scholarly journals Predicting coronary artery disease risk in firefighters – a cross-sectional study

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 701
Author(s):  
Jaron Ras ◽  
Lloyd Leach

Background: Firefighters are placed under severe cardiovascular load in performing active duty and, when carrying various coronary artery disease (CAD) risk factors, firefighters are predisposed to significant morbidity and mortality. Reducing the incidence of these risk factors is paramount. The purpose of this study is to determine the predictors of CAD risk.   Methods: This study used a quantitative, cross-sectional and correlational design. The researchers conveniently sampled 124 full-time firefighters from the City of Cape Town Fire and Rescue Service. A researcher-generated questionnaire was used to collect sociodemographic and CAD risk factors information, such as age, gender, ethnicity, family history of CAD, cigarette smoking and physical activity levels, and all research procedures were conducted according to the American College of Sports Medicine guidelines. Data collection took place between September and November 2019. Linear and logistic regression were used to determine the relationship between the various CAD risk factors and the predictors of CAD risk.   Results: Age was a significant predictor of hypertension (p <0.01), dyslipidemia (p <0.01), diabetes (p <0.01), obesity (p <0.01) and central obesity (p <0.01). Gender was a significant predictor of obesity, central obesity and cigarette smoking (p <0.05). Waist circumference was a significant predictor of hypertension (p <0.01), dyslipidemia (p <0.01) and diabetes (p <0.05).   Conclusion: Age was a significant predictor of various modifiable CAD risk factors, including obesity, in both genders and all ethnicities. Attentive monitoring should be in place as firefighters age, along with behavioural modifications designed to reduce age-related increases in CAD risk factors.

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Jaron Ras ◽  
Lloyd Leach

Background: Over 45% of firefighter deaths are attributable to sudden cardiac death related to coronary artery disease (CAD), with many of these deaths attributed to comorbidities. The purpose of the study is to determine the prevalence of coronary artery disease (CAD) risk factors in firefighters in the City of Cape Town (CoCT).Design and Methods: The study used a quantitative, cross-sectional and descriptive design. A total of 124 full-time firefighters were conveniently recruited between September and November 2019 from the City of Cape Town Fire and Rescue Service. Results: The most prevalent CAD risk factors among firefighters were hypertension (33.1%), obesity (37.1%), cigarette smoking (39.5%) and dyslipidaemia (40.3%). A total of 41.9% of firefighters were categorized as low-risk, 54.8% as moderate-risk, and 3.2% as high-risk for CAD.Conclusion: The majority of firefighters had at least one CAD risk factor, with older males having the highest prevalence of multiple CAD risk factors. Compared to other regions of the world, the (CoCT) firefighters have higher prevalence of dyslipidaemia and cigarette smoking. Preventative behavioural strategies and education on CAD should be promoted to mitigate the development of CAD.


2020 ◽  
Vol 9 (11) ◽  
pp. 5629
Author(s):  
MohammadAzhar Rashikh ◽  
AbdulmgeedFahhad H. Alruways ◽  
NemerAbdulaziz Alotaibi ◽  
AliAlhumaidi Alnufeie ◽  
YosefJazza D. Alshammari ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
pp. 360-370
Author(s):  
Jaron Ras ◽  
Lloyd Leach

Background: Many CAD risk factors occur concurrently, increasing the odds of the development of other risk factors, which is particularly seen in male and older firefighters. Objective: The purpose of this study was to determine the association and odds ratios between the various CAD risk factors in firefighters. Methods: This study used a quantitative, cross-sectional and correlational design. A total of 124 full-time firefighters, males and females, were conveniently recruited from the City of Cape Town Fire and Rescue Service. A researcher generated questionnaire was used to collect participant sociodemographic information, and all research procedures were conducted according to the ACSM guidelines. The study took place between September and November 2019. Results: There were significant associations between hypertension and age [χ2(1) = 18.0, p < 0.001, OR = 6.3 (95% CI: 2.6, 15.5)], hypertension and obesity [χ2(1) = 7.9, p = 0.005, OR = 3.0 (95% CI: 1.4, 6.6)], hypertension and diabetes [χ2(1) = 5.1, p = 0.040, OR = 4.0 (95% CI: 1.1, 14.8)], and hypertension and dyslipidaemia [χ2(1) = 8.5, p = 0.004, OR = 3.1 (95% CI: 1.4, 6.7)], family history and central obesity [χ2(1) = 3.9, p = 0.04, OR = 2.4 (95% CI: 0.9, 5.8)], and family history and central obesity [χ2(1) = 3.9, p = 0.04, OR = 2.4 (95% CI: 0.9, 5.8)]. Conclusion: Increased age, central obesity, hypertension and dyslipidaemia increased the odds of developing other major CAD risk factors, which was predominantly apparent in male firefighters of mixed ethnicity. The City of Cape Town Fire and Rescue Service should emphasize the mitigation of these major CAD risk factors through education and behavioural modification, especially as male firefighters aged.


2013 ◽  
Vol 131 (5) ◽  
pp. 296-300 ◽  
Author(s):  
Antonio Ivo Moritz Neto ◽  
Joel Rolim de Moura Junior ◽  
Darlene Camati Persuhn

CONTEXT AND OBJECTIVE: Atherosclerotic disease is the leading cause of death in Brazil. It is a complex disease and its prevention involves identification and control of risk factors. Moderately increased plasma homocysteine concentration (hyperhomocysteinemia) has been considered to be a risk factor for several vascular diseases. Mutations in the methylenetetrahydrofolate reductase (MTHFR) enzyme, which is involved in homocysteine metabolism, have been investigated as potential vascular disease risk factors. G1793A polymorphism was described in 2002 and there are few studies analyzing its involvement in diseases. The objective of this study was to investigate the prevalence of G1793A polymorphism in subjects with early coronary artery disease (CAD). DESIGN AND SETTING: Cross-sectional study with control group conducted at a private cardiology clinic and a molecular biology laboratory (Universidade do Vale do Itajaí). METHODS: We studied 74 early-onset CAD+ patients and 40 CAD- individuals with normal angiography results. DNA was extracted from blood samples. Molecular data were obtained via PCR/RFLP and agarose gel electrophoresis. RESULTS: The occurrence of G1793A heterozygotes was similar in the control (5%) and test (6.25%) groups, thus showing that in the population studied there was no correlation between the marker and occurrences of early CAD. There was also no association between the polymorphism and the risk factors for atherosclerosis. CONCLUSIONS: The frequency of the 1793A allele in the test group (3.4%) was similar to what was found in the control individuals (2.5%). There was no correlation between G1793A polymorphism and occurrences of early CAD in this population.


2020 ◽  
Vol 27 (12) ◽  
pp. 2591-2595
Author(s):  
Naeem Hameed ◽  
Shahid Abbas ◽  
Faisal Ali ◽  
Muhammad Akram ◽  
Shahid Iqbal ◽  
...  

Objectives: Objective of this study was to find out the prevalence of risk factors for coronary artery disease in very important group of population who are expected to have sedentary lifestyle. Study Design: Cross-Sectional study. Setting: Faisalabad Institute of Cardiology, Faisalabad. Period: January 2015 to June 2017. Material & Methods: Officers from age of 25 years to 60 years and of either sex were enrolled in study. FLP, FBS, BP, weight and height were measured at FIC. Frequency of coronary artery disease risk factors including Diabetes, HTN, smoking, dyslipidemia, physical activity and obesity was noted considering diagnostic criteria. Results: Mean age was 40.86 ± 7.49, 84.4% (n=76) were male, 15.6% (n=14) were females, 11.1% (n=10) were diabetic, 88.9% (n=80) were non-diabetic, 4 were known case of ischemic heart disease with one having CABG. Smoking was present in 27.8%(n=25). Hypertension was found in 22.2%(n=20). LDL cholesterol was raised in 24.4%(n=22) officers. 46.7%(n=42) were having high BMI i.e.>25.  A high proportion was found to have sedentary lifestyle with 72.2%(n=65) being physically less active. Conclusion: Major conventional Risk factors for coronary artery disease are prevalent in young healthy judicial officers who were not patient of any significant disease.


2019 ◽  
Vol Volume 12 ◽  
pp. 63-70 ◽  
Author(s):  
Mohammed Ali Almalki ◽  
Maram Nader AlJishi ◽  
Maie Abdulrhman Khayat ◽  
Hotoun Fayez Bokhari ◽  
Ahmed Hussein Subki ◽  
...  

Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 605
Author(s):  
Hanna K. Al-Makhamreh ◽  
Mohammed Q. Al-Sabbagh ◽  
Ala’ E. Shaban ◽  
Abdelrahman F. Obiedat ◽  
Ayman J. Hammoudeh

Background and Objectives: Patients with AF are at increased risk for Coronary Artery Disease (CAD) owing to their shared etiologies and risk factors. This study aimed to assess the prevalence, cardiovascular risk factors, and used medications of CAD in AF patients. Materials and Methods: This retrospective, case-control study utilized data from the Jordanian Atrial Fibrillation (Jo-Fib) registry. Investigators collected clinical features, history of co-existing comorbidities, CHA2DS2-VASc, and HAS BLED scores for all AF patients aged >18 visiting 19 hospitals and 30 outpatient cardiology clinics. A multivariable binary logistic regression was used to asses for factors associated with higher odds of having CAD. Results: Out of 2000 patients with AF, 227 (11.35%) had CAD. Compared to the rest of the sample, those with CAD had significantly higher prevalence of hypertension (82.38%; p < 0.01), hypercholesterolemia (66.52%, p < 0.01), diabetes (56.83%, p < 0.01), and smoking (18.06%, p = 0.04). Patients with AF and CAD had higher use of anticoagulants/antiplatelet agents combination (p < 0.01) compared to the rest of the sample. Females had lower CAD risk than males (OR = 0.35, 95% CI: 0.24–0.50). AF Patients with dyslipidemia (OR = 2.5, 95% CI: 1.8–3.4), smoking (OR = 1.7, 95% CI: 1.1–2.6), higher CHA2DS2-VASc score (OR = 1.5, 95% CI: 1.4–1.7), and asymptomatic AF (OR = 1.9, 95% CI: 1.3–2.6) had higher risk for CAD. Conclusions: Owing to the increased prevalence of CAD in patients with AF, better control of cardiac risk factors is recommended for this special group. Future studies should investigate such interesting relationships to stratify CAD risk in AF patients. We believe that this study adds valuable information regarding the prevalence, epidemiological characteristics, and pharmacotherapy of CAD in patients with AF.


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