scholarly journals A case report of an angiomyxoma in the liver

2018 ◽  
Vol 100 (4) ◽  
pp. e81-e84 ◽  
Author(s):  
AK Malik ◽  
R Filobbos ◽  
A Manoharan ◽  
N Harvey ◽  
DA O’Reilly ◽  
...  
Keyword(s):  
Liver Parenchyma ◽  
Liver Lesion ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Curative Intent ◽  
Right Hemihepatectomy ◽  
History Of ◽  
Size And Morphology ◽  
Disseminated Disease

Angiomyxomas are uncommon myxoid tumours arising most commonly from the pelvis. A 46-year-old woman with a history of polycystic kidney disease presented asymptomatically for surveillance ultrasonography; changes were noted in the size and morphology of her liver cysts. Subsequent radiological assessment displayed features suspicious of malignancy and a right hemihepatectomy was performed with curative intent. Pathological examination of the resected specimen found histology consistent with an angiomyxoma arising primarily from the liver parenchyma. Follow-up review of the patient has been uneventful with annual imaging showing no evidence of recurrence. Angiomyxomas do not characteristically invade other tissues. However, any liver lesion displaying suspicious features of malignancy should be resected in the absence of disseminated disease.

scholarly journals Splenic Involvement in Hereditary Hemorrhagic Telangiectasia

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Susumu Takamatsu ◽  
Kota Sato ◽  
Shunsuke Kato ◽  
Hiroto Nagano ◽  
Shunro Ohtsukasa ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Hereditary Hemorrhagic Telangiectasia ◽  
Epigastric Pain ◽  
Liver Parenchyma ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Recurrent Epistaxis ◽  
Rare Manifestation ◽  
Splenic Involvement ◽  
History Of

A 33-year-old man who presented with prolonged epigastric pain was referred to our hospital. He had experienced recurrent epistaxis and had a family history of hereditary hemorrhagic telangiectasia. Computed tomography and magnetic resonance imaging revealed splenomegaly and a 9 cm hypervascular mass in his spleen. Computed tomography also showed a pulmonary arteriovenous malformation and heterogeneous enhancement of the liver parenchyma, suggesting the presence of arteriosystemic shunts and telangiectases. Based on these findings, the patient was definitely diagnosed with hereditary hemorrhagic telangiectasia according to Curaçao criteria. He underwent splenectomy, and his symptoms disappeared after surgery. Pathological examination of the resected specimen revealed that the hypervascular lesion of the spleen was not a tumor but was composed of abnormal vessels associated with hereditary hemorrhagic telangiectasia. Symptomatic splenic involvement may be a rare manifestation of hereditary hemorrhagic telangiectasia but can be revealed by imaging modalities.

Primary hepatic neuroendocrine tumour masquerading as a giant haemangioma: an unusual presentation of a rare disease

2020 ◽  
Vol 13 (9) ◽  
pp. e236153
Author(s):  
Talal Almas ◽  
Faisal Inayat ◽  
Maryam Ehtesham ◽  
Muhammad Kashif Khan
Keyword(s):  
Neuroendocrine Tumour ◽  
Somatostatin Receptor ◽  
Stable Condition ◽  
Clinical History ◽  
Postoperative Recovery ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Right Hemihepatectomy ◽  
Positron Emission ◽  
Gallium 68

Primary hepatic neuroendocrine tumour is an exceedingly rare entity. We hereby delineate the case of a 45-year-old Balti descent woman who hails from a land-locked village situated in the foothills of the Pakistani Himalayas. The patient presented to our medical centre with a hepatic mass. She underwent extensive diagnostic workup. The consistent findings of an abdominal CT scan, coupled with her clinical history, insinuated a preoperative diagnosis of atypical hepatic haemangioma. After a detailed discussion in a multidisciplinary meeting, a standard right hemihepatectomy was performed. She had an uneventful postoperative recovery and was discharged in stable condition after 1 week. Surprisingly, pathological examination and immunohistochemistry of the resected specimen divulged the diagnosis of a grade II primary hepatic neuroendocrine tumour. Her somatostatin-receptor scintigraphy and Gallium-68 DOTATATE positron emission tomography scan excluded residual hepatic or additional body lesions. Regular follow-ups over the past 4 years demonstrated unremarkable radiological findings with no recurrence to date.

scholarly journals Primary splenic hydatidosis: a case report

2019 ◽  
Vol 48 (2) ◽  
pp. 030006051984550
Author(s):  
Qiang Wang ◽  
Ming-quan Pang ◽  
Ying-li Kang ◽  
Zhi-xin Wang ◽  
Dongzhi Cairang ◽  
...  
Keyword(s):  
Case Report ◽  
Laparoscopic Splenectomy ◽  
Serological Test ◽  
Chronic Atrophic Gastritis ◽  
Pathological Examination ◽  
Test Results ◽  
Imaging Findings ◽  
Pastoral Area ◽  
History Of

We herein report a case of primary splenic hydatidosis to provide data regarding the diagnosis, treatment, and epidemiological statistics of this disease. The patient was from a pastoral area and was diagnosed with primary splenic hydatidosis with chronic atrophic gastritis. The patient had no history of surgical treatment of hydatidosis. The diagnosis was mainly based on possible exposure to endemic areas, imaging findings, serological test results, and operative and pathological examination findings. Laparoscopic splenectomy was performed, and regular albendazole therapy was given after the operation. The patient was admitted to the hospital for gastrointestinal bleeding 3 months postoperatively, and she was successfully treated and discharged. No recurrence of hydatid foci has been observed since the follow-up.

Langerhans Histiocytosis of the Choledochus in an Adult Patient with a History of Disseminated Disease

1988 ◽  
Vol 74 (5) ◽  
pp. 593-597 ◽  
Author(s):  
Saverio Di Palo ◽  
Agostino Faravelli ◽  
Edoardo Beretta ◽  
Gian Luca Taccagni
Keyword(s):  
Electron Microscopy ◽  
Abdominal Pain ◽  
Biliary Obstruction ◽  
Sclerosing Cholangitis ◽  
Pathological Examination ◽  
Complete Clinical Remission ◽  
S 100 ◽  
History Of ◽  
Disseminated Disease ◽  
Liver Immunohistochemistry

A 43 year-old man with a 15-year history of disseminated Langerhans histiocytosis (LH) in complete clinical remission was admitted with jaundice and abdominal pain. Pathological examination demonstrated LH in the choledochus associated with sclerosing cholangitis in the liver. Immunohistochemistry for S-100 protein and electron microscopy of the choledochus tissue showed Langerhans cell-like elements in the infiltrate. Our findings suggest that, in patients with disseminated Langerhans histiocytosis, liver function should be monitored, particularly, for signs of biliary obstruction, and demonstrate that such a finding is possible in adults.

scholarly journals Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Joseph Allencherril ◽  
Sebastian Bruera ◽  
Ronan Allencherril ◽  
Richard J. Hamill
Keyword(s):  
Hepatocellular Carcinoma ◽  
Chest Wall ◽  
Liver Lesion ◽  
Medical Intervention ◽  
Pathological Examination ◽  
Primary Malignancy ◽  
Tissue Mass ◽  
Illicit Substance Use ◽  
History Of ◽  
Chest Mass

Herein we describe the case of an elderly diabetic gentleman presenting with a two-week history of dyspnea and nonproductive cough, found to have a large left anterolateral chest wall mass. Further characterization through computed tomography (CT) of the chest revealed a soft tissue mass in the left anterior lower hemithorax found to be hepatocellular carcinoma (HCC). The liver, spleen, and pancreas were unremarkable. Diagnostic labs were unremarkable. The patient had no history of hepatitis, alcohol abuse, or illicit substance use. Pathological examination and immunohistochemical staining of the chest mass biopsy were consistent with metastatic hepatocellular carcinoma (HCC). The patient opted to pursue no further medical intervention and expired two weeks later. To the authors’ knowledge, this is one of very few descriptions of isolated hepatocellular carcinoma found in the absence of a primary liver lesion and classical risk factors for hepatocarcinogenesis. This case highlights that HCC may present independently of liver lesions seen on imaging in a patient without clear signs or symptoms of liver. HCC should be considered in cases of isolated tumors with unclear primaries as ectopic carcinogenesis and occult primary malignancy are possibilities.

Stage I seminoma: Treatment outcomes in a low-income country.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15024-e15024
Author(s):  
Yazan Asad Abuodeh ◽  
Fadwa Abdelrahman ◽  
Ahmed Abdel-Fattah Salem ◽  
Naim Farah ◽  
Abdelatif Al-Mousa ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Developing Country ◽  
Low Income ◽  
Adjuvant Radiotherapy ◽  
Early Stage ◽  
Pathological Examination ◽  
Cancer Center ◽  
Prior History ◽  
History Of

e15024 Background: The aim of this report is to address treatment outcomes of patients with early-stage seminoma in a developing country with special reference to patients with history of surgical violation of the scrotum and the potential predictors of disease relapse. Methods: Seventy four patients with pure seminoma were treated at King Hussein Cancer Center (Amman, Jordan) between 2003 and 2010. All patients underwent orchiectomy. All but 3 patients received adjuvant radiotherapy. Patients who underwent surgical violation of the scrotum prior to referral were managed by further excision or irradiation of the scrotal scar. The follow-up ranged from 1 to 200 months (mean, 33 months). Results: At the time of follow-up; all but one patient remain alive. The 3-year relapse-free survival for the entire cohort was 95.9%. Three patients were burdened by relapse, all of whom received adjuvant irradiation following inguinal orchiectomy and initially harbored tumors larger than 4cm upon pathological examination. Median time to relapse was 14 months (range, 8-25 months). None were associated with elevated tumor markers prior to detection of relapse. All but one patient were successfully salvaged by chemotherapy. Conclusions: Our results confirm the excellent prognosis for patients with early-stage seminoma treated by orchiectomy and adjuvant radiotherapy in a developing country. Although all patients burdened by relapse demonstrated adverse pathological findings upon initial assessment, no consistent predictor of relapse was found. Scrotal scar re-excision or irradiation in patients with prior history of surgical violation of the scrotum are effective in preventing local failure.

scholarly journals Cervical spinal tuberculosis combined with brucellosis

2020 ◽  
Vol 14 (10) ◽  
pp. 1217-1220
Author(s):  
Guanghai Zhao ◽  
Jing Wang ◽  
Gao Xiang ◽  
Kaisheng Zhou ◽  
Wei Nan ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Spinal Tuberculosis ◽  
Rare Condition ◽  
Pathological Examination ◽  
Segmental Nerve ◽  
Night Sweats ◽  
History Of ◽  
Missed Diagnosis ◽  
Magnetic Resonance Imaging Mri

Introduction: In some developing countries, tuberculosis and brucellosis, which are commom causes of spinal infections, are still common infectious diseases. However, co-occurrence of spinal tuberculosis and brucellosis is rare. Methodology: We report a case a 47-year-old male engaged in aquaculture with a medical history of numbness, weakness, fever, and night sweats in both upper limbs for about 10 days. Serum agglutination test (SAT) for Brucella revealed brucella infection. Cervical computed tomography (CT) scan and magnetic resonance imaging (MRI) suggested C6, C7 vertebral destruction and corresponding segmental nerve compression. Based on preoperative clinical symptoms and auxiliary examination, brucellar spondylitis was first suspected. According to the postoperative pathological examination, the patient was finally diagnosed as cervical spinal tuberculosis combined with brucellosis. Results: The preoperative symptoms of the patient decreased significantly after surgery, and the patient recovered and leaved hospital within two weeks of starting treatment. At the 6-month follow-up, the patient's clinical symptoms completely disappeared, and all laboratory tests returned to normal. Conclusion: Cervical spinal tuberculosis combined with brucellosis is a relatively rare condition. In areas with high rates of tuberculosis and brucellosis, we should conduct comprehensive examinations to avoid misdiagnosis and missed diagnosis.

CEREBELLAR CRYPTOCOCCOMA IN A PATIENT WITH UNDIAGNOSED SARCOIDOSIS

Neurosurgery ◽  
2007 ◽  
Vol 60 (3) ◽  
pp. E571-E571 ◽  
Author(s):  
Charles W. Kanaly ◽  
Lee A. Selznick ◽  
Thomas J. Cummings ◽  
D. Cory Adamson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Brain Tumor ◽  
Clinical Signs ◽  
Pulmonary Nodules ◽  
Underlying Disease ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Predisposing Factor ◽  
History Of

Abstract OBJECTIVE We describe a patient with undiagnosed sarcoidosis who presented with a rare isolated cerebellar cryptococcoma masquerading as a metastatic brain tumor. CLINICAL PRESENTATION A 58-year-old man with a history of resected squamous cell carcinoma of the larynx and pulmonary nodules was found to have a left cerebellar lesion on neuroimaging after presenting with a 4-month history of occipital headaches. Neuroimaging revealed a large, lobulated, intra-axial, left cerebellar hemispheric mass with peripheral nodular enhancement, mild adjacent edema, and dense focal areas of calcification. INTERVENTION The patient underwent a left suboccipital craniotomy for gross total resection of the left cerebellar mass. Pathological examination of the resected specimen demonstrated a cryptococcoma, which was confirmed with a positive cerebrospinal fluid cryptococcal antigen. Postoperative evaluation revealed pulmonary sarcoidosis. CONCLUSION Central nervous system cryptococcoma is a rare infection that may present in a patient with no known history of immunosuppression and no clinical signs of infection. Diagnostically, this can be difficult to distinguish from a brain tumor. Central nervous system cryptococcoma is an opportunistic infection that typically occurs in the presence of an immunosuppressed state. Sarcoidosis should be considered a predisposing factor because patients with this underlying disease have an increased susceptibility to this central nervous system fungal infection.

scholarly journals Female Urethral Diverticulum Carcinoma: A Case Report and Literature Review

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Ryo Kasahara ◽  
Tadashi Tabei ◽  
Yukio Tsuura ◽  
Kazuki Kobayashi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Needle Biopsy ◽  
Ileal Conduit ◽  
Urethral Diverticulum ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Resonance Imaging ◽  
History Of ◽  
Female Urethral Diverticulum ◽  
Gemcitabine And Cisplatin

A 48-year-old woman with a history of voiding difficulty visited our hospital. Magnetic resonance imaging revealed a periurethral tumor, which was pathologically diagnosed as an adenocarcinoma via transperineal needle biopsy. Radical cystectomy and urethrectomy were performed, and the urinary tract was reconstructed using an ileal conduit. Pathological examination of a resected specimen confirmed adenocarcinoma of the urethral diverticulum. The patient received adjuvant gemcitabine and cisplatin chemotherapy. She is alive at 5 months since the operation.

scholarly journals Rare case of combined laryngocoele masquerading as laryngeal carcinoma: a case report and review of literature

2017 ◽  
Vol 4 (1) ◽  
pp. 292
Author(s):  
Gunjan Dwivedi ◽  
Vikas Gupta ◽  
Inderdeep Singh ◽  
Sunil Goyal ◽  
Manoj Kumar ◽  
...  
Keyword(s):  
Rare Case ◽  
Pathological Examination ◽  
Resected Specimen ◽  
Diagnostic Dilemma ◽  
Benign Condition ◽  
Body Sensation ◽  
Normal Voice ◽  
Risk Of Malignancy ◽  
History Of ◽  
Laryngeal Saccule

<p>Laryngocoele is an abnormal dilatation of the laryngeal saccule. It is a rare entity. Patient generally presents with hoarseness, dysphagia, dyspnea, foreign body sensation in throat and swelling in the neck. It is a benign condition, however the risk of malignancy is always associated with it, especially, if a patient is smoker or tobacco chewer. Once the diagnosis is established, laryngocoele are best treated by surgery.<strong> </strong>We present a rare case of combined laryngocoele in a 62 year old male patient, a chronic smoker, with history of recurrent swelling in neck right side for 2 years and hoarseness for duration of 1 month. It was a diagnostic dilemma as to what we were dealing with, a benign condition or malignancy. Eventually patient underwent excision by external approach. Resected specimen histo-pathological examination was consistent with laryngocoele. Post excision his normal voice was also restored.</p>

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