scholarly journals Method for Detecting the Expression of Bone Matrix Protein by in situ Hybridization Using Decalcified Mineralized Tissue.

1993 ◽  
Vol 26 (4) ◽  
pp. 303-309 ◽  
Author(s):  
SHINTARO NOMURA ◽  
KIMIAKI HIRAKAWA ◽  
JUNSUKE NAGOSHI ◽  
SEIICHI HIROTA ◽  
HYUNG-MIN KIM ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Matrix Protein ◽  
Bone Matrix ◽  
Mineralized Tissue ◽  
Bone Matrix Protein

scholarly journals DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis

2006 ◽  
Vol 38 (11) ◽  
pp. 1248-1250 ◽  
Author(s):  
Bettina Lorenz-Depiereux ◽  
Murat Bastepe ◽  
Anna Benet-Pagès ◽  
Mustapha Amyere ◽  
Janine Wagenstaller ◽  
...  
Keyword(s):  
Autosomal Recessive ◽  
Matrix Protein ◽  
Bone Matrix ◽  
Phosphate Homeostasis ◽  
Bone Matrix Protein

Induction of Bone Matrix Protein Expression by Native Bone Matrix Proteins in C2C12 Culture

2009 ◽  
Vol 22 (2) ◽  
pp. 164-169 ◽  
Author(s):  
Zhen-Ming HU ◽  
Sean A.F. PEEL ◽  
Stephen K.C. HO ◽  
George K.B. SANDOR ◽  
Cameron M.L. CLOKIE
Keyword(s):  
Protein Expression ◽  
Matrix Protein ◽  
Bone Matrix ◽  
Matrix Proteins ◽  
Native Bone ◽  
Bone Matrix Proteins ◽  
Bone Matrix Protein

Analysis of Osteoblast Activity around Beta-TCP Particles Implanted into Bone: Expression of Bone Matrix Protein mRNAs

2000 ◽  
Vol 192-195 ◽  
pp. 317-320
Author(s):  
Kunitaka Ohsawa ◽  
Masashi Neo ◽  
Hiroyuki Matsuoka ◽  
H. Akiyama ◽  
H. Ito ◽  
...  
Keyword(s):  
Matrix Protein ◽  
Bone Matrix ◽  
Osteoblast Activity ◽  
Bone Matrix Protein

scholarly journals Fibronectin mRNA in the developing glomerular crescent in rabbit antiglomerular basement membrane disease.

1995 ◽  
Vol 5 (12) ◽  
pp. 2087-2090
Author(s):  
S P Sady ◽  
M Goyal ◽  
P E Thomas ◽  
B L Wharram ◽  
R C Wiggins
Keyword(s):  
Wound Healing ◽  
In Situ Hybridization ◽  
Basement Membrane ◽  
Matrix Protein ◽  
Crescent Formation ◽  
Plasma Phase ◽  
Two Phases ◽  
Fibronectin Mrna ◽  
In Cells

Fibronectin is a multifunctional matrix protein important in wound healing that is markedly increased in glomerular crescents. A previous report established two phases of fibronectin metabolism in crescent formation in an anti-glomerular basement membrane model of crescentic nephritis in the rabbit. Phase I was associated with increased glomerular fibronectin content from plasma. Phase II was associated with increased fibronectin mRNA in glomeruli. To examine the hypothesis that fibronectin is synthesized in the developing crescent, rabbit fibronectin cDNA was cloned, sense and antisense riboprobes were prepared and their specificity under the conditions to be used was validated and in situ hybridization studies were performed in the model. The results showed that the cells in the developing glomerular crescent express an intense fibronectin mRNA signal at Day 7 and that this signal persisted in cells of the crescent at Day 14. This result shows that fibronectin synthesis does indeed take place in cells of the developing crescent in this model and supports the hypothesis that fibronectin may be an important agent regulating crescent formation and fibrosis.

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