scholarly journals Risk Factors of Nosocomial Infection for Infants in Neonatal Intensive Care Units: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 25 ◽  
pp. 8213-8220
Author(s):  
Li Wang ◽  
Ke-Ning Du ◽  
Yan-Ling Zhao ◽  
Ya-Juan Yu ◽  
Li Sun ◽  
...  
2018 ◽  
Vol 5 (3) ◽  
pp. 207-215
Author(s):  
Ting-Ting Liu ◽  
Meng-Jie Lei ◽  
Yu-Feng Li ◽  
Ya-Qian Liu ◽  
Li-Na Meng ◽  
...  

Abstract Objective This meta-analysis aimed to examine the effects of parental involvement in infant care in neonatal intensive care units (NICUs). Methods PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang database, and VIP database were searched till November 2017. Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) examining the effect of parental involvement in the NICU were considered for inclusion. Results We included 10 studies (three RCTs, seven CCTs) with a total of 1,851 participants. The meta-analysis demonstrated that there were no statistically significant differences on nosocomial infection between two groups (risk ratio [RR] = 0.90, 95% CI 0.63–1.30, P = 0.58). Compared with no parental involvement groups, parental involvement groups showed more weight gain (mean difference [MD] = 1.47, 95% CI 0.65–2.29, P < 0.05), higher breast-feeding rate (RR = 1.38, 95% C11.25–1.53, P < 0.05), lower readmission rate (RR = 0.35, 95% CI 0.15–0.80, P < 0.05), and higher satisfaction rate (RR = 1.09, 95% CI 1.02–1.16, P< 0.05). Conclusions Parental involvement in the NICU interventions could not increase the rate of nosocomial infection of neonates, but could improve their weight gain, breast-feeding and parental satisfaction and decrease their readmission. However, since the conclusion of this meta-analysis was drawn based on the limited number of high-quality RCTs, more high-quality studies should be conducted in the future to confirm its positive intervention effects.


2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Yunxia Leng ◽  
Wenzhi Huang ◽  
Guoliang Ren ◽  
Cheng Cai ◽  
Qingbiao Tan ◽  
...  

Author(s):  
S Bello ◽  
EA Bamgboye ◽  
DT Ajayi ◽  
EN Ossai ◽  
EC Aniwada ◽  
...  

Background: Compliance with handwashing in busy healthcare facilities, such as intensive care units (ICUs), is suboptimal and alcohol hand-rub preparations have been suggested to improve compliance. There is no evidence on the comparative effectiveness between handwash and hand-rub strategies. This systematic review was to assess the effectiveness of handwash versus hand-rub strategies for preventing nosocomial infection in ICUs. Methods Studies conducted in ICUs and indexed in PubMed comparing the clinical effectiveness and adverse events between handwash and hand-rub groups were included in a systematic review. The primary outcome was nosocomial infection rates. Secondary outcomes included microbial counts on healthcare providers’ hands, mortality rates, patient/hospital cost of treatment of healthcare-associated infections (HCAIs), length of ICU/hospital stays, and adverse events. Studies were independently screened and data extracted by at least two authors. Meta-analyses of risk ratios (RR), incidence rate ratios (IRR), odds ratios (OR) and mean differences (MD), were conducted using the RevMan 5.3 software. Results: Seven studies published between 1992-2009 and involving a total of 11,663 patients were included. Five studies (10,981 patients) contributed data to the ICU acquired nosocomial infection rates. The pooled IRR was 0.71 (95% CI 0.61, 0.82; I2 = 94%). On sensitivity analysis, pooled IRR was 0.39 (95% CI 0.32, 0.48; 4 studies; 8,247 patients; I2 = 0%) in favour of hand rub. The pooled OR for mortality was 0.95 (95% CI 0.78, 1.61; 4 studies; 3,475 patients; I2 = 39%). The pooled MD for length of hospital stay was -0.74 (95% CI -2.83, 1.34; 3 studies; 741 patients; I2 = 0%). The pooled OR for an undesirable skin effect was 0.37 (95% CI 0.23, 0.60; 3 studies;1504 patients; I2 = 0%) in favour of hand rub. Overall quality of evidence was low. Conclusion: Hand rub appeared more effective when compared to handwash in ICUs.


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