Influence of time on the predictive value of the post-resuscitation ECG

2021 ◽  
Vol 13 (10) ◽  
pp. 424-429
Author(s):  
Carl Evans ◽  
Magnus Nelson

Background: The reliability of the electrocardiogram (ECG) after return of spontaneous circulation (ROSC) is unclear. While its predictive value has previously been described, no studies have looked at the influence of time on the post-ROSC ECG. Aim: This study aimed to evaluate the predictive value of the ECG immediately after ROSC and between 1 and 5 hours later to assess whether time influences its ability to accurately predict the need for percutaneous coronary intervention. Methods: A single-centre, retrospective, observational 1-year analysis examined the records of post-ROSC patients who underwent coronary angiography and for whom prehospital and delayed post-ROSC ECGs were available for analysis. Findings: Forty-two post-ROSC ECGs were reviewed alongside angiographic findings. Sensitivities of 25% and 69%, specificities of 60% and 100% and an accuracies of 33% and 76% were calculated for the prehospital and delayed hospital ECGs respectively. A chi-squared value of 7.78 (P=0.0053) suggests there is statistical significance between the two. Conclusions: The delayed post-ROSC ECG is statistically significantly more accurate, suggesting that time influences the reliability of the post-ROSC ECG.

2012 ◽  
Vol 7 (1) ◽  
pp. 37
Author(s):  
Donald E Cutlip ◽  

Coronary artery disease in patients with diabetes is frequently a diffuse process with multivessel involvement and is associated with increased risk for myocardial infarction and death. The role of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) in patients with diabetes and multivessel disease who require revascularisation has been debated and remains uncertain. The debate has been continued mainly because of the question to what degree an increased risk for in-stent restenosis among patients with diabetes contributes to other late adverse outcomes. This article reviews outcomes from early trials of balloon angioplasty versus CABG through later trials of bare-metal stents versus CABG and more recent data with drug-eluting stents as the comparator. Although not all studies have been powered to show statistical significance, the results have been generally consistent with a mortality benefit for CABG versus PCI, despite differential risks for restenosis with the various PCI approaches. The review also considers the impact of mammary artery grafting of the left anterior descending artery and individual case selection on these results, and proposes an algorithm for selection of patients in whom PCI remains a reasonable strategy.


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