METAL-RICH PARTICULATE MATTER INFLUENCE EPSTEIN-BARR VIRUS METHYLATION IN PERIPHERAL BLOOD LEUKOCYTES.

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Valentina Bollati ◽  
Laura Angelici ◽  
Matteo Bonzini ◽  
Letizia Tarantini ◽  
Pietro Apostoli ◽  
...  
PEDIATRICS ◽  
1979 ◽  
Vol 64 (6) ◽  
pp. 945-945
Author(s):  
Crystie C. Halsted ◽  
R. Shihman Chang

In the article "Infectious Mononucleosis and Encephalitis: Recovery of EB Virus from Spinal Fluid" by Halsted and Chang (Pediatrics 64:257-258, 1979), reference 9 should be added as follows: Rocchi F, de Felici A, Ragona G, et al: Quantitative evaluation of Epstein-Barr-virus-infected mononuclear peripheral blood leukocytes in infectious mononucleosis. N Engl J Med 296:132, 1977. On page 258, first column, 12 lines from bottom, reference 5 should read reference 9.


1995 ◽  
Vol 60 (6) ◽  
pp. 547-553 ◽  
Author(s):  
DAVID N. KENAGY ◽  
YECHIEL SCHLESINGER ◽  
KAREN WECK ◽  
JON H. RITTER ◽  
M. MONIQUE GAUDREAULT-KEENER ◽  
...  

2018 ◽  
Vol 20 (6) ◽  
pp. 865-870
Author(s):  
L. M. Kurtasova ◽  
N. A. Shakina ◽  
A. R. Smidt ◽  
L. A. Ikkes

Our aim was to study the effect of cycloferon on in vitro susceptibility of peripheral blood leukocytes to interferon-α2 in children with infectious mononucleosis in acute phase caused by Epstein-Barr virus (EBV). Materials and methods were as follows: the study included 23 children 4 to 6 years of age admitted in acute period of infectious mononucleosis. The control group consisted of 15 healthy children of the same age group. In vitro susceptibility of peripheral blood leukocytes to interferon-α2 was determined by the method of L.M. Kurtasova (2007).Four types of in vitro response of peripheral blood leukocytes to interferon-α2 upon induction by cycloferon have been revealed in both healthy children and patients with EBV-positive infectious mononucleosis. Differences in occurrence rates of these 4 types of reactions have been found among patients with EBVinfection, in comparison with the group of healthy children. There was no regular dose-dependent changes in susceptibility of peripheral blood  leukocytes to interferon-α2 in vitro after cycloferon induction in the group of children with EBV-infection. depending on the dose, which have been revealed in healthy children.


Author(s):  
C. M. Payne ◽  
P. M. Tennican

In the normal peripheral circulation there exists a sub-population of lymphocytes which is ultrastructurally distinct. This lymphocyte is identified under the electron microscope by the presence of cytoplasmic microtubular-like inclusions called parallel tubular arrays (PTA) (Figure 1), and contains Fc-receptors for cytophilic antibody. In this study, lymphocytes containing PTA (PTA-lymphocytes) were quantitated from serial peripheral blood specimens obtained from two patients with Epstein -Barr Virus mononucleosis and two patients with cytomegalovirus mononucleosis. This data was then correlated with the clinical state of the patient.It was determined that both the percentage and absolute number of PTA- lymphocytes was highest during the acute phase of the illness. In follow-up specimens, three of the four patients' absolute lymphocyte count fell to within normal limits before the absolute PTA-lymphocyte count.In one patient who was followed for almost a year, the absolute PTA- lymphocyte count was consistently elevated (Figure 2). The estimation of absolute PTA-lymphocyte counts was determined to be valid after a morphometric analysis of the cellular areas occupied by PTA during the acute and convalescent phases of the disease revealed no statistical differences.


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