Case Report: Gollop-Wolfgang Complex in a 5 month old baby

Skeletal dysplasias are disorders associated with a generalized abnormality in the skeleton. The Gollop-Wolfgang complex (GWC) is a limb deficiency disorder and an unusual limb malformation with highly variable manifestations. Here we report an interesting case of a 5-month old male baby from India with Gollop-Wolfgang Complex showing bifurcation of the right femur, ectrodactyly of both feet, ectrodactyly of left hand, syndactyly of right hand and unusual presentation of bilateral fibular agenesis and caudal (Sacrococcygeal) agenesis. The etiology of GWC in this 5 month old male baby could possibly be attributed to spontaneous gene mutation. The clinical, radiographic findings and the unusual presentation are presented in detail

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Case Report: Gollop-Wolfgang Complex in a 5 month old baby

F1000Research ◽

10.12688/f1000research.5889.1 ◽

2014 ◽

Vol 3 ◽

pp. 315 ◽

Cited By ~ 1

Author(s):

Ihtesham A. Qureshi ◽

Rohit Kumar Gudepu ◽

Ravikanth Chava ◽

Sravya Emmani ◽

Syed Husain Asghar ◽

...

Keyword(s):

Case Report ◽

Consanguineous Marriage ◽

Interesting Case ◽

Unusual Presentation ◽

Radiographic Findings ◽

Left Hand ◽

Skeletal Dysplasias ◽

Male Baby ◽

The Right ◽

Limb Deficiency

Skeletal dysplasias are disorders associated with a generalized abnormality in the skeleton. The Gollop-Wolfgang complex (GWC) is a limb deficiency disorder and an unusual limb malformation with highly variable manifestations. Here we report the interesting case of a 5-month old male baby from India with Gollop-Wolfgang Complex showing bifurcation of the right femur, ectrodactyly of both feet, ectrodactyly of left hand, syndactyly of right hand and unusual presentation of bilateral fibular agenesis and caudal (Sacrococcygeal) agenesis. The etiology of GWC in this 5 month old male baby could possibly be attributed to spontaneous gene mutation due to consanguineous marriage of his parents. The clinical, radiographic findings and the unusual presentation are presented in detail.

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A case report of unilateral conductive hearing loss as a consequence of malignant sinonasal melanoma: the importance of completing a full clinical history and examination

The Egyptian Journal of Otolaryngology ◽

10.1186/s43163-020-00057-7 ◽

2020 ◽

Vol 36 (1) ◽

Author(s):

Victoria Blackabey ◽

Olivia Kenyon ◽

Rishi Talwar

Keyword(s):

Hearing Loss ◽

Case Report ◽

Clinical Symptoms ◽

Symptomatic Relief ◽

Clinical History ◽

Histological Diagnosis ◽

Unusual Presentation ◽

Sinus Surgery ◽

Cancer Management ◽

The Right

Abstract Background Sinonasal melanoma is a rare head and neck tumour. It is associated with a poor prognosis, high rates of loco-regional recurrence and distant metastasis. Treatment of the disease is therefore complicated, and because of limited data regarding the cancer, management is frequently tailored to the individual patient. We describe an unusual presentation of sinonasal melanoma with relevant histology, radiology and clinical photography. Case presentation The case report describes the presentation of a 64-year-old man to the Ear, Nose and Throat department with progressive right-sided hearing loss. A thorough history highlighted other clinical symptoms including unilateral nasal obstruction and epistaxis. Clinical examination showed a right middle ear effusion with a polypoidal lesion in the right nasal cavity. Relevant imaging demonstrated a destructive process that required further assessment. An endoscopic sinus procedure was performed to obtain histological diagnosis as well as providing symptomatic relief. Histology confirmed malignant mucosal melanoma. The patient underwent maxillectomy and orbital exenteration (due to further progression of disease) at a tertiary centre with a plan for subsequent immunotherapy. This however has been delayed due to further surgery to excise a metastatic lesion to the right femur. Conclusions This case report highlights the importance of a thorough clinical history and examination. An unusual presentation of a sinonasal tumour can easily be missed leading to a significant delay in treatment. The case report also describes the use of functional endoscopic sinus surgery in order to obtain histological diagnosis and to debulk the tumour, providing symptomatic relief. The current literature regarding management will be discussed as well as current developments guiding future treatment.

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Excellent Functionality Despite Clinico-Radiological Deformity in Osteomyelitis Variolosa - A Case Report

The Open Orthopaedics Journal ◽

10.2174/1874325001509010114 ◽

2015 ◽

Vol 9 (1) ◽

pp. 114-119

Author(s):

Aakash Mugalur ◽

Sunil M Shahane ◽

Ashwin Samant ◽

Aditya C Pathak ◽

Rajeev Reddy

Keyword(s):

Case Report ◽

Elbow Joint ◽

Cortical Thickening ◽

Diagnostic Challenge ◽

Left Hand ◽

Articular Surfaces ◽

The World ◽

Radiological Abnormality ◽

Endemic Areas ◽

The Right

Despite the eradication of smallpox from the world in 1980 the osteo-articular sequelae of smallpox are still occasionally noticed in previously endemic areas. The sequelae of osteomyelitis variolosa may raise a diagnostic challenge to the untrained eyes of the surgeon. We present a case of “osteomyelitis variolosa” in a 70 years old patient. The patient had bilateral dislocation of the elbow joint with multidirectional instability. There was distortion of the articular surfaces and ankylosis of the bilateral proximal radio-ulnar joint. Hypoplasia of the right ulna with short fourth and fifth metacarpals of the left hand and hypoplasia of right fourth metacarpal with cortical thickening was noted radiologically. The patient had minimal disability of his elbows despite the striking radiological abnormality and was functionally independent.

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Bilateral Opponens Replacement in Post Polio Thenar Paralysis, Using Different Techniques. A Case Report.

HAND ◽

10.1016/s0072-968x(83)80019-9 ◽

1983 ◽

Vol os-15 (2) ◽

pp. 221-222 ◽

Cited By ~ 1

Author(s):

J. G. Andersen ◽

J. W. Brandsma

Keyword(s):

Case Report ◽

Ring Finger ◽

Flexor Digitorum Superficialis ◽

Left Hand ◽

Right Hand ◽

Abductor Digiti Minimi ◽

The Right ◽

Flexor Digitorum

A patient is presented with bilateral thenar paralysis, due to poliomyelitis. On the right hand a successful abductor digiti minimi transfer was performed. On the left hand weakness of the hypothenar muscles prevented a good result. Subsequently an opponens replacement, using flexor digitorum superficialis from the ring finger, yielded a good result.

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Recurrent transient heading disorientation heralding acute posterior cerebral artery (PCA) infarction

BMJ Neurology Open ◽

10.1136/bmjno-2019-000009 ◽

2019 ◽

Vol 1 (1) ◽

pp. e000009

Author(s):

Yong Chuan Chee ◽

Beng Hooi Ong

Keyword(s):

Case Report ◽

Cerebral Infarction ◽

Cerebral Artery ◽

Transient Ischaemic Attack ◽

Posterior Cerebral Artery ◽

Underlying Mechanism ◽

Unusual Presentation ◽

Topographical Disorientation ◽

Ischaemic Attack ◽

The Right

ObjectiveHeading disorientation is a type of pure topographical disorientation. Reported cases have been very few and its underlying mechanism remains unclear. We report an unusual presentation of a 60-year-old man with recurrent transient heading disorientation heralding an acute posterior cerebral artery infarction.DesignCase report.ConclusionAcquired injury to the right retro-splenial region can result in a specific variant of topographical disorientation known as heading disorientation that may present as an atypical transient ischaemic attack-like symptom heralding acute cerebral infarction.

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Unusual presentation of late-onset disseminated staphylococcal sepsis in a preterm infant

BMJ Case Reports ◽

10.1136/bcr-2018-226325 ◽

2019 ◽

Vol 12 (3) ◽

pp. e226325 ◽

Cited By ~ 1

Author(s):

Shahzad Gul Khattak ◽

Ian Dady ◽

Devdeep Mukherjee

Keyword(s):

Late Onset ◽

Whole Body ◽

Whole Body Mri ◽

Left Hand ◽

Non Invasive ◽

Male Baby ◽

Left Elbow ◽

The Right ◽

Panton Valentine Leukocidin ◽

Rule Out

An ex-30-week gestation, preterm male baby was admitted to a tertiary neonatal unit and noted to have increased ventilator requirements and diagnosed with sepsis. The baby also developed an abscess over the left elbow and over the xiphisternum along with a decrease in movement of the left hand and the right leg. Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (SA) was isolated from the blood culture. A whole body MRI showed disseminated abscess with multiple foci in the lung, left elbow and over the xiphisternum. Disseminated sepsis with multiple septic foci has not been previously reported in neonates. We would like to highlight the fact that sepsis due to PVL toxin-producing SA can cause significant morbidity and mortality in neonates. Proper screening should be done to rule out septic foci in neonates. MRI is a good non-invasive investigation to document septic foci in a neonate and rule out multiorgan involvement.

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Right Homonymous Hemianopia: A Clinical Case Report of Schizencephaly

Case Reports in Ophthalmology ◽

10.1159/000443323 ◽

2016 ◽

Vol 7 (1) ◽

pp. 16-20 ◽

Cited By ~ 5

Author(s):

Arminda Neves ◽

Fausto Carvalheira ◽

Joana Campos ◽

Pedro Alfaiate ◽

António Campos ◽

...

Keyword(s):

Case Report ◽

Brain Parenchyma ◽

Interesting Case ◽

Homonymous Hemianopia ◽

Fiber Layer ◽

Left Brain ◽

Corrected Visual Acuity ◽

The Right ◽

Clinical Records ◽

Automated Static Perimetry

Purpose: To report a case of a 56-year-old male with right homonymous hemianopia. Methods: Retrospective descriptive study of a case report based on information from clinical records, patient observation and analysis of complementary diagnostic tests. Results: An asymptomatic 56-year-old male presented to our hospital for a routine ophthalmic examination. The best-corrected visual acuity was 20/20 in the right eye (RE) and in the left eye (LE). Pupillary function, intraocular pressure, external segment examinations and slit-lamp biomicroscopy were normal, bilaterally. Fundoscopy showed a cup-to-disc (C/D) ratio in the RE of 0.3 and of 0.4 in the LE. Retinal nerve fiber layer (RNFL) thickness measured by spectral domain optical coherence tomography revealed thinning of the superior, temporal and nasal RNFL in the RE and thinning of the superior, inferior and temporal RNFL in the LE. Automated static perimetry showed right homonymous hemianopia. Brain computed tomography (CT) showed an open-lip schizencephaly with a significant reduction of the left brain parenchyma. Conclusions: Despite the large visual defect, the patient was unaware of it and had an active professional life. This is an interesting case because despite the extensive morphological abnormalities seen on brain CT there is a relatively small functional repercussion.

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Adnexal Torsion after Isolated Salpingeal Torsion: An Undesired Complication of Conservative Management: A Case Report

Journal of Family & Reproductive Health ◽

10.18502/jfrh.v14i1.3789 ◽

2020 ◽

Author(s):

Eniola R. Ibirogba ◽

Faheema Abduljalil Alshehabi ◽

Afeefa Ashfaq Konchwalla ◽

Mohammed Sobhy Badr Sobei ◽

Amal Hassan Hassan Ismail

Keyword(s):

Case Report ◽

Fallopian Tube ◽

Conservative Management ◽

Clinical Laboratory ◽

Reproductive Age ◽

Adnexal Torsion ◽

Lower Quadrant ◽

Radiographic Findings ◽

Clinically Significant ◽

The Right

Objective: Isolated salpingeal torsion (IST) is a rare cause of acute abdomen in women of the reproductive age group. The lack of pathognomonic clinical, laboratory or radiographic findings makes early diagnosis a challenge. We describe a case of IST in a 13-year-old who suffered from a repeat torsion following initial conservative management. Case Report: A 13-year-old girl presented with acute right lower quadrant abdominal pain of insidious onset. Her past medical history was non-contributory and her initial workup was unremarkable. Exploratory laparoscopy subsequently revealed isolated torsion of the right fallopian tube which was detorted. She presented 10 months later with similar complaints and further workup demonstrated right adnexal torsion which was confirmed by laparoscopy; salpingo-oophorectomy was necessary due to gangrenous necrosis. Conclusion: Conservative management of fallopian tube torsion confers the advantage of fertility preservation but the risk of repeat torsion remains clinically significant.

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An Interesting Case Report of Frontal Sinus Keratocyst

Journal of Molecular Biology Research ◽

10.5539/jmbr.v9n1p100 ◽

2019 ◽

Vol 9 (1) ◽

pp. 100

Author(s):

Alireza Mohebbi ◽

Mohammad Aghajanpour

Keyword(s):

Case Report ◽

Surgical Resection ◽

Frontal Sinus ◽

Interesting Case ◽

Ophthalmological Examination ◽

Eyelid Edema ◽

Complete Surgical Resection ◽

Orbital Wall ◽

History Of ◽

The Right

Purpose: To report an unusual case of frontal sinus keratocyst. Case Report: A 31 year old woman presented with a history of swollen right eye and visual field impairment. The ophthalmological examination revealed right superior eyelid edema and some degrees of proptosis. CT scan with iodine injection evidenced the opacification of the right frontal sinus with superior orbital wall lysis. Complete endoscopic surgical resection of a mass containing foul smelling keratin material was performed via Draf type III. The patient became symptomatic after 6 years. Imaging studies showed neo- osteogenesis in the far lateral end of right frontal sinus. Frontal trephination was done and the remnant of keratocyst was removed and the septum interfacing the cell and the right frontal sinus was walled down entirely. Conclusion: Although frontal sinus keratocyst is benign but can spread to the surrounding structures leading to several complications. Therefore, complete surgical resection is necessary to avoid recurrence.

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