The epidemiological plateau of Corona virus in Gulf countries: a descriptive statistics study

The novel SARS-CoV-2 belongs to the beta coronaviruses and causes a severe pandemic disease named as COVID-19. In late December 2019. WHO situation reports on 11 March 2020, declared that COVID-19 a pandemic due to its global spread. All Arab countries have reported COVID-19 cases. The confirmed cases of COVID-19 pandemic in Arab gulf countries were reported in the United Arab Emirates, Iraq, Bahrain, Oman, Qatar, Kuwait, and Saudi Arabia, respectively. The fatality case rates in Gulf Countries are less than 1% in Oman, UAE, Kuwait, Bahrain, and Saudi Arabia, yet it hits 7.5% in Iraq. In this manuscript, we try to interpret the pandemic statistically in gulf countries, especially in Iraq. Additionally, the distribution of COVID-19 confirmed cases based on ABO blood groups were investigated. Epidemiological analyses revealed that a decreased risk of infection was attributed to blood group O compared to non-O blood groups, whereas people with the A and A.B. blood groups showed the highest risk for COVID-19 infection. Besides, high risk for diabetes, cardiovascular disease, blood clotting, and interleukin secretion was also related to blood groups in different orders. Accordingly, patients with a specific blood group that are associate with the above diseases should be under strict medical surveillance when infected with COVID-19 to reduce complications and severity. This study provides further confirmation for the previously reported correlation between the ABO blood groups and the susceptibility to COVID-19 infection.

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Correlation of ABO Blood Groups and Rh Factor with The Severity of Generalized Chronic Periodontitis: Across Sectional Study in Riyadh, Saudi Arabia

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2019.044 ◽

2019 ◽

Vol 7 (4) ◽

pp. 617-622 ◽

Cited By ~ 2

Author(s):

Diana Mostafa ◽

Essam I. Elkhatat ◽

Pradeep Koppolu ◽

Muna Mahgoub ◽

Esam Dhaifullah ◽

...

Keyword(s):

Saudi Arabia ◽

Blood Group ◽

Chronic Periodontitis ◽

Periodontal Diseases ◽

Blood Groups ◽

Blood Group Antigens ◽

Abo Blood Groups ◽

Sectional Study ◽

Cross Sectional ◽

Group I

BACKGROUND: The development of periodontal diseases depends on the presence of causative microorganisms, host immunity and risk factors. Although variability present among the types of periodontal diseases, all are represented to a shared interaction between host and bacteria. ABO blood groups are the most investigated erythrocyte antigen system. However, limited investigations have been conducted to explore the alliance between ABO blood groups and periodontal diseases. AIM: Our purpose was to explore any possible association between the severity of chronic periodontitis with ABO blood groups and Rh factor. METHODS: A cross-sectional study was carried out on 205 patients out of 1126 generalised chronic periodontitis patients (GCP) who were referred to Al-Farabi Colleges, Riyadh, Saudi Arabia. They were categorized into; group I (mild), group II (moderate) and group III (sever). RESULTS: The patients with blood group O were at a greater risk to develop GCP irrespective of its severity, followed by those with blood group A, B, and AB. The dispensation of the Rh factor in all groups exhibited a significantly greater distribution of Rh positive. CONCLUSION: Genetic factors such as ABO blood group antigens may act as a risk influencer that affects the progression and severity of the chronic periodontitis.

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Distribution of ABO blood groups and association to low risk of COVID-19 infection in patients

10.21203/rs.3.rs-32315/v1 ◽

2020 ◽

Author(s):

Minfei Peng ◽

Shigao Huang ◽

Shitu Zhu ◽

Chaochao Chen ◽

Jiajia Qin ◽

...

Keyword(s):

Blood Group ◽

Lower Risk ◽

Blood Groups ◽

Low Risk ◽

Blood Type ◽

The Novel ◽

Abo Blood Groups ◽

Susceptible Population ◽

Novel Coronavirus ◽

Group Distribution

Abstract Background Since December 2019, the novel coronavirus pandemic (COVID-19) has become a global health emergency. To date, studies on the correlation between ABO blood groups and COVID-19 infected risk had rarely reported. This study aimed to describe the ABO blood groups distribution and association to low risk of COVID-19 infection for effectively concerning about the susceptible population. Methods We included 138 COVID-19 diagnosed patients and 82 non- COVID-19 patients between January 21 and February 20, 2020.We compared ABO blood group distribution, gender distribution and correlation analysis in Severe, Non-severe and Non-COVID19 patients, and analyzed the laboratory indexes of type O and non-type O groups in COVID19 patients. Results The laboratory results were significantly difference between type O and non-type O COVID19 patients (P < 0.05). Patients with blood type O had lower risk of severe COVID-19 infection (χ2 = 4.066, p = 0.044, OR = 0.380), and especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection (p = 0.049). Conclusion Patients with the blood group of type O had relatively lower risk of COVID19 infection, especially, female with the type O blood had lower risk in deteriorating severe COVID19 infection. We should concern more to the patients with non-type O blood to minimize the risk of COVID19 infection.

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Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

PLoS ONE ◽

10.1371/journal.pone.0249252 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0249252

Author(s):

Reaz Mahmud ◽

Mohammad Aftab Rassel ◽

Farhana Binte Monayem ◽

S. K. Jakaria Been Sayeed ◽

Md Shahidul Islam ◽

...

Keyword(s):

Blood Group ◽

Blood Groups ◽

Abo Blood Groups ◽

Duration Of Symptoms ◽

Presenting Symptoms ◽

Blood Group A ◽

Group I ◽

Significant Difference ◽

Group A ◽

Group Ii

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.

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DISTRIBUTION OF ABO AND RH (D) BLOOD GROUPS AMONG BLOOD DONORS IN DISTRICT MARDAN, PAKISTAN

Journal of Saidu Medical College, Swat ◽

10.52206/jsmc.2013.3.2.318-322 ◽

1969 ◽

Vol 3 (2) ◽

pp. 318-322

Author(s):

MUHAMMAD KHALID ◽

NAILA ASLAM ◽

MUHAMMAD SIYAR ◽

RASHID AHMAD

Keyword(s):

Blood Group ◽

Blood Donors ◽

Local Community ◽

Healthy Adult ◽

Blood Groups ◽

Abo Blood Groups ◽

Cross Sectional ◽

Group B ◽

Abo Blood Grouping ◽

Blood Grouping

OBJECTIVE: To find out the distribution of ABO and Rh (D) blood groups among blood donors in districtMardan and to help transfusion services in the area.STUDY DESIGN: Cross sectional descriptive study.MATERIALS AND METHODS: The study was conducted in DHQ Hospital Mardan from 1st January2012 to 31st December 2012. A total of 2893 healthy adult, blood donors (both volunteer and directed) fromdistrict Mardan were included. Two ml of blood anti-coagulated with EDTA was taken and both ABO andRh (D) blood groups were determined using commercially available anti-sera of Biolaboratories. Thedistribution ofABO and Rh blood groups in the local community were then calculated.RESULTS: Among ABO blood groups “ B” (27.97%) was the most prevalent, followed by “0” (27.93%),“ A” (24.75%) and “ AB” (19.36%). Group Rh positive (94.30%) was more prevalent than Rh negative(5.70%). Similarly 0+ve (26.65%) was most frequent followed by B+ve (26.17%), A+ve (23.16%), AB+ve(18.32%), B've(1.80%),Ave(l.59%),O ve( 1.28%) and ABve( 1.04%).CONCLUSION: Blood group 'B' was most frequent among the ABO blood groups and Rh (D) positiveamong Rh blood groups while0+vewas the most frequent blood group in the study population.KEYWORDS: ABO Blood grouping, Rh (D) blood grouping, Mardan.

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Prevalence of ABO blood groups in patients with haematological malignancies: a retrospective study

Hematology & Transfusion International Journal ◽

10.15406/htij.2020.08.00215 ◽

2020 ◽

Vol 8 (1) ◽

pp. 13-17

Author(s):

Ashwin Mathew ◽

Kirana Pailoor, ◽

Konchady Deepthi ◽

Suresh Shenoy

Keyword(s):

Sex Ratio ◽

Blood Group ◽

Haematological Malignancy ◽

Geographical Location ◽

Blood Groups ◽

Blood Type ◽

Haematological Malignancies ◽

Abo Blood Groups ◽

College Hospital ◽

And Gender

Background: The pattern and distribution of Haematological malignancies vary depending on age, sex and geographical location. Studies on the association between Haematological cancers and ABO blood types have been largely conflicting. The objective of our study was to determine the distribution of ABO blood groups among patients with Haematological malignancies and to correlate with age and gender. Materials and Methods: This was a chart based observational descriptive study involving the review of records of 85 patients with various Haematological malignancies in Father Muller Medical College Hospital for a period of two years from July 2017- June 2019. Age, gender, malignant condition, ABO and Rh blood group were collected for each case. Data was analyzed statistically by frequency and percentage. Results: The peak age incidence for various Haematological malignancies was in the fifth and sixth decades of life with a mean age of 47.The male to female sex ratio was almost 1:1. Majority of the patients were of the O blood group and an association of O blood group with various hematological malignancies with male preponderance was noted. Altogether, Leukemias were the most common Haematological malignancy observed in this study. Conclusion: The distribution, age and sex ratio of Haematological malignancies in our study was comparable to those reported by other authors with Acute Myeloid Leukemia (AML) being the most common Haematological malignancy in our environment. There was no significant association between Haematological cancers and ABO blood type of the patients, but probably individuals with O Rh positive blood group are more prone to

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Assessing ABO/Rh Blood Group Frequency and Association with Asymptomatic Malaria among Blood Donors Attending Arba Minch Blood Bank, South Ethiopia

Malaria Research and Treatment ◽

10.1155/2016/8043768 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Getaneh Alemu ◽

Mohammedaman Mama

Keyword(s):

Blood Group ◽

Malaria Infection ◽

Blood Donors ◽

Blood Groups ◽

High Rate ◽

Abo Blood Group ◽

Asymptomatic Malaria ◽

Abo Blood Groups ◽

Group Frequency ◽

Rh Blood Group

Background. Determination of the various ABO/Rh blood group distributions and their association with malaria infection has paramount importance in the context of transfusion medicine and malaria control. Methods. Facility based cross-sectional study was conducted from February to June, 2015, to assess ABO/Rh blood groups distribution and their association with asymptomatic malaria. A structured questionnaire was used to collect data. Blood grouping was done using monoclonal antibodies. Thin and thick blood films were examined for Plasmodium parasites. Data were analyzed using SPSS version 20.0. Results. A total of 416 blood donors participated with median age of 22±0.29 (median ± standard error of the mean). Distribution of ABO phenotypes, in decreasing order, was O (175, 42.1%), A (136, 32.7%), B (87, 20.9%), and AB (18, 4.3%). Most of them were Rh+ (386, 92.8%). The overall malaria prevalence was 4.1% (17/416). ABO blood group is significantly associated with malaria infection (P=0.022). High rate of parasitemia was seen in blood group O donors (6.899, P=0.003) compared to those with other ABO blood groups. Conclusion. Blood groups O and AB phenotypes are the most and the least ABO blood groups, respectively. There is significant association between ABO blood group and asymptomatic malaria parasitemia.

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Oral Contraceptive Types in Relation to ABO Blood Groups Among Saudi Women of Different Reproductive Age Groups and Impact on Venous Thromboembolism

Clinical and Applied Thrombosis/Hemostasis ◽

10.1177/1076029620966051 ◽

2020 ◽

Vol 26 ◽

pp. 107602962096605

Author(s):

Abdulrahman B. O. Mohamed ◽

Nabeel Al-Ama ◽

Huda Al Kreathy ◽

Khalid H. B. Ahmed ◽

Turki Al Amri ◽

...

Keyword(s):

Venous Thromboembolism ◽

Blood Group ◽

Protein C ◽

Second Generation ◽

Activated Protein C ◽

Blood Groups ◽

Fourth Generation ◽

Third Generation ◽

Abo Blood Groups ◽

Saudi Women

Saudi women have recently started using oral contraceptives (OCs), which has led to risk of venous thromboembolism (VTE). The risk varies with the type of OC generations used, and with OC use the risk for VTE increases by 2- to 6-fold. This study evaluated the effect of OC types in relation to ABO blood group on the risk of VTE among Saudi women. Thrombin generation (TG) was measured in the plasma of the women in the presence and absence of platelet rich plasma, platelet poor plasma and thrombomodulin or activated protein C. OC usage increased TG parameters ETP and Peak height by 9.81% and 16.04%, respectively. An increased risk of VTE was seen among women on third generation OCs as compared to those on second generation products. Within OC generations, we found that for women using fourth generation OCs, their ETP increased by 36.18% as compared to those using second generation and by 6.07% in those using third generation compared to those using second generation. There was significant difference with respect to ABO blood groups and OC generation types, but larger sample size is required. Women who are 40 years and older and using third generation OC had a higher risk of having thrombosis (11.84%), as compared to those using second generation OC (8.79%) and to those using fourth generation OC (5.03%). An association between different OC groups and non-O blood group in thrombosis generation was noted. TG parameters were significantly increased in relation to BMI when comparing to OC users versus non-users. In addition, inhibition of TG parameters in the presence of recombinant human thrombomodulin (TM) and activated protein C (APC) were significantly increased.

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Recovery of Blood Group Antibodies from Erythrocyte Powder

Blood ◽

10.1182/blood.v14.8.913.913 ◽

1959 ◽

Vol 14 (8) ◽

pp. 913-919

Author(s):

FELIX MILGROM ◽

CARLOS ORELLANA ◽

MIGUEL LAYRISSE

Keyword(s):

Blood Group ◽

Antibody Production ◽

Human Erythrocyte ◽

Blood Groups ◽

Natural Antibodies ◽

Red Cells ◽

Abo Blood Groups ◽

Negative Finding

Abstract A powder from dried human erythrocyte stromata was prepared to determine whether normal autoantibodies could be recovered from unsensitized erythrocyte powder and to study some of the properties of anti-A, anti-B and anti-Rho(D) antibodies recovered from sensitized powder. Twenty-five samples of unsensitized erythrocyte powder of all ABO blood groups were tested. The amount of eluted powder was as great as 200 mg., representing about 25 ml. of packed red cells. In no instance could antibody be detected in the eluates. This negative finding could be explained in three ways: by lack of antibody production, in disagreement with Landsteiner’s rule; by neutralization of antibody by a corresponding antigen before it reached the circulation; or by immediate elimination of sensitized erythrocytes from the circulation. The eluate of A erythrocyte powder sensitized with O serum agglutinated both A and B red cells. After neutralization with A polysaccharides, the anti-A antibody disappeared and anti-B remained. These experiments appear to support the theory of the multispecific character of natural antibodies. Rh-positive erythrocyte powder was sensitized with an incomplete anti-D (anti-Rho) serum and eluted in saline. The eluate did not agglutinate Rhpositive cells, but sensitized them for the action of Coombs’ serum. The mixture of Coombs’ serum with the eluate also produced agglutination of Rh-positive cells. These phenomena are explained as being due to the lack of or the very small amount of ballast proteins in the saline eluate.

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THE SIGNIFICANCE OF ABO COMPATIBILITY AND ITS RELATIONSHIP TO THE INTENSITY OF RH IMMUNIZATION

Blood ◽

10.1182/blood.v5.8.767.767 ◽

1950 ◽

Vol 5 (8) ◽

pp. 767-772 ◽

Cited By ~ 2

Author(s):

S. P. LUCIA ◽

MARJORIE L. HUNT

Keyword(s):

Blood Group ◽

Blood Groups ◽

Abo Blood Groups ◽

Hemolytic Disease ◽

Mother And Child ◽

Group A ◽

Obstetric Population ◽

Rh Immunization

Abstract 1. A series of 1337 obstetric cases, of which 170 were instances of sensitized Rh negative women, were studied with regard to (a) the incidence of the ABO blood groups, and (b) the incidence of ABO compatibility between the mother and child. 2. The incidence of ABO compatibility between the mother and child was found to vary with the blood group of the mother. 3. ABO compatibility between the mother and child was found to be present in 80 per cent of an unselected obstetric population in contrast to 95 per cent in a group of sensitized Rh negative women who bore infants afflicted with hemolytic disease of the newborn. 4. ABO compatibility appears to be related to the occurrence of hemolytic disease of the newborn. 5. In 120 sensitized Rh negative women who bore afflicted infants, the incidence of group A mothers was greater than expected.

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