scholarly journals Role of early debridement in non-healing ulcer

2017 ◽  
Vol 4 (12) ◽  
pp. 3976
Author(s):  
Darshan Tote ◽  
Suhas Jajoo ◽  
Sachin Tote

Background: Non-healing wound is a commonly encountered entity with a broader effect on both the sufferer and the treating doctor. Time taken in healing these wound is directly related to financial loss as well as loss of working hours, thus ultimately increasing the financial burden. Chronic wound has devitalized tissue at the base which is barrier to cell migration and acts as supportive environment for bacterial growth. Considering the effect of devitalized tissue on wound healing there lies importance of debridement in wound management. Debridement is an effective technique to achieve desirable wound bed preparation by removing the dead and devitalized tissue. Hence a study was conducted at a rural hospital with main aim to assess role of surgical sharp debridement in non-healing wound in complete healing or preparing wound for further definitive treatment.Methods: The study was conducted at AVBRH Sawangi (Meghe), Wardha. Random 50 patients of non-healing ulcer were selected for the study. One group was of early debridement while other group of dressing with moist dressing only. Wound were assessed for healing, wound contraction, scar quality at regular intervals. They were assessed for duration of wound to heal completely/ get ready for further intervention like SSG/ Flaps, Cost of treatment and Time taken by the patient to return back to work.Results: 36% of patients in moist dressing group heal completely by 4 weeks while 56% of patients in debridement group heal completely by 4 weeks. Early recovery leads to early normalcy so less loss of wages and thus making the group cost effective.Conclusions: Early debridement was found to be an effective tool in wound healing in non-healing ulcers.

2021 ◽  
Vol 26 (Sup3) ◽  
pp. S6-S13
Author(s):  
Valentina Vanzi ◽  
Elena Toma

Dermatoporosis is a chronic cutaneous insufficiency/fragility syndrome with a high prevalence in older adults. Dermatoporotic skin becomes thin and fragile and tends to tear. It may lead to deep dissecting haematomas (DDHs) as a final stage of dermatoporosis, which is a clinical emergency. Management can be challenging, as patients with lower-limb haematomas are frequently older and affected by multiple comorbidities, or are probably on medications that negatively influence wound healing. This article describes the essential role of nurses in prevention, early recognition and wound management of DDHs in patients with dermatoporosis.


2018 ◽  
Vol 27 (10) ◽  
pp. 692-702 ◽  
Author(s):  
Frank Pallaske ◽  
Anett Pallaske ◽  
Kurt Herklotz ◽  
Joachim Boese-Landgraf

Clinical experience and research has improved our understanding of wound healing which, in turn, has enabled health professionals to aid wound healing and manufacturers to develop modern wound dressings. The significant role of collagen in wound healing has led to the development of numerous products on the basis of this biological material. The main focus of this review is to provide a critical appraisal of publications about collagen and acellular collagen dressings with a fleece-like or spongy structure. It is intended for clinicians and researchers, and aims to keep them up-to-date in the complex field of interactive, collagen-based wound dressings, including their manufacture, combination possibilities, mechanisms of action, performance in the promotion of wound healing and indications. Despite the small number of clinical studies, the importance of acellular collagen dressings with a fleece- or sponge-like structure is likely to increase in the future. As there is no ideal wound dressing, the knowledge attained is meant to support health professionals in selecting the right product, and pave the way for new applications and clinical studies.


2021 ◽  
Vol 12 (1) ◽  
pp. 133-136
Author(s):  
Madhuri Vitthalrao Bhandare ◽  
Sagar Raghunath Mhatre ◽  
Pooja Vitthalrao Bhandare

Wound and its management is one of the most important basic principle of surgery. In modern surgery text wound is described in detail but first evidences are available in ancient Indian system of medicine namely Ayurveda as Vrana and Vrana Ropana (wound healing). Most of the acharyas described it in Samhitas but Sushruta described it in a complete manner which is also practically implemented in various types of wound and specially very useful in non-healing wound where modern surgery has some limitations. Hence in this review article wound management by Sushruta is focused and collected in one article which is scattered in various Adhyaya of Sushruta Samhita.


2020 ◽  
Vol 27 (06) ◽  
pp. 1249-1254
Author(s):  
Ibrahim Yamin ◽  
Ayesha ◽  
Ramla ◽  
Muhammad Ajmal

Objectives: The use of human amniotic membrane is essential new concept in wound healing which functions as a biodegradable scaffold on wound surface, as it is a rich hub of stem cells which play an important role in wound healing. Study Design: Randomized Control Trial. Setting: Department of Surgery THQ Hospital Gojra. Period: 1st January 2019 to 30 September 2019. Material & Methods: Experimental study using clinical trial. A case series of 50 patient cases were picked from surgical OPD. Who fall in criteria of chronic non-healing wound with at least three months duration comprising of diabetic, venous ulcers and traumatic non healing wound and neuropathic ulcers. All located on lower limbs. Results: All 50 patient were treated with standard protocol by applying freshly prepared amniotic membrane out of which 4 chronic wounds more than 4 year duration were not healed and 2 cases escaped from the study. HAM dressing was changed after every 7 days and its effect were studied by seeing measuring the reduction in wound size and improvement in pain, swelling and mental stress. Success rate was found about 90% with complete healing. Conclusion: There is a dire need in developing countries to promote the use of HAM, in chronic non healing wounds which is a biological membrane, readily available (free if fresh) with simple sterilization techniques, easy storage and easy application with ultimate goal in achieving speedy cost effective wound healing.


2004 ◽  
Vol 92 (08) ◽  
pp. 275-280 ◽  
Author(s):  
Julia Dovi ◽  
Anna Szpaderska ◽  
Luisa DiPietro

SummaryCells of the innate immune system, including neutrophils and macrophages, are a highly visible component of normal wound healing in adult mammals. The role of inflammatory cells in the healing wound has been widely investigated, and evidence for both positive and negative influences exists. Several recent investigations support the emerging paradigm that robust inflammation is detrimental to wound closure. This developing information suggests that the functional role of inflammatory cells in wound healing must be reevaluated.


Author(s):  
Balap A.R ◽  
Gaikwad A.A

A large portion of the world's population relies on herbs for medical purposes today. About 25-30% of modern drugs are chemical intermediates derived from plant constituents. Traditional medicinal plant preparations are frequently utilised for wound healing, encompassing a wide range of skin-related disorders. In wound management, herbal medicine entails cleaning, debridement, and the creation of an environment that promotes natural healing. This review discusses wound, healing of the wound, allopathic treatment in wound healing, types of herbal medicines used in the treatment of wound healing and common excipients used in topical herbal formulations. In this article, we look at 15 plants that have been utilised as wound healers in traditional medicine around the world. This study is an attempt to search the difficulties and challenges of herbal formulations need for novel drug delivery system nanocarriers for herbal remedies with other nanotechnology strategies and techniques as a new drug delivery system and its future prospective. The purpose of this review is to examine the most common excipients used in herbal formulations, as well as various medicinal plants traditionally used in wound healing, wound healing difficulties and challenges, the use of nanotechnology in herbal formulation, the future scope of herbal medicines in wound healing, and a comparison of allopathy and herbal formulations.


2013 ◽  
Vol 2 (1) ◽  
pp. 2
Author(s):  
Muhammad Usman Khan

Burn wounds are categorized among the most severe injuries an individual can experience1. These are one of the major health problems worldwide. Even in case of small burn it causes high economic burden on the family and the society. In burns, early recovery is considered as an integral part of the treatment, which is not in terms of healing wound only, but it is an overall process retrieval including physical activities, decreasing psychological problems and focus on cosmetic issue. It is evident that treatment must begin immediately after the injury and last up to months or even years2. Lack of emphasis on physical rehabilitation of burns patient is a source of concern and here I would like to draw your attention to the problems in case proper rehabilitation does not commence.


2019 ◽  
Vol 26 (27) ◽  
pp. 5230-5240 ◽  
Author(s):  
Simona Martinotti ◽  
Marcela Bucekova ◽  
Juraj Majtan ◽  
Elia Ranzato

:Honey has successfully been used in the treatment of a broad spectrum of injuries including burns and non-healing wounds. It acts as an antibacterial and anti-biofilm agent with anti/pro-inflammatory properties. However, besides these traditional properties, recent evidence suggests that honey is also an immunomodulator in wound healing and contains several bee and plant-derived components that may speed up wound healing and tissue regeneration process. Identifying their exact mechanism of action allows better understanding of honey healing properties and promotes its wider translation into clinical practice.:This review will discuss the physiological basis for the use of honey in wound management, its current clinical uses, as well as the potential role of honey bioactive compounds in dermal regenerative medicine and tissue re-modeling.


2021 ◽  
Vol 23 (9) ◽  
pp. 823-833
Author(s):  
Mirja C Nolff

Practical relevance: Open wounds and their treatment present a common challenge in veterinary practice. Approaching 15 years ago negative pressure wound therapy (NPWT) started to be incorporated into clinical veterinary medicine, and its availability is becoming more widespread in Europe and the USA. Use of this therapy has the potential to significantly increase the healing rate of open wounds as well as free skin grafts in small animals, and it has been occasionally described for the management of feline wounds. Aim: This review describes the mechanisms of action of, and indications for, NPWT, and offers recommendations for NPWT specific to feline patients. Evidence base: The information presented is based on the current evidence and the author’s clinical experience of the technique gained over the past 12 years. Comparative studies of different treatment options are lacking and, since wound healing in cats and dogs differs, cat-specific studies are especially needed. Well-designed wound healing studies comparing different advanced techniques will improve open wound healing in cats in the future, and potentially allow better understanding of the role of NPWT in this setting.


1997 ◽  
Vol 1 (1) ◽  
pp. 13-23 ◽  
Author(s):  
Eamonn A. Gaffney ◽  
Philip K. Maini ◽  
Jonathan A. Sherratt ◽  
Paul D. Dale

Corneal epithelium has a highly specialided wound-healing response. The biological aspects of this repair process are reviewed, and methods of modelling it mathematically are described. A model which focuses on the source of epidermal growth factor (EGF) within a healing wound id described. By considering mathematical representations of a number of possible source terms, it is shown that the EGF presents in the tear film is insufficient to explain the observed rate of healing, and experimental approaches are suggested for distinguishing between other sources. Also, the simulation of exogenous addition of EGF using the miodel is described. An issue that has been the subject of considerable debate in the literature is the role of eyeball curvature. The model is used to show that this curvature is not significant for either the speed or form of healing in the epithelium. In conclusion, a comparison is made between wound healing in the corneal epithelium with that in the epidermis of the skin. Possible diredtions for future modelling work are considered.


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