Deep dissecting haematoma in patients with dermatoporosis: implications for home nursing

2021 ◽  
Vol 26 (Sup3) ◽  
pp. S6-S13
Author(s):  
Valentina Vanzi ◽  
Elena Toma
Keyword(s):  
Wound Healing ◽  
Emergency Management ◽  
Lower Limb ◽  
Essential Role ◽  
Early Recognition ◽  
Wound Management ◽  
Home Nursing ◽  
High Prevalence ◽  
Clinical Emergency

Dermatoporosis is a chronic cutaneous insufficiency/fragility syndrome with a high prevalence in older adults. Dermatoporotic skin becomes thin and fragile and tends to tear. It may lead to deep dissecting haematomas (DDHs) as a final stage of dermatoporosis, which is a clinical emergency. Management can be challenging, as patients with lower-limb haematomas are frequently older and affected by multiple comorbidities, or are probably on medications that negatively influence wound healing. This article describes the essential role of nurses in prevention, early recognition and wound management of DDHs in patients with dermatoporosis.

The significance of collagen dressings in wound management: a review

2018 ◽  
Vol 27 (10) ◽  
pp. 692-702 ◽  
Author(s):  
Frank Pallaske ◽  
Anett Pallaske ◽  
Kurt Herklotz ◽  
Joachim Boese-Landgraf
Keyword(s):  
Wound Healing ◽  
Health Professionals ◽  
Clinical Studies ◽  
Critical Appraisal ◽  
Wound Dressings ◽  
Wound Management ◽  
Complex Field ◽  
The Right ◽  
New Applications

Clinical experience and research has improved our understanding of wound healing which, in turn, has enabled health professionals to aid wound healing and manufacturers to develop modern wound dressings. The significant role of collagen in wound healing has led to the development of numerous products on the basis of this biological material. The main focus of this review is to provide a critical appraisal of publications about collagen and acellular collagen dressings with a fleece-like or spongy structure. It is intended for clinicians and researchers, and aims to keep them up-to-date in the complex field of interactive, collagen-based wound dressings, including their manufacture, combination possibilities, mechanisms of action, performance in the promotion of wound healing and indications. Despite the small number of clinical studies, the importance of acellular collagen dressings with a fleece- or sponge-like structure is likely to increase in the future. As there is no ideal wound dressing, the knowledge attained is meant to support health professionals in selecting the right product, and pave the way for new applications and clinical studies.

scholarly journals An Essential Role of NRF2 in Diabetic Wound Healing

Diabetes ◽  
2015 ◽  
Vol 65 (3) ◽  
pp. 780-793 ◽  
Author(s):  
Min Long ◽  
Montserrat Rojo de la Vega ◽  
Qing Wen ◽  
Manish Bharara ◽  
Tao Jiang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Essential Role ◽  
Diabetic Wound ◽  
Diabetic Wound Healing

scholarly journals The role of the dentist and orthodontist in recognizing oro-facial manifestations of acromegaly: a questionnaire-based study

Pituitary ◽  
2021 ◽  
Author(s):  
Giorgia Preo ◽  
Alberto De Stefani ◽  
Francesca Dassie ◽  
Alexandra Wennberg ◽  
Roberto Vettor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Early Recognition ◽  
Sella Turcica ◽  
Mandibular Prognathism ◽  
Oral Manifestation ◽  
Number Of Patients ◽  
High Prevalence ◽  
Strategic Role

Abstract Purpose Oro-facial manifestations of acromegaly are among the earliest signs of the disease and are reported by a significant number of patients at diagnosis. Despite this high prevalence of acromegaly oral manifestation, dentists do not play a pivotal role in acromegaly identification and diagnosis. The aim of our study was to evaluate the ability of dentists and orthodontists in the early recognition of the oro-facial manifestations of acromegaly. Methods A telematic questionnaire was administered to dentists and orthodontists. The questionnaire included photos with facial and oral-dental details and lateral teleradiography of acromegaly patients (ACRO). Results The study included 426 participants: 220 dentists and 206 orthodontists. Upon reviewing the photos, dentists most often observed mandibular prognathism and lips projection, while orthodontists also reported the impairment of relative soft tissue. Orthodontists, who usually use photos to document patients’ oral-facial characteristics, paid more attention to oral-facial impairment than dentists. During dental assessment, 90% of the participants usually evaluated tongue size and appearance, diastemas presence, and signs of sleep impairment (mainly orthodontists). Orthodontists were also more able to identify sella turcica enlargement at teleradiography. A total of 10.8% of the participants had ACRO as patients and 11.3% referred at least one patient for acromegaly suspicion. Conclusion The study highlighted dentists’ strategic role in identifying ACRO. Increasing dentists’ awareness about acromegaly clinical issues may improve early diagnosis, potentially resulting in an increased quality of life and decreased mortality among ACRO.

Revisiting the essential role of oxygen in wound healing

2003 ◽  
Vol 186 (3) ◽  
pp. 259-263 ◽  
Author(s):  
Gayle M Gordillo ◽  
Chandan K Sen
Keyword(s):  
Wound Healing ◽  
Essential Role

scholarly journals Role of early debridement in non-healing ulcer

2017 ◽  
Vol 4 (12) ◽  
pp. 3976
Author(s):  
Darshan Tote ◽  
Suhas Jajoo ◽  
Sachin Tote
Keyword(s):  
Wound Healing ◽  
Financial Burden ◽  
Complete Healing ◽  
Wound Management ◽  
Financial Loss ◽  
Healing Ulcer ◽  
Early Recovery ◽  
Healing Wound ◽  
Early Debridement

Background: Non-healing wound is a commonly encountered entity with a broader effect on both the sufferer and the treating doctor. Time taken in healing these wound is directly related to financial loss as well as loss of working hours, thus ultimately increasing the financial burden. Chronic wound has devitalized tissue at the base which is barrier to cell migration and acts as supportive environment for bacterial growth. Considering the effect of devitalized tissue on wound healing there lies importance of debridement in wound management. Debridement is an effective technique to achieve desirable wound bed preparation by removing the dead and devitalized tissue. Hence a study was conducted at a rural hospital with main aim to assess role of surgical sharp debridement in non-healing wound in complete healing or preparing wound for further definitive treatment.Methods: The study was conducted at AVBRH Sawangi (Meghe), Wardha. Random 50 patients of non-healing ulcer were selected for the study. One group was of early debridement while other group of dressing with moist dressing only. Wound were assessed for healing, wound contraction, scar quality at regular intervals. They were assessed for duration of wound to heal completely/ get ready for further intervention like SSG/ Flaps, Cost of treatment and Time taken by the patient to return back to work.Results: 36% of patients in moist dressing group heal completely by 4 weeks while 56% of patients in debridement group heal completely by 4 weeks. Early recovery leads to early normalcy so less loss of wages and thus making the group cost effective.Conclusions: Early debridement was found to be an effective tool in wound healing in non-healing ulcers.

The Role of Matrix Metalloproteinases in Wound Healing

2002 ◽  
Vol 92 (1) ◽  
pp. 12-18 ◽  
Author(s):  
David G. Armstrong ◽  
Edward B. Jude
Keyword(s):  
Wound Healing ◽  
Matrix Metalloproteinases ◽  
Matrix Metalloproteinase ◽  
Chronic Wounds ◽  
Basic Knowledge ◽  
Collagenolytic Activity ◽  
Tissue Inhibitors Of Metalloproteinase ◽  
High Prevalence ◽  
Healing Wounds

The structure, classification, function, and regulation of matrix metalloproteinases in normal and abnormal wound healing is discussed. Results from key studies suggest that neutrophil-derived matrix metalloproteinase 8 (MMP-8) is the predominant collagenase present in normal healing wounds, and that overexpression and activation of this collagenase may be involved in the pathogenesis of nonhealing chronic leg ulcers. Excessive collagenolytic activity in these chronic wounds is possible because of the reduced levels of tissue inhibitor metalloproteinase 1 (TIMP-1). However, until recently, there have been no studies evaluating levels of matrix metalloproteinase or tissue inhibitors of metalloproteinase activity in chronic diabetic foot wounds. Improving basic knowledge and pharmaceutical intervention in this area ultimately may help clinicians identify and proactively intervene in an effort to prevent normal wounds from becoming chronic. This may prevent the high prevalence of morbidity associated with this significant health problem. (J Am Podiatr Med Assoc 92(1): 12-18, 2002)

scholarly journals Peripheral (not central) corneal epithelia contribute to the closure of an annular debridement injury

2019 ◽  
Vol 116 (52) ◽  
pp. 26633-26643 ◽  
Author(s):  
Mijeong Park ◽  
Alexander Richardson ◽  
Elvis Pandzic ◽  
Erwin P. Lobo ◽  
J. Guy Lyons ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Essential Role ◽  
Wound Closure ◽  
Cell Behavior ◽  
Epithelial Stem Cells ◽  
Self Renewal ◽  
Central Cornea ◽  
Limbal Epithelial Stem Cells

Corneal epithelia have limited self-renewal and therefore reparative capacity. They are continuously replaced by transient amplifying cells which spawn from stem cells and migrate from the periphery. Because this view has recently been challenged, our goal was to resolve the conflict by giving mice annular injuries in different locations within the corneolimbal epithelium, then spatiotemporally fate-mapping cell behavior during healing. Under these conditions, elevated proliferation was observed in the periphery but not the center, and wounds predominantly resolved by centripetally migrating limbal epithelia. After wound closure, the central corneal epithelium was completely replaced by K14+limbal-derived clones, an observation supported by high-resolution fluorescence imaging of genetically marked cells in organ-cultured corneas and via computational modeling. These results solidify the essential role of K14+limbal epithelial stem cells for wound healing and refute the notion that stem cells exist within the central cornea and that their progeny have the capacity to migrate centrifugally.

Honey: An Effective Regenerative Medicine Product in Wound Management

2019 ◽  
Vol 26 (27) ◽  
pp. 5230-5240 ◽  
Author(s):  
Simona Martinotti ◽  
Marcela Bucekova ◽  
Juraj Majtan ◽  
Elia Ranzato
Keyword(s):  
Wound Healing ◽  
Regenerative Medicine ◽  
Tissue Regeneration ◽  
Potential Role ◽  
Wound Management ◽  
Physiological Basis ◽  
Speed Up ◽  
Healing Wounds ◽  
Medicine Product

:Honey has successfully been used in the treatment of a broad spectrum of injuries including burns and non-healing wounds. It acts as an antibacterial and anti-biofilm agent with anti/pro-inflammatory properties. However, besides these traditional properties, recent evidence suggests that honey is also an immunomodulator in wound healing and contains several bee and plant-derived components that may speed up wound healing and tissue regeneration process. Identifying their exact mechanism of action allows better understanding of honey healing properties and promotes its wider translation into clinical practice.:This review will discuss the physiological basis for the use of honey in wound management, its current clinical uses, as well as the potential role of honey bioactive compounds in dermal regenerative medicine and tissue re-modeling.

Role of oxygen in wound healing

2020 ◽  
Vol 29 (Sup5b) ◽  
pp. S4-S10 ◽  
Author(s):  
Ibby Younis
Keyword(s):  
Wound Healing ◽  
Host Resistance ◽  
Essential Role ◽  
Oxygen Supply ◽  
Healing Process ◽  
Wound Healing Process ◽  
Tissue Formation ◽  
Granulation Tissue Formation ◽  
Resistance To Infection

Not only does oxygen play an essential role in each stage of the wound healing process. It also helps to increases host resistance to infection. Any impairment to the oxygen supply can therefore delay healing. This article explores the affects of oxygen on the wound cells and tissue, and explains how an adequate supply is required for granulation tissue formation and epithelialisation to occur

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