scholarly journals Exposure to environmental contaminants and risk of pregnancy induced hypertension and gestational diabetes mellitus

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
R. Khalili ◽  
V. Vieira
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Environmental Contaminants ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension

Causation between Gestational Diabetes Mellitus(GDM) and Pregnancy Induced Hypertension(PIH): A Statistic Case Study in Harbin, China

2021 ◽  
Author(s):  
Dan DIAO ◽  
DIAO Fang ◽  
XIAO Bin ◽  
Ning LIU ◽  
Fengjuan LI ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Causal Effect ◽  
Pregnancy Induced Hypertension ◽  
Essential Information ◽  
Induced Hypertension ◽  
Inference Theory ◽  
Statistical Results

Abstract Both gestational diabetes mellitus(GDM) and pregnancy induced hypertension (PIH) would influence the gestation significantly. However, the causation between these two symptoms remains speculative. 16,404 pregnant women were identified in Harbin, China in this study. We investigated the evaluate the causal effect of GMD on PIH based on the statistic inference theory. The statistical results indicated that GDM might cause PIH. Also, this case study demonstrated that the decrease temperature might also cause hypertension during pregnancy, and the prevalence rate of GDM increased with age. However, the prevalence of diabetes did not show a remarkable difference in varied areas and ages. This study could provide some essential information that will help to investigate the mechanism for GDM and PIH.

scholarly journals Risks for Gestational Diabetes Mellitus and Pregnancy-Induced Hypertension Are Increased in Polycystic Ovary Syndrome

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Yunhui Wang ◽  
Xiaomiao Zhao ◽  
Huidan Zhao ◽  
Hong Ding ◽  
Jianping Tan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Polycystic Ovary Syndrome ◽  
Gestational Diabetes Mellitus ◽  
Ovarian Stimulation ◽  
Polycystic Ovary ◽  
Pregnancy Induced Hypertension ◽  
Ovary Syndrome ◽  
Induced Hypertension ◽  
Ivf Et

Objectives. To evaluate pregnancy outcomes and its determinants in women with polycystic ovary syndrome (PCOS).Methods. Two-hundred and twenty pregnant PCOS and 594 healthy women were followed from early pregnancy. Incidences of gestational diabetes mellitus (GDM), pregnancy-induced hypertension (PIH), preterm birth, twinning, and fetal growth restriction (FGR) were determined.Results. The incidence of GDM was notably higher among all PCOS combined (54.9%; OR: 2.9, 95% CI: 2.0–4.1) and PCOS subgroups, whether they conceived spontaneously (51.5%; OR: 3.3, 95% CI: 2.0–5.4), or via IVF-ET or ovarian stimulation, compared with controls (14.3%;P<0.001). The incidence of PIH was also higher among all PCOS (10.4%; OR: 2.2, 95% CI: 1.1–4.4) and the subgroup conceiving spontaneously (11.8%; OR: 2.6, 95% CI: 1.1–6.2;P<0.001) but not for those conceiving with IVF-ET (9.1%) or ovarian stimulation (9.4%). Lean women with PCOS (BMI<24kg/m2) had higher incidences of GDM (51.1% versus 14.5%; OR: 5.6, 95% CI: 3.4–9.0) and PIH (8.9% versus 3.2%; OR: 3.0, 95% CI: 1.3–7.1) than lean controls. PCOS woemn with normal glucose tolerance had higher risk for PIH than their comparable control group (OR: 4.0, 95% CI: 1.3–11.7).Conclusion. This study suggested that PCOS is an independent risk factor for the development of GDM and PIH. This trial is registered withChiCTR-RCC-11001824.

scholarly journals The Risk for Future Cerebrovascular Disease in Pregnant Women With Moyamoya Disease: A Nationwide Population-Based Study in South Korea

2021 ◽  
Author(s):  
Yeonseong Jeong ◽  
Yun Ji Jung ◽  
Eunjin Noh ◽  
Geum Joon Cho ◽  
Min-Jeong Oh ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Health Insurance ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Cerebrovascular Disease ◽  
Moyamoya Disease ◽  
Chronic Hypertension ◽  
Pregnancy Induced Hypertension ◽  
Increased Risk ◽  
Induced Hypertension

Abstract Background: Physiologic changes during pregnancy affect the development of postpartum cerebrovascular disease (CVD) in women with Moyamoya disease (MMD). Due to the rare prevalence of MMD and large regional variations, large-scale studies on the risk of CVD after delivery have not been conducted. The aim of this study was to evaluate whether women with MMD have an increased risk of CVD after delivery.Methods: Research data was collected from the National Health Insurance Claims Database of the Health Insurance Review and Assessment Service. Patients delivered in Korea from 2007 to 2014 were enrolled. We classified women as CVD if they were diagnosed with stroke and/or cerebral infarction and/or intracranial hemorrhage and/or subarachnoid hemorrhage between delivery and December 31, 2016. To evaluate adjusted hazard ratio for CVD in women with MMD, we used multivariate Cox proportional hazard regression.Results: Among 3,611,216 Korean women who had delivery, 382 had Moyamoya disease. When compared to women without MMD, women with MMD had a higher prevalence of pregestational diabetes and chronic hypertension. Also, women with MMD had a significantly higher incidence of cesarean section, pregnancy-induced hypertension, and gestational diabetes mellitus (p<0.0001, <0.0001, 0.02, respectively). Among women with MMD, a total of 246(64.4%) women developed CVD within the follow-up postpartum period, and 87.8% occurred within 2 years of postpartum. Women with MMD were associated with an increased risk of CVD in later (adjusted HR 108.24; 95% CI, 95.37-122.86) after adjusting for maternal age, parity, pregnancy-induced hypertension, gestational diabetes mellitus, pregestational diabetes, chronic hypertension.Conclusion: Our study showed that the incidence of CVD after delivery was higher in women with MMD. Therefore, we have to have more cautions of women with MMD and provide long-term postpartum surveillance

A COMPARATIVE STUDY OF MACROSCOPIC MORPHOLOGY OF PLACENTA AMONG NORMAL AND COMPLICATED PREGNANCIES

2021 ◽  
pp. 36-39
Author(s):  
Soumya Soumya ◽  
Kumari Bibha ◽  
Birendra Kumar Sinha ◽  
Debarshi Jana
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Multiple Pregnancy ◽  
Valuable Insight ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension ◽  
Uterine Growth ◽  
Intra Uterine Growth Retardation

The placenta being a foetal organ, undergoes the same stress and strain to which the foetus is exposed. Common yet life threatening complications of Pregnancy like Gestational Diabetes, Hypertension, Anaemia and Intra uterine growth retardation result in both macroscopic as well as microscopic changes in the placenta. Hence study of the placenta will give a valuable insight in cases of adverse foetal outcome. The present study was conducted on a total of two hundred and ninety two freshly delivered placentae with umbilical cord obtained from the labour rooms and operation theatres of the Department of Obstetrics & Gynaecology and received at the Department Of Anatomy, PMCH, Patna, Bihar. Exclusion criteria was multiple pregnancy. Inclusion criteria's were normal uncomplicated primigravida and multigravida and pathological factors complicating pregnancy like Anaemia, Gestational Diabetes mellitus, Pregnancy induced Hypertension and prematurity. The 292 placentae were divided into four categories according to the risk factors and clinical diagnosis of pregnant women namely normal patients (147), patients with Pregnancy induced hypertension (15), Gestational Diabetes mellitus (30), anaemia (65) and preterm (35). The circular type of placenta is the common shape of placenta. The diameter of the placenta is increased in anaemia, gestational diabetes and decreased in prematurity. The weight of the placenta is increased in gestational diabetes mellitus, anaemia and decreased in prematurity. The number of maternal cotyledons is decreased in prematurity and increased in gestational diabetes mellitus. The eccentric type of cord attachment is the most common type in complicated pregnancies. The diagnosis of such risk factors in pregnancies during antenatal period and early intervention will improve the perinatal outcome.

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