity and brain natriuretic (BNP) levels as a marker for left ventricular dysfunction. Sixty consecutive male patients (mean age 22 ± 3 years) with isolated chronic aortic regurgitation were enrolled in the study together with a control group of 30 age-matched healthy volunteers (group A). Patients were classified with regard to aortic regurgitation vena contracta width as follows: group B, < 3 mm, mild ( n = 16); group C, ≥ 3 and < 6 mm, moderate ( n = 26); group D, ≥ 6 mm, severe ( n = 18). BNP measurements were performed with a fluorescence immunoassay kit. BNP levels were increased in patients with aortic regurgitation, and severity of regurgitation had a significant influence on BNP levels. This effect can be explained by the volume loading effect of aortic regurgitation.


2019 ◽  
pp. 253-258
Author(s):  
Ewelina Wawryk-Gawda ◽  
Michał K. Zarobkiewicz ◽  
Patrycja Chylińska-Wrzos ◽  
Barbara Jodłowska-Jędrych

Background. Smoking is frequently a way to control appetite and weight. The data concerning the body mass gain after quitting among the users of electronic cigarettes who have no prior history of smoking traditional cigarettes is inconsistent. Objective. In our study we have compared smoking and vaping impact on weight gain and glycaemia. Material and methods. 3 groups of rats were used. The group A was exposed to vapour and group B were exposed to smoke. Rats in the group C constituted the control group without nicotine exposition. Results. During 6 weeks of experiment weight gain of rats in the A and B groups was comparable, while animals from group C had gained signifi0cantly more. During 2 weeks after cessation of exposition to nicotine animals from group B gained more weight than rats of A and C group. Blood glucose was higher in group B than in groups A and C 24 h after last exposure to nicotine and 2 weeks after nicotine exposure cessation. Conclusion. Effects of vaping on weight increase is similar to smoking, but after vaping cassation weight gain is lower and comparable with nicotine nonusers.


2018 ◽  
Vol 5 (12) ◽  
pp. 3904
Author(s):  
Ahmed S. Elmallah ◽  
Yehia M. Alkhateeb ◽  
Said I. Elmallah

Background: There are different evolving minimally invasive surgical options for varicose veins (VV) treatment. This study compared Endo-venous Laser Ablation (EVLA) and foam sclerotherapy Vs high tie and multiple phlebectomy / ligation without vein stripping.Methods: 185 lower limbs with primary VV and sapheno-femoral junction (SFJ)incompetence were included. Patients were divided into two groups. Group A: 85 limbs in 78 patients (4 had chronic venous ulcers) were treated by EVLA & foam sclerotherapy under tumescent anesthesia. Group B: 100 limbs in 100 patients (5 had chronic venous ulcers) were treated by high tie and multiple phlebectomy/ ligation under local anesthesia. All patients had duplex ultrasound preoperative and 4 weeks and 1 year postoperatively. Postoperative outpatient follow-up was 4 weeks, 3, 6 and 12 months.Results: All procedures were successful. Early postoperative recurrence in 3 limbs (3.52%) in EVLA and no early recurrence in group B. Patients with venous ulcers healed within 3-5 weeks in both groups. Postoperative pigmentation was higher in group B. Mean time of procedure was 60-90 min and 60-150 min respectively. Significant pain in first week was more in group A (40 patients) than group B (22 patients) p<0.05. No DVT, wound infection, permanent nerve affection nor skin burn was recorded in both groups. Return to normal activities was quicker in Group B compared to group A but mean cost per limb was higher in Group B (1000 -1500 US $) versus Group A (500-750 US$).Conclusions: Both procedures are effective and safe in treating varicose veins. Minimally invasive surgery was less costly, more postoperative pain and was associated with longer operative time. EVLA was associated with more postoperative pigmentation and 1 year VV recurrence.


2020 ◽  
Vol 08 (11) ◽  
pp. 5021-5030
Author(s):  
Neethu Dev ◽  
Santosh Kumar J ◽  
SubhashRai N

Varicose vein of the lower limbs is one of such clinical condition that hampers the beauty of the legs. It is a very common condition, affecting up to three in 10 adults. Varicose veins affect up to 25% of women and 15% of men. By the age of 50, nearly 40% of women and 20% of men have significant vascular problems. The lifestyle changes, obesity, occupational pattern of prolonged standing and pregnancy are considered to be significantly contributing to this situation. Siravyadha, which is one among the types of Sasastra Rak-tamokashana is mentioned in the treatment of Sirajagranthi in our classics. It is considered as Ardha Chikitsa of Shalyatantra and is said to provide immediate results. Udvartana which is having Vatakapha-hara Twakprasadana and Siramukhavivechana property is said to be effective in Sirajagranthi. Also, the procedure is done in Pratiloma (upward) direction which results in Dridikarana of angas by toning them and relieves the symptoms of varicose vein. Hence an effort was made to evaluate the effect of Sira-vyadha by Vrihimukha Sastra and Udvartana with Kolakulathadi Churna in the management of Sira-jagranthi (varicose vein), this study was planned with the following aims. Objective: A detailed study on Sirajagranthi and its Management. To study the effect of Udvartana with Siravyadha in Sirajagranthi (varicose veins). To study the effect of Siravyadha in Sirajagranthi (varicose veins)., To compare the effi-cacy of both in Sirajagranthi (varicose veins). Method: The outcome of the study is evaluated clinically on a minimum of 60 patients with Sirajagranthi, divides 2 groups A and B. Group A received Udvartana for 7days and then Siravyadha on 8th day. Group B received Siravyadha for 1 day and followed by Pathya for 7days.The duration of study was 28days in both the groups and observations were made on be-fore and after the treatment (0th, 8th and 28th day). Data obtained was statistically analysed and interpreted. Results: The results were assessed based on the relief obtained to the subjective and objective parameters and was taken for consideration for the study and were found statistically significant on all the parameters (p<0.05). Conclusion: From the study it is evident that effectiveness of Udvartana along with Siravyadha is more significant in reducing the signs and symptoms of Sirajagranthi.


2021 ◽  
Vol 11 (6) ◽  
pp. 172-177
Author(s):  
Fernando BPA ◽  
Hettiarachchi GTK ◽  
Kumara GUA

Introduction: Hemorrhoids, also called piles, co-related with Arsha in Ayurveda, are swollen veins in the anus and the lower rectum, similar to varicose veins. Hemorrhoids can develop inside the rectum known as internal hemorrhoids or under the skin around the anus known as external hemorrhoids. Worldwide, the prevalence of symptomatic hemorrhoids is estimated at 4.4% in the general population. Objectives: This is a clinical study was conducted to evaluate the efficacy of the Sapta Winshati Guggulu in the management of Shushkarsha. Methodology: 40 patients diagnosed with Shushkarsha were randomly selected to this study and they were randomly divided into two groups and was named as the Group-A (Tested group) and the Group-B (Control group). All the patients (both A and B groups) were treated by Abhayarishta, Chirabilwa Kwatha and Sukumara Churna. Only Group-A (testing group) was additionally treated with Sapta Winshati Guggulu. Data collection: Subjective parameters such as pain and Objective parameters such as circumference of the pile and distance of the prolapse were collected. Data analysis: All the subjective and objective parameters were entered by using reputed methods and were analyzed by using graphs and figures and SPSS Statistical Software. Results: p-value and t-value of Group-A and Group-B were statistically significant. But, Significant level of Group-A was higher than Group-B. Conclusion: According to the findings, finally it can be concluded that the Sapta Winshati Guggulu has remarkable effect in the management of the Shushkarsha. Key words: Hemorrhoids, Piles, Shushkarsha, Chirabilwa Kwatha, Sapta Winshati Guggulu.


2020 ◽  
Vol 13 (11) ◽  
pp. 2330-2337
Author(s):  
Nasrin Sultana ◽  
Marzia Afrose ◽  
Kazi Rafiq

Aim: The study was conducted to observe the effects of dexamethasone (DEX) on the gross study and histomorphometry of liver and on the alterations of biochemical parameters of broilers. Materials and Methods: Ninety day-old chicks were collected and assigned to one of three groups: The control, Group A, and Group B. The control, Group A, and Group B were fed for 28 days with a homemade ration, a commercial broiler type ration, and a homemade ration with DEX (7 mg/kg feed), respectively. Liver samples were collected from the individual birds after sacrificing on days 7, 14, 21, and 28 of the experiment. Morphometric characteristics (length, weight, color, and texture) of the liver were examined. Histomorphological alterations of the liver were assessed with routine hematoxylin and eosin staining. To measure the biochemical parameters, blood samples were collected on days 7, 14, 21, and 28 of the experiment. Liver function test was performed spectrophotometrically by analyzing serum biochemical markers, that is, alanine aminotransferase (ALT), aspartate aminotransferase, and alkaline phosphatase (ALP). Thin-layer chromatography (TLC) was performed for the detection of hepatic steroids. Results: Hemorrhagic and congested livers were found in broilers of Group B. There were no significant changes found in weight and length of the livers; only numerical decrease in weight and length was observed in birds of Group B. Liver width was increased in Group B on day 21. Histological observation of livers showed accumulation of lipid droplets, congestion of the sinusoids, and central veins in broilers of Group B. Biochemical analyses showed increased levels of ALT in Group B as compared to Group A on day 14 of the experiment. TLC evaluation revealed a positive result in Group B on 28 days of the experiment. Conclusion: The present study results show that DEX may alter the liver morphology and the concentration of ALT in the circulation of broilers.


2020 ◽  
Author(s):  
Bing Xiao ◽  
Dou Fu ◽  
Wei Yang ◽  
Can Zou ◽  
Bing Zhang ◽  
...  

Abstract Purpose Previous studies have showed that age,sex and comorbidities might be associated with severity of patients infected with COVID-19 ,which endangers public health worldwide rapidly.The characteristics and length of negative conversion of Non-severe COVID-19 patients with or without hypertension is limited.This study aims to assess whether non-severe COVID-19 patients with hypertension undergone more longer period of negative conversion .Methods This single-center, retrospective study was performed in Xiantao first People’s Hospital Affiliated to Yangtze University(xiantao, hubei,China) by using medical records.Non-severe COVID-19 patients with a history of hypertension From January 23 to February15 were enrolled as group A. A Control group(group B) was matched (1:1) according to age,sex and the admission date.Data on clinical records, laboratory results, and radiological tests was collected. we conducted all analyses with SPSS software(22.0).Results We enrolled 24 and 24 Non-severe COVID-19 patients with and without hypertension, respectively. The most common symptoms were fever and cough in both groups.The frequency of fatigue is more in patients with hypertension.The levels of AST,ALT and CRP were higher in group A.The mean periods of negative conversion for COVID-19 virus were 17 days(SD:5.5) and 15 days(SD:3.6)for patients with and without hypertension(P=0.021).The mean hospitalization periods were 16.8 days (SD:5.6) and 13.7 days (SD:3.8) , respectively (p=0.083) .Conclusion Non-severe COVID-19 patients with hypertension undergone a longer negative conversion for COVID-19 virus and spent more time on clearing COVID-19 virus.


1970 ◽  
Vol 6 (1) ◽  
pp. 23-26 ◽  
Author(s):  
MR Islam ◽  
MSR Khan ◽  
MA Islam ◽  
MEH Kayesh ◽  
MR Karim ◽  
...  

A total of 80 experimentally reared backyard chicks with the history of non-vaccinated parents to FPV vaccine were used for the determination of persistence of maternally derived antibody in chicks and to compare the efficacy of Poxine® and DLS-FPV vaccine in protecting the chicks. Chicks were divided into five groups namely group A, B, C, D and E where each group contained 15 chicks except group A contained 20 chicks which was also used to determine the persistence of maternally derived antibody (MDA). Birds of group B and C were vaccinated with DLS-FPV at day 22 and 18 respectively through wing web puncture (WWP), whereas group D and E were vaccinated with Poxine® at day 36 and 18 respectively. Sera were randomly colleted from 10 chicks of each group at 7, 14 and 21 days of post vaccination for the determination of antibody titre using PHA test. Ten chickens from each group were challenged three weeks post vaccination with 106 EID50/0.1ml. "Take reaction" was recorded to assess the better immune response in different groups after vaccination. Birds of group B, C, D and E showed 100, 86.67, 93 and 86.67% "take reaction", respectively. The highest Mean PHA titre was found 217.60 ± 19.55 in the chicks of group B. After challenge, the birds of group B and D showed 100% protection, whereas birds of group C and E showed 93.33% protection and control group showed no protection. From the results of PHA test it may be concluded that both Poxine® and DLS-FPV vaccines are equally suitable and the chicks of nonvaccinated origin might be vaccinated with DLS-FPV at day 18 or 22 and 36 in case of Poxine® fowl pox virus vaccine. Key words: Efficacy, fowl pox virus vaccine, backyard chicks, age DOI = 10.3329/bjvm.v6i1.1334 Bangl. J. Vet. Med. (2008). 6 (1): 23-26


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