scholarly journals Relationship between COVID-19 Infection and ABO Blood Groups Differences: A Tertiary Centre Experience in Al-Madinah, Saudi Arabia

2021 ◽  
Vol 9 (2) ◽  
pp. 36-42
Author(s):  
Abdulhalem A. Jan ◽  
Ahmed M. Aljeraisi ◽  
Abdullah M. Algarni ◽  
Mohammed A. Almozini ◽  
Nashwa A. Alsyed ◽  
...  
2019 ◽  
Vol 7 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Diana Mostafa ◽  
Essam I. Elkhatat ◽  
Pradeep Koppolu ◽  
Muna Mahgoub ◽  
Esam Dhaifullah ◽  
...  

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.


Bionatura ◽  
2020 ◽  
Vol 5 (2) ◽  
pp. 1142-1149
Author(s):  
Raghad S. Mouhamad ◽  
Khlood Abedalelah Al-Khafaji ◽  
Risala H. Allami ◽  
Michael Alabboud ◽  
Maha Hameed Abdulla ◽  
...  

The novel SARS-CoV-2 belongs to the beta coronaviruses and causes a severe pandemic disease named as COVID-19. In late December 2019. WHO situation reports on 11 March 2020, declared that COVID-19 a pandemic due to its global spread. All Arab countries have reported COVID-19 cases. The confirmed cases of COVID-19 pandemic in Arab gulf countries were reported in the United Arab Emirates, Iraq, Bahrain, Oman, Qatar, Kuwait, and Saudi Arabia, respectively. The fatality case rates in Gulf Countries are less than 1% in Oman, UAE, Kuwait, Bahrain, and Saudi Arabia, yet it hits 7.5% in Iraq. In this manuscript, we try to interpret the pandemic statistically in gulf countries, especially in Iraq. Additionally, the distribution of COVID-19 confirmed cases based on ABO blood groups were investigated. Epidemiological analyses revealed that a decreased risk of infection was attributed to blood group O compared to non-O blood groups, whereas people with the A and A.B. blood groups showed the highest risk for COVID-19 infection. Besides, high risk for diabetes, cardiovascular disease, blood clotting, and interleukin secretion was also related to blood groups in different orders. Accordingly, patients with a specific blood group that are associate with the above diseases should be under strict medical surveillance when infected with COVID-19 to reduce complications and severity. This study provides further confirmation for the previously reported correlation between the ABO blood groups and the susceptibility to COVID-19 infection.


Medicine ◽  
2021 ◽  
Vol 100 (30) ◽  
pp. e26738
Author(s):  
Mohammed Badedi ◽  
Awaji Alnami ◽  
Hussain Darraj ◽  
Anas Alrajhi ◽  
Dhayf-Alrahman Mutawwam ◽  
...  

2017 ◽  
Vol 5 (1) ◽  
pp. 2917-2920 ◽  
Author(s):  
AbdullahMohammed. AlBilali. ◽  
◽  
OmarBadr. AlFraidy. ◽  
HatemHussein. AlHarbi. ◽  
SultanJameel. Mhros. ◽  
...  

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Ali H. Ad’hiah ◽  
Risala H. Allami ◽  
Raghdan H. Mohsin ◽  
Maha H. Abdullah ◽  
Ali J. R. AL-Sa’ady ◽  
...  

Abstract Background Susceptibility to the pandemic coronavirus disease 2019 (COVID-19) has recently been associated with ABO blood groups in patients of different ethnicities. This study sought to understand the genetic association of this polymorphic system with risk of disease in Iraqi patients. Two outcomes of COVID-19, recovery and death, were also explored. ABO blood groups were determined in 300 hospitalized COVID-19 Iraqi patients (159 under therapy, 104 recovered, and 37 deceased) and 595 healthy blood donors. The detection kit for 2019 novel coronavirus (2019-nCoV) RNA (PCR-Fluorescence Probing) was used in the diagnosis of disease. Results Mean age was significantly increased in patients compared to controls (49.8 ± 11.7 vs. 28.9 ± 6.6 years; p < 0.001). A similar observation was made in recovered (42.1 ± 10.4 vs. 28.9 ± 6.6 years; p < 0.001) and deceased (53.6 ± 9.7 vs. 28.9 ± 6.6 years; p < 0.001) cases. The mean age was also significantly increased in deceased cases compared to recovered cases (53.6 ± 9.7 vs. 42.1 ± 10.4 years; p < 0.001). There were gender-dependent differences in COVID-19 prevalence. The percentage of COVID-19 was higher in males than in females (all cases: 59.7 vs. 40.3%; recovered cases: 55.8 vs. 44.2%). Such male-gender preponderance was more pronounced in deceased cases (67.6 vs. 32.4%). Logistic regression analysis revealed that groups AB and B + AB were significantly associated with increased risk to develop COVID-19 (OR = 3.10; 95% CI 1.59–6.05; pc = 0.007 and OR = 2.16; 95% CI 1.28–3.63; pc = 0.028, respectively). No ABO-associated risk was observed in recovered cases. On the contrary, groups A (OR = 14.60; 95% CI 2.85–74.88; pc = 0.007), AB (OR = 12.92; 95% CI 2.11–79.29; pc = 0.042), A + AB (OR = 14.67; 95% CI 2.98–72.33; pc = 0.007), and A + B + AB (OR = 9.67; 95% CI 2.02–46.24; pc = 0.035) were associated with increased risk of death in deceased cases. Conclusions The findings of this study suggest that group AB may be a susceptibility biomarker for COVID-19, while group A may be associated with increased risk of death.


2015 ◽  
Vol 67 ◽  
pp. 485-489 ◽  
Author(s):  
Julaluk Noiphung ◽  
Kwanrutai Talalak ◽  
Irin Hongwarittorrn ◽  
Naricha Pupinyo ◽  
Pannawich Thirabowonkitphithan ◽  
...  

Blood ◽  
1982 ◽  
Vol 59 (6) ◽  
pp. 1286-1291 ◽  
Author(s):  
H Ludwig ◽  
W Mayr

Abstract An up-dated survey of the information pertaining to the role of genetic factors in susceptibility to multiple myeloma is attempted. Our own results include the HLA-A, B, and C types in 68 patients, the G1m and Km allotypes in 86 patients, and the frequencies of ABO blood groups in 126 patients with multiple myeloma. The allotype G1m(x) was significantly (p less than 0.05) more frequent in the patient group. Since the results in the literature on a possible HLA association have been inconsistent, all relevant available data were combined for an assessment of 379 patients versus 5041 controls. In this comparatively large patient group, the previously reported increase of HLA-4c (HLA-B5 + B18 + Bw35) complex could be confirmed and identified as a weak (RR = 1.7) but significant (p less than 0.05) association of susceptibility to multiple myeloma with HLA-B5. Evaluation of G1m allotypes in the combined sample of 258 patients and 4550 controls and Km in 179 and 2457, respectively yielded no significant differences.


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