scholarly journals Developments in silicone technology for use in stoma care

2021 ◽  
Vol 30 (Sup8) ◽  
pp. 7-18
Author(s):  
Thomas Swift ◽  
Gillian Westgate ◽  
Julie Van Onselen ◽  
Stewart Lee
Keyword(s):  
Water Loss ◽  
Wound Care ◽  
Contact Layer ◽  
Transepidermal Water Loss ◽  
Skin Damage ◽  
Wear Time ◽  
Barrier Films ◽  
Moisture Management ◽  
Medical Adhesive ◽  
The University

Soft silicone's flexibility, adhesive capacity and non-toxic, non-odourous and hypoallergenic nature have made it an established material for adhesive and protective therapeutic devices. In wound care, silicone is a component of contact layer dressings for superficial wounds and silicone gel sheeting for reducing the risk of scarring, as well as of barriers for incontinence-associated dermatitis. Regarding stoma accessories, silicone is established in barrier films to prevent contact dermatitis, adhesive removers to prevent skin stripping and filler gels to prevent appliance leaks. Until recently, silicone has not been used in stoma appliances flanges, as its hydrophobic nature has not allowed for moisture management to permit transepidermal water loss and prevent maceration. Traditional hydrocolloid appliances manage moisture by absorbing water, but this can lead to saturation and moisture-associated skin damage (MASD), as well as increased adhesion and resultant skin tears on removal, known as medical adhesive-related skin injury (MARSI). However, novel silicone compounds have been developed with a distinct evaporation-based mechanism of moisture management. This uses colloidal separation to allow the passage of water vapour at a rate equivalent to normal transepidermal water loss. It has been shown to minimise MASD, increase wear time and permit atraumatic removal without the use of adhesive solvents. Trio Healthcare has introduced this technology with a range of silicone-based flange extenders and is working with the University of Bradford Centre for Skin Sciences on prototype silicone-based stoma appliance flanges designed to significantly reduce the incidence of peristomal skin complications, such as MARSI and MASD. It is hoped that this will also increase appliance wear time, reduce costs and improve patient quality of life.

scholarly journals Developments in silicone technology for use in stoma care

2020 ◽  
Vol 29 (6) ◽  
pp. S6-S15 ◽  
Author(s):  
Thomas Swift ◽  
Gillian Westgate ◽  
Julie Van Onselen ◽  
Stewart Lee
Keyword(s):  
Water Loss ◽  
Wound Care ◽  
Contact Layer ◽  
Skin Damage ◽  
Wear Time ◽  
Barrier Films ◽  
Moisture Management ◽  
Skin Tears ◽  
Medical Adhesive ◽  
The University

Soft silicone's flexibility, adhesive capacity and non-toxic, non-odourous and hypoallergenic nature have made it an established material for adhesive and protective therapeutic devices. In wound care, silicone is a component of contact layer dressings for superficial wounds and silicone gel sheeting for reducing the risk of scarring, as well as of barriers for incontinence-associated dermatitis. Regarding stoma accessories, silicone is established in barrier films to prevent contact dermatitis, adhesive removers to prevent skin stripping and filler gels to prevent appliance leaks. Until recently, silicone has not been used in stoma appliances flanges, as its hydrophobic nature has not allowed for moisture management to permit trans-epidermal water loss and prevent maceration. Traditional hydrocolloid appliances manage moisture by absorbing water, but this can lead to saturation and moisture-associated skin damage (MASD), as well as increased adhesion and resultant skin tears on removal, known as medical adhesive-related skin injury (MARSI). However, novel silicone compounds have been developed with a distinct evaporation-based mechanism of moisture management. This uses colloidal separation to allow the passage of water vapour at a rate equivalent to normal trans-epidermal water loss. It has been shown to minimise MASD, increase wear time and permit atraumatic removal without the use of adhesive solvents. Trio Healthcare has introduced this technology with a range of silicone-based flange extenders and is working with the University of Bradford Centre for Skin Sciences on prototype silicone-based stoma appliance flanges designed to significantly reduce the incidence of peristomal skin complications, such as MARSI and MASD. It is hoped that this will also increase appliance wear time, reduce costs and improve patient quality of life.

Use of breathable silicone technology in an ostomy appliance flange

2021 ◽  
Vol 30 (Sup8) ◽  
pp. 25-35
Author(s):  
Peta Lager ◽  
Lisa Loxdale
Keyword(s):  
Preliminary Data ◽  
Transepidermal Water Loss ◽  
User Evaluation ◽  
Skin Damage ◽  
Healthcare Use ◽  
Skin Injury ◽  
Moisture Management ◽  
Peristomal Skin ◽  
Medical Adhesive ◽  
Over Time

Leaks and peristomal skin complications are highly prevalent among people with a stoma, reported by over 80% of ostomates within 2 years of surgery. This suggests that there is room for improvement in ostomy appliances, particularly in their hydrocolloid-based adhesive flanges. Hydrocolloid has an absorptive method of moisture management that, over time, risks maceration and skin stripping, potentially leading to moisture-associated skin damage (MASD) and medical adhesive-related skin injury (MARSI). The newly developed Genii ostomy appliances (Trio Healthcare) use novel Sil2 Breathable Silicone Technology to provide secure, effective adhesion and manage moisture levels by replicating natural transepidermal water loss (TEWL). This has the potential to increase appliance wear time, reduce incidence of MASD and permit atraumatic removal without adhesive remover, reducing the risks of MARSI, as well as time burdens on the user and economic burdens on the healthcare system. Meanwhile, the silicone flanges and water-resistant sports fabric pouches are lightweight, flexible and unobtrusive, and they are the first appliances to be available in colours to match different skin tones, all of which provides security, comfort, confidence and discretion. This article explores the features of Sil2 and Genii ostomy appliances, with reference to preliminary data from a user evaluation.

Using a novel breathable silicone adhesive (Sil2 technology) in stoma appliances to improve peristomal skin health: answering the key questions

2021 ◽  
Vol 30 (Sup8) ◽  
pp. 19-24
Author(s):  
Fiona Le Ber
Keyword(s):  
Skin Damage ◽  
Skin Injury ◽  
Moisture Management ◽  
Silicone Adhesive ◽  
Peristomal Skin ◽  
Medical Adhesive ◽  
Key Questions ◽  
Stoma Care

Fiona Le Ber answers some of the questions that stoma care nurses may have regarding this novel silicone adhesive based technology, which helps to avoid medical adhesive related skin injury (MARSI) and moisture-associated skin damage (MASD). Whereas hydrocolloid stoma appliances absorb moisture, this has a non-absorptive method of moisture management that prevents peristomal skin becoming damp and excoriated.

Using a novel breathable silicone adhesive (Sil2™ technology) in stoma appliances to improve peristomal skin health: answering the key questions

2020 ◽  
Vol 29 (16) ◽  
pp. S16-S21
Author(s):  
Fiona Le Ber
Keyword(s):  
Skin Damage ◽  
Skin Injury ◽  
Moisture Management ◽  
Silicone Adhesive ◽  
Peristomal Skin ◽  
Medical Adhesive ◽  
Key Questions ◽  
Stoma Care

Fiona Le Ber answers some of the questions that stoma care nurses may have regarding this novel silicone adhesive based technology, which helps to avoid medical adhesive related skin injury (MARSI) and moisture-associated skin damage (MASD). Whereas hydrocolloid stoma appliances absorb moisture, this has a non-absorptive method of moisture management that prevents peristomal skin becoming damp and excoriated

Corneocyte Nanotexture as Biomarker for Individual Susceptibility to Skin Irritants

2020 ◽  
Author(s):  
Lars Rüther ◽  
Sanja Kezic ◽  
Christoph Riethmüller
Keyword(s):  
Water Loss ◽  
Transepidermal Water Loss ◽  
Skin Condition ◽  
Individual Risk ◽  
The Novel ◽  
Skin Damage ◽  
Wide Spread ◽  
Individual Susceptibility ◽  
High Degree ◽  
Skin Irritants

Abstract Irritant contact dermatitis is a wide spread occupational skin condition. In addition to generalized protection and teaching schemes, a knowledge about individual risk might add to an improved awareness for hazards. Here, we report on a novel candidate biomarker, which might stage individual susceptibility to irritant skin damage. Subclinical sensitivity was proven in recent studies. As a nano-anatomical measure, it works non-invasively on corneocytes from tape strips. Here, we report on a 7-day course after exposure to sodium lauryl sulphate and compare the novel cell texture index with the classical markers water loss (transepidermal water loss) and natural moisturizing factor. All parameters show a high degree of correlation.

scholarly journals Antioxidant and reduced skin-ageing effects of a polyphenolenriched dietary supplement in response to air pollution: a randomized, double-blind, placebo-controlled study

2021 ◽  
Author(s):  
Vincenzo Nobile ◽  
Irene Schiano ◽  
Ana Peral ◽  
Silvana Giardina ◽  
Eleonora Spartà ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Air Pollution ◽  
Dietary Supplement ◽  
Water Loss ◽  
Air Pollutants ◽  
Transepidermal Water Loss ◽  
Controlled Study ◽  
Skin Damage ◽  
Double Blind ◽  
Pollution Exposure

Background: Air pollution exposure is one of the major threats to skin health and accelerates skin ageing mainly through oxidative stress mechanisms. Since it is difficult to minimize skin exposure to air pollutants, especially in urban areas, strategies to protect the skin are needed. Plant phenolic compounds have been found to be effective in attenuating cellular oxidative stress and inflammation induced by different air pollutants and a dietary approach based on these compounds could provide an efficient protection measure. Objective: Here we investigated the efficacy of a commercially available polyphenol-enriched dietary supplement (Zeropollution®) in reducing pollution-induced oxidative stress and in improving different skin parameters related to skin ageing of Caucasian and Asian subjects exposed to air pollution. Zeropollution is composed of four standardized herbal extracts: Olea europaea leaf, Lippia citriodora, Rosmarinus officinalis, and Sophora japonica. Design: A double-blind randomized, parallel group study was carried out on 100 outdoor workers living in a polluted urban European area (Milan) to assess the efficacy of the dietary supplement. The total antioxidant capacity on saliva (FRAP), the oxidative damage on skin (lipoperoxides content), skin moisturization (corneometer), transepidermal water loss (tewameter), skin radiance and colour (spectrophotometer), skin elasticity (cutometer), skin sebum content (sebumeter), and the skin roughness (image analysis) were measured. Results: Both inter-group and intra-group analysis proved that the dietary supplement improved all clinical and biochemical-monitored parameters, in both Caucasian and Asian individuals. Some of the positive effects such as decreased wrinkle depth, increased elasticity and firmness, improved skin moisturization and transepidermal water loss, and reduced dark spots pigmentation were statistically significant as early as 2 weeks of product consumption. Conclusions: The results of the study indicate reduced oxidative stress-induced skin damage in both Asian and Caucasian women living in a polluted urban area. Therefore, the oral intake of this four-plant based supplement could be considered a complementary nutrition strategy to avoid the negative effects of environmental pollution exposure.

The examination of biophysical parameters of skin (transepidermal water loss, skin hydration and pH value) in different body regions of ponies

2012 ◽  
Vol 15 (3) ◽  
pp. 553-559 ◽  
Author(s):  
M.P. Szczepanik ◽  
P.M. Wilkołek ◽  
M. Pluta ◽  
Ł.R. Adamek ◽  
Z.J.H. Pomorski
Keyword(s):  
Water Loss ◽  
Ph Value ◽  
Neck Region ◽  
Transepidermal Water Loss ◽  
Skin Hydration ◽  
Lumbar Region ◽  
Biophysical Parameters ◽  
Body Regions ◽  
Skin Ph

Abstract The purpose of this study was to evaluate transepidermal water loss, skin hydration and skin pH in normal ponies. Sixteen ponies of both sexes were examined in the study. Measurements were taken from seven different sites: the neck region, the shoulder, thorax, lumbar, inguinal, lip region and the auricle. In each of the regions transepidermal water loss (TEWL), skin hydration and skin pH were measured. For transepidermal water loss, the lowest values were observed in the lumbar region (9.71g/hm2), while the highest values were observed in the lip region (22.35 g/hm2). In the case of skin hydration the lowest values were observed for the thorax region (2.13 CU), and the highest for the lip region (41.81 CU). For skin pH, the lowest results were obtained in the lumbar region (6.93), and the highest in the lip region (7.96).

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