Serotyping and Antimicrobial Resistance Pattern of Streptococcus Pneumoniae Strains in Patients with Community-Acquired Pneumonia

2013 ◽  
Vol 22 (4) ◽  
pp. 69-80
Author(s):  
Mona Sallam Embarek Mohamed ◽  
Alaa Thabet Hassan
Keyword(s):  
Streptococcus Pneumoniae ◽  
Antimicrobial Resistance ◽  
Community Acquired Pneumonia ◽  
Resistance Pattern

scholarly journals Antimicrobial Resistance in Streptococcus pneumoniae: Implications for Patients With Community-Acquired Pneumonia

2000 ◽  
Vol 75 (11) ◽  
pp. 1161-1168 ◽  
Author(s):  
Carol E. Chenoweth ◽  
Sanjay Saint ◽  
Fernando Martinez ◽  
Joseph P. Lynch ◽  
A. Mark Fendrick
Keyword(s):  
Streptococcus Pneumoniae ◽  
Antimicrobial Resistance ◽  
Community Acquired Pneumonia

Bacterial aetiology and antimicrobial resistance of community-acquired pneumonia in the elderly and younger adults

2010 ◽  
Vol 40 (2) ◽  
pp. 89-91 ◽  
Author(s):  
Seyyed Hamid Hashemi ◽  
Golnoosh Soozanchi ◽  
Shirin Jamal-Omidi ◽  
Rasoul Yousefi-Mashouf ◽  
Mojgan Mamani ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
General Trend ◽  
The Elderly ◽  
Community Acquired Pneumonia ◽  
Resistance Pattern ◽  
Age Group ◽  
Younger Adults ◽  
Streptococcus Pneumonia ◽  
Bacterial Aetiology ◽  
And Staphylococcus Aureus

This study was undertaken in order to compare the frequency of bacterial agents of community-acquired pneumonia (CAP) and their antimicrobial resistance in the elderly and younger adults admitted to a teaching hospital in Hamedan, Iran. A total of 150 cases of CAP, including 81 elderly and 69 younger adults, were evaluated. The most frequently identified pathogens in younger adults were Moraxella catarralis (11.5%), Streptococcus pneumonia (10.1%) and Staphylococcus aureus (10.1%); while in the elderly the most frequent were S. pneumonia (12.3%), S. aureus (6.1%) and Pseudomonas aeruginosa (6.1%). No significant differences were observed between the frequency and antimicrobial resistance pattern of isolated pathogens in either age group. We concluded that the cause of CAP in the elderly follows the general trend of infection in the younger population. Increased resistance of isolated bacteria to the current antibiotics highlights the need for further investigation of newer antibiotics for the treatment of CAP.

Community acquired pneumonia-current scenario among immunocompromised patients in a tertiary care hospital

2016 ◽  
Vol 5 (01) ◽  
pp. 4715
Author(s):  
A. V. Sowmya* ◽  
G. Jayalakshmi ◽  
David Agatha
Keyword(s):  
Diabetes Mellitus ◽  
Antimicrobial Therapy ◽  
Tertiary Care ◽  
Community Acquired Pneumonia ◽  
Polymicrobial Infection ◽  
Resistance Pattern ◽  
Care Hospital ◽  
Immunocompromised Patients ◽  
Drug Resistant ◽  
Etiologic Agents

Pneumonia is a common illness accounting for majority of hospitalizations worldwide with significant mortality and morbidity. Antimicrobial therapy, being the main stay of treatment, the choices of antibiotics depends on the nature of the etiologic agents and the host factors. The current study was aimed to identify the bacterial & fungal etiologic agents of Community Acquired Pneumonia (CAP) in Immunocompromised (IC) patients, with their antimicrobial resistant pattern and to analyze the associated immunocompromised states. Various respiratory samples from study group of 75 immunocompromised patients with features of pneumonia were collected, processed and the isolates were identified with their antimicrobial susceptibility& resistance pattern according to CLSI guidelines. The results were analyzed statistically. Diabetes mellitus is the most common immunocompromised state (48%) associated with CAP. Monomicrobial and polymicrobial infection rates were 80.36% and 19.64% respectively. Gram negative pathogens and fungal pathogens were identified in 60% and 25.37% of culture positive cases respectively. Diabetes mellitus is commonly found in association with polymicrobial infection (19.44%) and fungal infection (16.66%). Drug resistant strains comprise about 75% of MRSA strains, 72.72 % of ESBL producers and 3.44% of Amp C producers. As the number of elderly people with associated IC state is on rise, with change in the pattern of microbial etiologic agents causing CAP, a prior knowledge of the host and microbial factors will help in formulating empirical antimicrobial therapy and proper treatment thereby curbing the spread of infections by drug resistant pathogens and the associated morbidity and mortality.

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