Incidence of Chromosomal Abnormalities in Early-Stage River Buffalo Embryos Derived from in Vitro Fertilization

2010 ◽  
Vol 27 (3) ◽  
pp. 157-160 ◽  
Author(s):  
Midori Yoshizawa ◽  
Carlos Manuel Ulloa Ulloa ◽  
Danilda Hufana-Duran ◽  
Eufrocina Atabay ◽  
Peregrino G Duran ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Chromosomal Abnormalities ◽  
Early Stage ◽  
River Buffalo ◽  
Vitro Fertilization

Increased frequency of female partner chromosomal abnormalities in patients with high-order implantation failure after in vitro fertilization

2002 ◽  
Vol 78 (3) ◽  
pp. 515-519 ◽  
Author(s):  
Arieh Raziel ◽  
Shevach Friedler ◽  
Morey Schachter ◽  
Esti Kasterstein ◽  
Deborah Strassburger ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Chromosomal Abnormalities ◽  
High Order ◽  
Female Partner ◽  
Implantation Failure ◽  
Vitro Fertilization

scholarly journals Preimplantation genetic testing

2021 ◽  
Vol 2 (2) ◽  
pp. 52-63
Author(s):  
Ana Jeremić ◽  
Dragana Vuković ◽  
Srna Subanović ◽  
Jovana Broćić ◽  
Biljana Macanović
Keyword(s):  
Genetic Testing ◽  
In Vitro Fertilization ◽  
Success Rate ◽  
Embryo Transfer ◽  
Trinucleotide Repeat ◽  
Chromosomal Abnormalities ◽  
Preimplantation Genetic Testing ◽  
Vitro Fertilization

The application of preimplantation genetic testing (PGT) began in the late 1980s. Pre-implantation genetic testing, as the earliest possible method of prenatal diagnosis, enables the selection of embryos with a normal karyotype for embryo transfer. The use of preimplantation genetic testing has proven to be a useful method in the following three groups of inherited diseases: monogenic disorders (single gene defects), trinucleotide repeat disorders, and chromosomal abnormalities. The success rate of in vitro fertilization (IVF) has increased significantly since the introduction of PGT into clinical practice. This paper presents a literature review with the aim of clearly determining the role of PGT in embryo selection before embryo transfer, as well as the role of this type of testing in increasing the success rate of IVF. One of the goals of the paper is also to review the development of molecular genetic methods that are currently, or have once been, in routine use when performing PGT. The current literature is an indicator of the development and progress of molecular genetics techniques applied in PGT. At the same time, it provides an opportunity and an incentive for further extensive research that will lead to the improvement of preimplantation genetic testing and thus increase the success rate of in vitro fertilization.

CALM2 gene expression levels in the cumulus cells as a marker for chromosomal abnormalities in the embryo in in vitro fertilization programs

2016 ◽  
Vol 10_2016 ◽  
pp. 64-72
Author(s):  
Safronova N.A. Safronova ◽  
Kalinina E.A. Kalinina ◽  
Donnikov A.E. Donnikov ◽  
Burmenskaya O.V. Burmenskaya ◽  
Makarova N.P. Makarova ◽  
...  
Keyword(s):  
Gene Expression ◽  
In Vitro Fertilization ◽  
Chromosomal Abnormalities ◽  
Cumulus Cells ◽  
Vitro Fertilization ◽  
Expression Levels ◽  
Gene Expression Levels

Necessity is the mother of invention and the evolutionary force driving the success of in vitro fertilization

2020 ◽  
Author(s):  
Alison F Bartolucci ◽  
John J Peluso
Keyword(s):  
In Vitro Fertilization ◽  
Chromosomal Abnormalities ◽  
Healthy Children ◽  
Control Ovarian Stimulation ◽  
Stimulation Protocol ◽  
Vitro Fertilization ◽  
Evolutionary Force ◽  
Better Than ◽  
Human Ivf

Abstract During the last few decades, millions of healthy children have been born with the aid of in vitro fertilization (IVF). This success belies the fact that IVF treatment is comprised of a complex series of interventions starting with a customized control ovarian stimulation protocol. This is followed by the induction of oocyte maturation, the retrieval of mature oocytes and in vitro fertilization, which often involves the microinjection of a single sperm into the oocyte. After fertilization, the resulting embryos are cultured for up to 7 days. The best embryos are transferred into the uterus where the embryo implants and hopefully develops into a healthy child. However, frequently the best embryos are biopsied and frozen. The biopsied cells are analyzed to identify those embryos without chromosomal abnormalities. These embryos are eventually thawed and transferred with pregnancy rates as good if not better than embryos that are not biopsied and transferred in a fresh cycle. Thus, IVF treatment requires the coordinated efforts of physicians, nurses, molecular biologists and embryologists to conduct each of these multifaceted phases in a seamless and flawless manner. Even though complex, IVF treatment may seem routine today, but it was not always the case. In this review the evolution of human IVF is presented as a series of innovations that resolved a technical hurdle in one component of IVF while creating challenges that eventually lead to the next major advancement. This step-by-step evolution in the treatment of human infertility is recounted in this review.

scholarly journals The history of assisted reproductive technologies: from prohibition to recognition

2021 ◽  
Vol 11 (2) ◽  
pp. 315-328
Author(s):  
Maryna Petrushko ◽  
Volodymyr Piniaiev ◽  
Taisiia Yurchuk
Keyword(s):  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Chromosomal Abnormalities ◽  
Reproductive Potential ◽  
Married Couples ◽  
Reproductive Technologies ◽  
Infertility Treatment ◽  
Hereditary Diseases ◽  
Vitro Fertilization

The birth of children after infertility treatment of married couples with the help of assisted reproductive technologies has become a reality after many years of basic research on the physiology of reproductive system, development of oocyte’s in vitro fertilization methods and cultivation of embryos at pre-implantation stages. Given the widespread use of assisted reproductive technologies in modern medical practice and the great interest of society to this problem, the aim of the study was to trace the main stages and key events of assisted reproductive technologies in the world and in Ukraine, as well as to highlight the activities of outstanding scientists of domestic and world science who were at the origins of the development of this area. The paper used historical methods to study and interpret the texts of primary sources and present scientific historical events. In addition, the current trends in assisted reproductive technologies are covered based on the results of our own, more than 30 years of experience in the field of reproductive biology and medicine, and the achievements of world scientists. As a result of the work, it has been shown that despite certain ethical and social biases, the discovery of individual predecessor scientists became the basis for the efforts of Robert Edwards and Patrick Steptoe to ensure birth of the world's first child, whose conception occurred outside the mother's body. There are also historical facts and unique photos from our own archive, which confirm the fact of the first successful oocyte in vitro fertilization and the birth of a child after the use of assisted reproductive technologies in Ukraine. Over the last 20 years, assisted reproductive technologies have continued to grow, addressing many other issues of reproductive potential preservation and infertility treatment. State of the art methods of assisted reproductive technologies include the development of cryopreservation method of gametes and embryos by vitrification, genetic screening of embryos in order to prevent the hereditary diseases transmission and embryo transfer with chromosomal abnormalities, the birth of a child “from three parents” in severe cases of mutations in the mitochondrial genome, etc.

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