Fever of unknown origin in the elderly: nine years experience in China

2008 ◽  
Vol 38 (4) ◽  
pp. 221-222 ◽  
Author(s):  
Minghua Zheng ◽  
Hailong Lin ◽  
Sheng Luo ◽  
Lihua Xu ◽  
Yanjun Zeng ◽  
...  

This is a retrospective study of older patients admitted to the First and Second Affiliated Hospitals of Wenzhou Medical College, China, with a diagnosis of fever of unknown origin. The study took place from January 1998 to December 2006 among 102 patients who fulfilled the criteria. Infections were responsible for 50 cases (49.1%), followed by no diagnosis in 27 (26.5%), miscellaneous in nine (8.8%), neoplasms in eight (7.8%) and connective tissue disease in another eight (7.8%). Mycobacterium TB was the most frequent type of infection diagnosed.

1989 ◽  
Vol 16 (2) ◽  
pp. 501-513
Author(s):  
Kenneth M. Wakefield ◽  
Scott T. Henderson ◽  
Jerry G. Streit

1990 ◽  
Vol 64 (3) ◽  
pp. 335-341 ◽  
Author(s):  
Hiroshi FUKUHARA ◽  
Kazunori TAMAKI ◽  
Hiroaki NAKAMURA ◽  
Hiroshi KANESIMA ◽  
Yuei IRABU ◽  
...  

2010 ◽  
Vol 37 (4) ◽  
pp. 783-786 ◽  
Author(s):  
BATSI CHIKURA ◽  
TONIA MOORE ◽  
JOANNE MANNING ◽  
ANDY VAIL ◽  
ARIANE L. HERRICK

Objective.To conduct a retrospective study to assess whether the degree of thumb involvement differs between primary Raynaud’s phenomenon (PRP) and secondary Raynaud’s phenomenon (SRP).Methods.Thermography images from all patients attending Salford Royal Hospital and referred for thermography for assessment of RP between 2004 and 2006 were retrospectively reviewed. A distal dorsal difference (DDD) of −1°C or less between the fingertips and dorsum of the hand (fingers cooler) at 23°C was considered clinically relevant. The worse score (the lower score, i.e., the more negative value) from each pair of digits was considered for analysis.Results.One hundred seventy patients fulfilled the study criteria. DDD at 23°C for the thumbs were significantly higher (digital tips warmer) compared with other digits (p < 0.001) in both PRP and SRP. All digits were significantly warmer in PRP compared to SRP with the exception of the thumbs. The proportion of patients with clinically relevant involvement of thumbs was significantly higher in SRP compared to PRP (p = 0.003) and this difference was more pronounced in the thumbs compared with other digits.Conclusion.Although the median temperature gradient along the thumb was not significantly different between SRP and PRP, the thumb is more likely to be involved in SRP than in PRP. Thumb involvement is one of a number of clinical indicators that should alert the clinician to the possibility of an underlying connective tissue disease/disorder.


1992 ◽  
Vol 92 (5) ◽  
pp. 197-210 ◽  
Author(s):  
Barbara Berland ◽  
Richard A. Gleckman

BMJ Open ◽  
2013 ◽  
Vol 3 (12) ◽  
pp. e003971 ◽  
Author(s):  
Toshio Naito ◽  
Masafumi Mizooka ◽  
Fujiko Mitsumoto ◽  
Kenji Kanazawa ◽  
Keito Torikai ◽  
...  

2014 ◽  
Vol 99 (1) ◽  
pp. 2-7 ◽  
Author(s):  
Ali İnal ◽  
Tulay Akman ◽  
Sebnem Yaman ◽  
Selcuk Cemil Ozturk ◽  
Caglayan Geredeli ◽  
...  

Abstract There is very little information about breast cancer characteristics, treatment choices, and survival among elderly patients. The purpose of this multicenter retrospective study was to examine the clinical, pathologic, and biologic characteristics of 620 breast cancer patients age 70 years or older. Between June 1991 and May 2012, 620 patients with breast cancer, recruited from 16 institutions, were enrolled in the retrospective study. Patients had smaller tumors at diagnosis; only 15% of patients had tumors larger than 5 cm. The number of patients who had no axillary lymph node involvement was 203 (32.7%). Ninety-three patients (15.0%) had metastatic disease at diagnosis. Patients were characterized by a higher fraction of pure lobular carcinomas (75.3%). The tumors of the elderly patients were also more frequently estrogen receptor (ER) positive (75.2%) and progesterone receptor (PR) positive (67.3%). The local and systemic therapies for breast cancer differed according to age. An association between age and overall survival has not been demonstrated in elderly patients with breast cancer. In conclusion, the biologic behavior of older patients with breast cancer differs from younger patients, and older patients receive different treatments.


2021 ◽  
Vol 28 (04) ◽  
pp. 552-556
Author(s):  
Aysha Mansoor Lodhi ◽  
Wajiha Rizwan ◽  
Mubeen Nazar ◽  
Asma Mushtaq ◽  
Muhammad Sahir Saud ◽  
...  

Objectives: To determine the etiology of Fever of Unknown Origin (FUO) in children. Study Design: Prospective Observational study. Setting: Department of Pediatric Medicine, The Children's Hospital, Lahore. Period: August 2019 to January 2020. Material & Methods: A total of 45 children aged between 01 to 180 months (15 years), having FUO were included. FUO was defined as a temperature of greater than 100.4ºF documented by a health care provider, persisting over a period of three weeks and for which no cause could be identified after at least 8 days of evaluation. All the study information was analyzed by using standard software SPSS 20. The quantitative variables like age and duration of fever before hospital admission were presented as mean and standard deviation. Qualitative variables like sex, antibiotic therapy use before definitive diagnosis and various diagnoses made were presented as frequencies and percentages. Results: The patient’s age range was from 01 to 180 months with mean of 80±45.12 months and male to female ratio was 2.2:1. Definitive diagnosis was made in 37(82.2%) patients. Infections were the predominant cause of FUO (44.4%) followed by malignancy (24.4%). Tuberculosis was the most common infection while Acute Lymphoblastic leukemia dominated the malignancy. Systemic lupus erythematosus was the most commonly diagnosed connective tissue disorder.  There was a significant association between duration of fever and the ultimate diagnosis (p=0.01). Conclusion: Infectious diseases were the most common cause of FUO followed by malignancy, connective tissue disorders and miscellaneous causes.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Anoshirwan Andrej Tavakoli ◽  
Miriam Reichert ◽  
Tanja Blank ◽  
Dietmar Dinter ◽  
Sabine Weckbach ◽  
...  

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