scholarly journals Primary gastric choriocarcinoma - a rare and aggressive tumor with multilineage differentiation: A case report

2019 ◽  
Vol 7 (14) ◽  
pp. 1837-1843 ◽  
Author(s):  
Simona Gurzu ◽  
Constantin Copotoiu ◽  
Alexandra Tugui ◽  
Cedric Kwizera ◽  
Rita Szodorai ◽  
...  
2015 ◽  
Vol 22 (1) ◽  
pp. 112-116
Author(s):  
Amit Agrawal ◽  
Vissa Shanthi ◽  
Baddukonda Appala Ramakrishna ◽  
Kuppili Venkata Murali Mohan

Abstract First characterized by Stroebe, the gliosarcomas are highly malignant and rare primary tumor of the brain composed of neoplastic glial cells in association with spindle cell sarcomatous elements (biphasic tissue patterns). In spite of being recognized as two different pathologies studies have not shown any significant differences between gliosarcoma and glioblastoma with regard to age, sex, size, clinical presentation, and median survival. In summary, gliosarcoma is an aggressive tumor with a propensity to recur and re-grow with poor outcome. Future studies are needed to understand the true pathology of these biphasic tumors.


2020 ◽  
pp. 107815522096567
Author(s):  
Deniz Can Guven ◽  
Saadettin Kilickap ◽  
Hasan Cagri Yildirim ◽  
Furkan Ceylan ◽  
Onur Bas ◽  
...  

Introduction Although, immune check-point inhibitors changed the course of many cancers, the outcomes in sarcomas were rather disappointing with less than 10% response rates. Ewing sarcoma is a poorly differentiated and aggressive tumor mostly seen in the children and adolescents. It’s a distinct type of sarcoma with prominent chemosensitivity in the early stages. However, the relapsing disease has a poor prognosis with limited treatment options. Case report Herein, we represent a case of relapsed Ewing sarcoma treated with multiple lines of chemotherapy. Management & outcome: The patient had a very good response to salvage treatment with a combination of paclitaxel and nivolumab which lasted for twelve months after the cessation of treatment. Discussion We think that chemotherapy plus immunotherapy can be an option for Ewing sarcoma patients treated with multiple lines of chemotherapy.


2019 ◽  
Vol 14 (1) ◽  
pp. 65-67
Author(s):  
Snigdha Rai ◽  
Beemba Shakya

Leiomyosarcoma is a rare but aggressive tumor with poor clinical outcomes in compared to other uterine cancers regardless of its stage. The preoperative diagnosis of leiomyosarcoma is seldom made as the patients present with the symptoms similar to that leiomyoma following hysterectomy and myomectomy. Herein, we present a case of a 50 years old ladyoperated for broad ligament fibroid whose histopathology and immunohistochemistry report revealed leiomyosarcoma. Keywords: fibroid, histopathology, leiomyosarcoma.


2019 ◽  
Vol 45 (2) ◽  
pp. e76-e77
Author(s):  
M. Iturbe ◽  
C. Miliani ◽  
M. De Vega ◽  
C. Rihuete ◽  
C. Naranjo ◽  
...  

2017 ◽  
Vol 6 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Alae Guerrouani ◽  
Mouna Kairouani
Keyword(s):  

2008 ◽  
Vol 8 ◽  
pp. 830-834 ◽  
Author(s):  
Michelle E. Koski ◽  
Jason M. Tedesco ◽  
Peter E. Clark

Primitive neuroectodermal tumor (PNET) of the kidney is a rare and aggressive tumor, often presenting in advanced stages and progressing rapidly. Renal PNET (rPNET) may affect a wide age spectrum, but the majority of cases are in young adults. We present a case of advanced rPNET in a 78-year-old woman. To our knowledge, this is the most advanced age of presentation of this neoplasm to date. We report on her presentation and management, and discuss the current clinical management of this tumor.


GCTs are a locally aggressive tumor that can result in significant pain and dysfunction through the disruption of bony and nearby soft tissue architecture. Although generally benign, these tumors have been shown to have 1-9% chance of metastasis and a local recurrence rate of up to 65%. For these reasons, appropriate treatment is essential to remove primary lesions as well as reduce the odds of metastatic disease and lower recurrence rates. Cryosurgery is a welldescribed technique used to achieve local control of primary GCTs. Modern cryoablation utilizes a cryoprobe to freeze surrounding tissues via release of a thermal conducting gas (argonhelium). The optimal technique for eradication of GCT is a widely debated topic rooted in rates of complications and tumor recurrence. Herein, we describe a case report of a 30-year-old female with a large distal femoral GCT that underwent intralesional curettage and adjunctive cryotherapy utilizing K-Y jelly as a semi-solid medium to transmit the freeze zone more evenly within the cavity. Following cryoablation, the cavity was filled with antibiotic loaded polymethyl methacrylate cement. This technique has scarcely been described in the literature and warrants further investigation.


2019 ◽  
Vol 2 (3) ◽  
pp. 65-68
Author(s):  
Sellami Sahla ◽  
◽  
Ammar Saloua ◽  
Ben Hammouda Saif ◽  
Chaari Chiraz ◽  
...  

Background: Rhabdoid tumor of the kidney is an uncommon and aggressive tumor characterized by poor outcomes. Given the rarity of this tumor, the diagnosis is still a challenge and the treatment are not well codified. Case report: A 4-month-old girl presented with abdominal mass. Clinical and radiologic explorations suggested nephroblastoma. The diagnosis of rhabdoid tumor was made post operatively based on anatomopathological findings.


Author(s):  
Eduardo de Arnaldo Silva Vellutini ◽  
Aldo Eden Cassol Stamm ◽  
Matheus Fernandes de Oliveira

Abstract Introduction Chordoma is a malignant and aggressive tumor originating from remnants of the primitive notochord and usually involving the axial skeleton. Spontaneous regression of clival chordomas was described recently. We present the third case report of spontaneous regression of a clival chordoma and discuss similarities of cases and implications for clinical practice. Case Description We present the case of a previously healthy 21-year-old Caucasian woman who presented with progressive holocranial headache for 3 months, which encouraged image investigation. Magnetic resonance imaging (MRI) revealed an osteolytic clival lesion hyperintense in T2 and hypointense in T1 images. After 2 months of initial evaluation and surgical proposal, she repeated MRI to allow use for intraoperative neuronavigation. Surprisingly, there was tumor regression. Discussion The present reported case is somehow different from previous ones and does not share an underlying inflammatory/immunological recognizable fact, being interpreted by us as a spontaneous partial regression of the tumor. We highlight the need for continuous investigation of chordoma regression to uncover the underlying mechanisms.


1976 ◽  
Vol 7 (5) ◽  
pp. 595-604 ◽  
Author(s):  
Karel Jindrak ◽  
Joseph F. Bochetto ◽  
Laurence I. Alpert

Sign in / Sign up

Export Citation Format

Share Document