scholarly journals Equine Laminitis: A retrospective study of 55 cases (2000-2004)

2017 ◽  
Vol 58 (2) ◽  
pp. 107 ◽  
Author(s):  
I. PAPAKONSTANTIS (Ι. ΠΑΠΑΚΩΝΣΤΑΝΤΗΣ) ◽  
N. DIAKAKIS (Ν. ΔΙΑΚΑΚΗΣ) ◽  
M. PATSIKAS (Μ. ΠΑΤΣΙΚΑΣ) ◽  
A. DESIRIS (Α. ΔΕΣΙΡΗΣ)
Keyword(s):  
Veterinary Medicine ◽  
Retrospective Study ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Good Prognosis ◽  
Diagnostic Approach ◽  
Inflammatory Drug ◽  
Therapeutic Protocol ◽  
Key Points ◽  
Therapeutic Protocols

Laminitis is a common equine disease. In order to have a good prognosis, prompt therapy is essential. Fifty-five cases of equine laminitis, that were treated in the Clinic of Surgery, School of Veterinary Medicine, were included in this study. More specifically, the clinical presentation and the diagnostic approach are described and the therapeutic protocol is evaluated. At the same time, the literature is reviewed as far as the epidemiology, the pathogenesis, the clinical signs, the diagnosis and the treatment is concerned. It is worth mentioning that several therapeutic protocols have been put forward for the treatment of laminitis, perhaps due to the fact that its pathogenesis is still under dispute. Prolonged rest, frog support, cols hosing of the feet, severe diet, administration of antibiotics and non-steroidal anti-inflammatory drug were the key points of the protocol of this study that led to extremely good results for the majority of the cases.

Feline Histoplasmosis: A Retrospective Study of 22 Cases (1986–2009)

2012 ◽  
Vol 48 (3) ◽  
pp. 182-187 ◽  
Author(s):  
Harmeet K. Aulakh ◽  
Karanvir S. Aulakh ◽  
Gregory C. Troy
Keyword(s):  
Overall Survival ◽  
Weight Loss ◽  
Veterinary Medicine ◽  
Pulmonary Disease ◽  
Clinical Evidence ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Disease Diagnosis ◽  
Regional College ◽  
Common Laboratory

Twenty-two cases of feline histoplasmosis seen at the Virginia-Maryland Regional College of Veterinary Medicine Teaching Hospital between 1986 and 2009 were reviewed. The median age of affected cats was 9 yr (mean, 8.8 yr). Female domestic shorthairs were more commonly affected. The clinical presentation of most cases was nonspecific. The most common presenting complaints included weakness, lymphadenopathy, weight loss, and anorexia. Less frequent clinical signs included vomiting, diarrhea, blindness, and lameness. Less than half of the cats had clinical evidence of pulmonary disease on admission. Anemia and hypoalbuminemia were common laboratory abnormalities. An interstitial pattern was the most common radiographic pattern observed with pulmonary disease. Diagnosis was based on identification of the organism on cytology or histopathology. Fifteen of the 22 cats were treated, and itraconazole was the most common antifungal agent prescribed. Median duration of the antifungal treatment was 5 mo for cats that survived to discharge. Overall survival at time of discharge for cats in this study was 55%.

Feline maculopapular cutaneous mastocytosis: a retrospective study of 13 cases and proposal for a new classification

2018 ◽  
Vol 21 (4) ◽  
pp. 394-404 ◽  
Author(s):  
Jerome Ngo ◽  
Marie-Anne Morren ◽  
Christine Bodemer ◽  
Marianne Heimann ◽  
Jacques Fontaine
Keyword(s):  
Retrospective Study ◽  
Spontaneous Regression ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Case Series ◽  
Human Condition ◽  
Urticaria Pigmentosa ◽  
New Classification ◽  
Human Form ◽  
Cutaneous Mastocytosis

Case series summary Cutaneous mastocytosis is a disorder rarely reported in veterinary dermatology and usually described as ‘urticaria pigmentosa’. This study aimed to evaluate the diagnosis, treatment and outcome of 13 affected cats, selected from the files of a private referral dermatology practice within a period of 14 years. Breeds of the affected individuals included Sphynx (n = 9), Devon Rex (n = 2) and Sphynx/Devon Rex crossbreeds (n = 2). Females (n = 9) were over-represented and the median duration of clinical signs prior to diagnosis was 8 months. The clinical presentation of these 13 cats was compared with cases reported in the veterinary literature and classified according to the current human consensus on cutaneous mastocytosis. Three clinical forms could be distinguished in cats: (1) large papular lesions and wheals, typically localised to the head, shoulders, ventral neck and axillae, and which may spontaneously resolve (termed polymorphic maculopapular cutaneous mastocytosis); (2) erythematous dermatitis, characterised by small maculopapular lesions often associated with crusts and with a poorer prognosis (termed monomorphic maculopapular cutaneous mastocytosis); and (3) more chronic dermatitis characterised by lichenification and hyperpigmentation, similar to the human condition ‘urticaria pigmentosa’ (termed pigmented maculopapular cutaneous mastocytosis). Histopathology was performed in eight cases and revealed a superficial-to-deep dermatitis characterised by infiltrates of mast cells and eosinophils. The response to various treatments, including antihistamines, steroids and ciclosporin, was variable. Relevance and novel information This article reports 13 new cases of feline cutaneous mastocytosis, confirming the clinical presentation and apparent breed predisposition. The feline maculopapular cutaneous mastocytosis seems to be clinically very close to the human form. This study proposes a new classification system for the feline disease based on the current human consensus, clinical presentation and prognosis, with three different subforms: polymorphic maculopapular cutaneous mastocytosis with eventual spontaneous regression; monomorphic maculopapular cutaneous mastocytosis with chronic evolution; and pigmented maculopapular cutaneous mastocytosis.

Feline sialocoele: clinical presentation, treatment and outcome in 19 cases

2021 ◽  
pp. 1098612X2110461
Author(s):  
Diego Bobis-Villagrá ◽  
Matteo Rossanese ◽  
Daniela Murgia ◽  
Guido Pisani ◽  
Rosario Vallefuoco ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Signs ◽  
Good Prognosis ◽  
Case Selection ◽  
Parotid Duct ◽  
Duct Ligation ◽  
Referral Hospitals ◽  
Stab Incision ◽  
Clinical Records

Objectives The aim of this retrospective observational study was to describe the clinical presentation, treatment and outcome of cats with sialocoele. Methods Clinical records from seven referral hospitals were retrospectively searched to identify cats with sialocoele between 2007 and 2021. Results Nineteen cats were identified. The most common clinical signs were ptyalism, dysphagia and anorexia. Localisation of the sialocoele was cervical (n = 6), sublingual (n = 6), cervical/sublingual (n = 3), facial (n = 2), cervical/pharyngeal (n = 1) and zygomatic (n = 1). The affected salivary glands were mandibular–sublingual (n = 15), mandibular–sublingual/parotid (n = 1), zygomatic/parotid (n = 1) and parotid (n = 2). The aetiology of the sialocoele was traumatic in two cases, neoplastic in one cat and unknown in 16 cats. Sialoadenectomy was performed in 11 cats. Other treatments included ranula marsupialisation (n = 3), needle drainage (n = 2), single stab incision (n = 2) and parotid duct ligation (n = 1). The median follow-up time was 399 days (range 15–1460). Postoperative seroma was the only complication observed in one cat. No recurrence was reported. Conclusions and relevance Feline salivary sialocoele are relatively rare and have a good prognosis. They can be managed successfully with sialoadenectomy; however, a more conservative approach can be used with appropriate case selection.

Ultrasound-guided removal of vegetal foreign bodies in the lower extremities of dogs: a retrospective study of 19 cases

2017 ◽  
Vol 86 (5) ◽  
pp. 285-290
Author(s):  
E. Fauchon ◽  
C. Lassaigne ◽  
G. Ragetly ◽  
E. Gomes
Keyword(s):  
Retrospective Study ◽  
Foreign Bodies ◽  
Clinical Signs ◽  
Lower Extremities ◽  
Invasive Procedure ◽  
Good Prognosis ◽  
Ultrasound Guided ◽  
First Choice ◽  
Short And Long Term ◽  
And Migration

Subcutaneous abscesses or granulomas in the lower extremities of dogs commonly occur secondary to the penetration and migration of vegetal foreign bodies (FBs). The aim of this study was to describe the clinical presentation and ultrasonographic appearance of intact grass awn FBs in the lower extremities of dogs, and their ultrasound-guided retrieval with particular emphasis on the feasibility, effectiveness and prognosis associated with this technique. In this retrospective study, 22 FBs were identified ultrasonographically in 19 dogs. The procedure resulted in the successful retrieval of the FB in 100% of dogs, and the clinical signs resolved in 90% (n=17) in less than ten days. No complications or recurrence were encountered. This study shows that ultrasonographic examination should be the first-choice modality when a vegetal FB is suspected within the distal extremity, as it allows both identification and removal of the FB with a minimally invasive procedure, with short- and long-term effectiveness and good prognosis.

scholarly journals Diagnostic Approach to Health Care- and Device-Associated Central Nervous System Infections

2018 ◽  
Vol 56 (11) ◽  
Author(s):  
Ryan M. Martin ◽  
Lara L. Zimmermann ◽  
Mindy Huynh ◽  
Christopher R. Polage
Keyword(s):  
Health Care ◽  
Central Nervous System ◽  
Nervous System ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Diagnostic Approach ◽  
Central Nervous System Infections ◽  
Cns Infections ◽  
Neurosurgical Patients ◽  
Definition Of

ABSTRACTHealth care- and device-associated central nervous system (CNS) infections have a distinct epidemiology, pathophysiology, and microbiology that require a unique diagnostic approach. Most clinical signs, symptoms, and tests used to diagnose community-acquired CNS infections are insensitive and nonspecific in neurosurgical patients due to postsurgical changes, invasive devices, prior antimicrobial exposure, and underlying CNS disease. The lack of a standardized definition of infection or diagnostic pathway has added to this challenge. In this review, we summarize the epidemiology, microbiology, and clinical presentation of these infections, discuss the issues with existing microbiologic tests, and give an overview of the current diagnostic approach.

Surgical management of choke through oesophagotomy in a buffalo: A case report

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
Devasee Borakhatariya ◽  
A. B. Gadara
Keyword(s):  
Case Report ◽  
Surgical Management ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Thoracic Inlet ◽  
Cervical Oesophagus ◽  
Foreign Objects ◽  
History Of ◽  
Oesophageal Obstruction ◽  
Large Animals

Oesophageal disorders are relatively uncommon in large animals. Oesophageal obstruction is the most frequently encountered clinical presentation in bovine and it may be intraluminal or extra luminal (Haven, 1990). Intraluminal obstruction or “choke” is the most common abnormality that usually occurs when foreign objects, large feedstuff, medicated boluses, trichobezoars, or oesophageal granuloma lodge in the lumen of the oesophagus. Oesophageal obstructions in bovine commonly occur at the pharynx, the cranial aspect of the cervical oesophagus, the thoracic inlet, or the base of the heart (Choudhary et al., 2010). Diagnosis of such problem depends on the history of eating particular foodstuff and clinical signs as bloat, tenesmus, retching, and salivation

scholarly journals Appendiceal Neuroendocrine Tumours - Experience of One Service

2021 ◽  
Author(s):  
Vítor Devezas ◽  
Laura Elisabete Barbosa
Keyword(s):  
Retrospective Study ◽  
Acute Appendicitis ◽  
Neuroendocrine Tumours ◽  
Adult Population ◽  
Right Hemicolectomy ◽  
Good Prognosis ◽  
Alive Today

AbstractTumours of the appendix are rare and tend to be diagnosed incidentally, in cases of acute appendicitis. For some authors, appendiceal neuroendocrine tumours (ANETs) are the most frequent neoplasm of the appendix, observed in 0.3% to 0.9% of cases acute appendicitis. The present is a unicentric retrospective study conducted between January 2005 and March 2017. Out of a total of 3,007 surgeries for appendiceal pathologies performed in the adult population at the hospital where the present study was conducted, there were 70 (2.33%) malignant cases, 20 (28.6%) of which were ANETs. The patients had a median age of 44 years (range: 18 to 85 years), and were predominantly women (there were 1.9 times more women than men). In 16 cases (80%), a simple appendicectomy was performed (1 patient was submitted to a right hemicolectomy later). The cases of ANETs had a good prognosis in our series: 85% of the patients are either alive today or were alive after 5 years of follow-up. Despite the fact that ANETs are described as the most frequent tumor of the appendix, this was not confirmed in our series, in which they only represented 28.6% of the cases; adenocarcinoma was the most frequent tumor (65.7%) among our sample.

scholarly journals A novel de novo DDX3X missense variant in a female with brachycephaly and intellectual disability: a case report

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Giada Moresco ◽  
Jole Costanza ◽  
Carlo Santaniello ◽  
Ornella Rondinone ◽  
Federico Grilli ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Clinical Presentation ◽  
De Novo ◽  
Clinical Signs ◽  
Missense Variant ◽  
Psychomotor Development ◽  
Helicase Domain ◽  
Protein Activity ◽  
Mrna Metabolism ◽  
Pathogenic Variants

Abstract Background De novo pathogenic variants in the DDX3X gene are reported to account for 1–3% of unexplained intellectual disability (ID) in females, leading to the rare disease known as DDX3X syndrome (MRXSSB, OMIM #300958). Besides ID, these patients manifest a variable clinical presentation, which includes neurological and behavioral defects, and abnormal brain MRIs. Case presentation We report a 10-year-old girl affected by delayed psychomotor development, delayed myelination, and polymicrogyria (PMG). We identified a novel de novo missense mutation in the DDX3X gene (c.625C > G) by whole exome sequencing (WES). The DDX3X gene encodes a DEAD-box ATP-dependent RNA-helicase broadly implicated in gene expression through regulation of mRNA metabolism. The identified mutation is located just upstream the helicase domain and is suggested to impair the protein activity, thus resulting in the altered translation of DDX3X-dependent mRNAs. The proband, presenting with the typical PMG phenotype related to the syndrome, does not show other clinical signs frequently reported in presence of missense DDX3X mutations that are associated with a most severe clinical presentation. In addition, she has brachycephaly, never described in female DDX3X patients, and macroglossia, that has never been associated with the syndrome. Conclusions This case expands the knowledge of DDX3X pathogenic variants and the associated DDX3X syndrome phenotypic spectrum.

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