High resolutionT1 weighted magnetic resonance imaging of the deep brain structures using a reduced bandwidth

1995 ◽  
Vol 68 (807) ◽  
pp. 261-265 ◽  
Author(s):  
R Sigal ◽  
J Bittoun ◽  
O Jolivet ◽  
N Behnam ◽  
M Suminski ◽  
...  
2021 ◽  
Vol 11 (10) ◽  
pp. 969
Author(s):  
Patrick J. McCarty ◽  
Andrew R. Pines ◽  
Bethany L. Sussman ◽  
Sarah N. Wyckoff ◽  
Amanda Jensen ◽  
...  

Resting-state functional magnetic resonance imaging provides dynamic insight into the functional organization of the brains’ intrinsic activity at rest. The emergence of resting-state functional magnetic resonance imaging in both the clinical and research settings may be attributed to recent advancements in statistical techniques, non-invasiveness and enhanced spatiotemporal resolution compared to other neuroimaging modalities, and the capability to identify and characterize deep brain structures and networks. In this report we describe a 16-year-old female patient with autism spectrum disorder who underwent resting-state functional magnetic resonance imaging due to late regression. Imaging revealed deactivated networks in deep brain structures involved in monoamine synthesis. Monoamine neurotransmitter deficits were confirmed by cerebrospinal fluid analysis. This case suggests that resting-state functional magnetic resonance imaging may have clinical utility as a non-invasive biomarker of central nervous system neurochemical alterations by measuring the function of neurotransmitter-driven networks. Use of this technology can accelerate and increase the accuracy of selecting appropriate therapeutic agents for patients with neurological and neurodevelopmental disorders.


2015 ◽  
Vol 11 (3) ◽  
pp. 412-419 ◽  
Author(s):  
Jonathan A Hyam ◽  
Harith Akram ◽  
Thomas Foltynie ◽  
Patricia Limousin ◽  
Marwan Hariz ◽  
...  

Abstract BACKGROUND Magnetic resonance imaging (MRI)-verified deep brain stimulation relies on the correct interpretation of stereotactic imaging documenting lead location in relation to visible anatomic target. However, it has been suggested that local signal distortion from the lead itself renders its depiction on MRI unreliable. OBJECTIVE To compare lead location on stereotactic MRI with subsequent location of its brain track after removal. METHODS Patients underwent deep brain stimulation with the use of MRI-guided and MRI-verified Leksell frame approach. Infection or suboptimal efficacy required lead removal and subsequent reimplantation by using the same technique. Postimplantation stereotactic MR images were analyzed. Lateral (x) and anteroposterior (y) distances from midcommissural point to center of the lead hypointensity were recorded at the anterior commissure-posterior commissure plane (pallidal electrode) or z = −4 (subthalamic electrode). Stereotactic MRI before the second procedure, x and y distances from the center of the visible lead track hypointensity to midcommissural point were independently recorded. Vectorial distance from center of the lead hypointensity to the center of its track was calculated. RESULTS Sixteen electrode tracks were studied in 10 patients. Mean differences between lead artifact location and lead track location were: x coordinate 0.4 mm ± 0.2; y coordinate 0.6 mm ± 0.3. Mean vectorial distance was 0.7 mm ± 0.2. CONCLUSION Stereotactic distance between lead location and subsequent brain track location on MRI was small. The mean discrepancy was approximately half the deep brain stimulation lead width. This suggests that lead hypointensity seen on postimplantation MRI is indeed an accurate representation of its real location within deep brain structures.


2019 ◽  
Vol 84 ◽  
pp. 142-146 ◽  
Author(s):  
Ahmed Razek ◽  
El-hadidy Mohamed El-Hadidy ◽  
Mohamed El-Said Moawad ◽  
Nader El-Metwaly ◽  
Amr Abd El-hamid El-Said

2021 ◽  
Vol 9 (7) ◽  
pp. 1781-1786
Author(s):  
Ze’ai Wang ◽  
Yanfeng Wang ◽  
Yuan Wang ◽  
Chaogang Wei ◽  
Yibin Deng ◽  
...  

Biomineralized iron oxide–polydopamine hybrid nanodots are constructed using albumin nanoreactors to facilitate contrast-enhanced T1-weighted magnetic resonance imaging as well as photothermal therapeutic efficacy.


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