scholarly journals Size, Concentration and Incubation Time Dependence of Gold Nanoparticle Uptake into Pancreas Cancer Cells and its Future Application to X-ray Drug Delivery System

2011 ◽  
Vol 52 (1) ◽  
pp. 103-109 ◽  
Author(s):  
Jade Dungao TRONO ◽  
Kazue MIZUNO ◽  
Noritaka YUSA ◽  
Takehisa MATSUKAWA ◽  
Kazuhito YOKOYAMA ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Time Dependence ◽  
Cancer Cells ◽  
Gold Nanoparticle ◽  
Drug Delivery System ◽  
Delivery System ◽  
Incubation Time ◽  
Pancreas Cancer ◽  
Future Application ◽  
X Ray

scholarly journals pH and redox dual-sensitive drug delivery system constructed based on fluorescent carbon dots

RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 2656-2663
Author(s):  
Boye Zhang ◽  
Qianqian Duan ◽  
Yi Li ◽  
Jianming Wang ◽  
Wendong Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Ph Responsive ◽  
Charge Reversal ◽  
Fluorescent Carbon Dots

The system is pH-responsive and redox-controlled release. And the charge reversal and size transitions of the system can enhance the targeted ability. Moreover, the system can recognize the cancer cells by the fluorescence imaging.

Design and Function of Engineered Protein Nanocages as a Drug Delivery System for Targeting Pancreatic Cancer Cells via Neuropilin-1

2015 ◽  
Vol 12 (5) ◽  
pp. 1422-1430 ◽  
Author(s):  
Masaharu Murata ◽  
Sayoko Narahara ◽  
Takahito Kawano ◽  
Nobuhito Hamano ◽  
Jing Shu Piao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pancreatic Cancer Cells ◽  
Neuropilin 1 ◽  
And Function

An Acid-Triggered Degradable and Fluorescent Nanoscale Drug Delivery System with Enhanced Cytotoxicity to Cancer Cells

2015 ◽  
Vol 16 (8) ◽  
pp. 2444-2454 ◽  
Author(s):  
Jinxia An ◽  
Xiaomei Dai ◽  
Zhongming Wu ◽  
Yu Zhao ◽  
Zhentan Lu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System

scholarly journals Self-assembled pH-responsive supramolecular hydrogel for hydrophobic drug delivery

RSC Advances ◽  
2018 ◽  
Vol 8 (55) ◽  
pp. 31581-31587 ◽  
Author(s):  
Lin Wang ◽  
Xuefeng Shi ◽  
Jian Zhang ◽  
Yuejun Zhu ◽  
Jinben Wang
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Hydrophobic Drug ◽  
Ph Responsive ◽  
Supramolecular Hydrogel ◽  
Self Assembled

Supramolecular hydrogel, AGC16/NTS, was used to encapsulate hydrophobic drug curcumin (Cur), constructing a pH-responsive drug delivery system; the uptake of released Cur by cancer cells also occurred.

Pseudo-branched polyester copolymer: an efficient drug delivery system to treat cancer

2020 ◽  
Vol 8 (6) ◽  
pp. 1592-1603
Author(s):  
Zachary Shaw ◽  
Arth Patel ◽  
Thai Butcher ◽  
Tuhina Banerjee ◽  
Ren Bean ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Diagnosis And Treatment ◽  
Therapeutic Drug

New aliphatic pseudo-branched polyester copolymers are synthesized from diethylmalonate. The formulated nanomedicine successfully encapsulates therapeutic drug in higher dosage and deliver specifically to cancer cells for diagnosis and treatment.

Using Magnetic and Photic Stimuli-Responsive Liposomes to Serve Up Chemotherapy Drugs to Cancer Cells

2020 ◽  
Vol 16 (6) ◽  
pp. 867-875
Author(s):  
Junlin Li ◽  
Lingyun Hao ◽  
Xiaojuan Zhang ◽  
Qing Lin ◽  
Dong Liang
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Uv Light ◽  
Atomic Ratio ◽  
Solution Temperature ◽  
Photothermal Effect ◽  
Chemotherapy Drugs

Liposome is a traditional drug-delivery system and most novel studies have focused on its drug release function. In this paper, a new drug-delivery system based on liposomes was prepared, which contains hydrophobic FeAg alloy nanoparticles (FeAgNPs) in their lipid bilayer and berberine as test drug in their middle water phase. The size of AgFe-Ls was about 200 nm, the encapsulation efficiency of drugs was 35% and the lower critical solution temperature (LCST) of AgFe-Ls was about 41.96 °C. FeAgNPs in the AgFe-Ls had a 1:1 iron-to-silver atomic ratio with both optical and superparamagnetic properties. The photothermal effect and magnetocaloric effect of FeAgNPs could serve up both photo-stimulated and magnetic- stimulated drug release to liposomes. Release experiments results showed that AgFe-Ls could easily release berberine when stimulated by UV light (45% drug release at 20 min) or alternating current electromagnetic field (AMF) (80% drug release at 4 h). AgFe-Ls with both photo-controlled and magnetic-controlled drug release functions are promising to serve up chemotherapy drugs to cancer cells.

Reduction-responsive gold-nanoparticle-conjugated Pluronic micelles: an effective anti-cancer drug delivery system

2012 ◽  
Vol 22 (36) ◽  
pp. 18864 ◽  
Author(s):  
Youhua Tao ◽  
Jiangfeng Han ◽  
Chunting Ye ◽  
Tima Thomas ◽  
Huanyu Dou
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticle ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cancer Drug Delivery

Enzyme-triggered delivery of chlorambucil from conjugates based on the cell-penetrating peptide BP16

2015 ◽  
Vol 13 (5) ◽  
pp. 1470-1480 ◽  
Author(s):  
Marta Soler ◽  
Marta González-Bártulos ◽  
Eduard Figueras ◽  
Xavi Ribas ◽  
Miquel Costas ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Cells ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Uptake And Release

The combination of the cell-penetrating peptide BP16 with the enzymatic cleavable sequence Gly-Phe-Leu-Gly constitutes a drug delivery system for the effective uptake and release of chlorambucil in cancer cells.

Preparation of the Nano-Hydroxyapatite/Chitosan/Konjac Glucomannan Composite as a Novel Degradable Drug Delivery System

2008 ◽  
Vol 569 ◽  
pp. 357-360
Author(s):  
Gang Zhou ◽  
Yu Bao Li ◽  
Soo Wohn Lee
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Konjac Glucomannan ◽  
In Vitro Test ◽  
X Ray Diffraction ◽  
X Ray ◽  
Before And After ◽  
Vitro Test

Nano-hydroxyapatite (n-HA)/chitosan (CS)/konjac glucomannan (KGM) composite was prepared by integrating composition and molding. Then, X-ray diffraction (XRD) and scanning electron microscopy (SEM) were used to analyze the physical, chemical and degradable properties of the composite before and after in simulated body fluid (SBF). Moreover, study in vitro test for drug delivery revealed that the amount of released pentoxifylline (1-[5-oxohexyl]-3,7-dimethylxanthine)(PTX) reached a plateau and equaled 80% of the drug loaded in an implant. The newly develop n-HA/CS/KGM composite may serve as a good degradable biomaterial for implantable drug delivery system (IDDS) in bone tissue engineering.

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