Effects of Panax Ginseng on Quality of Life

2002 ◽  
Vol 36 (3) ◽  
pp. 375-379 ◽  
Author(s):  
Jennifer M Ellis ◽  
Prabashni Reddy

OBJECTIVE: To assess the time-dependent effects of Panax ginseng on health-related quality of life (HRQOL) by use of a general health status questionnaire. METHODS: Subjects were randomized in a double-blind manner to P. ginseng 200 mg/d (n = 15) or placebo (n = 15) for 8 weeks. The Short Form-36 Health Survey version 2 (SF-36v2), a validated general health status questionnaire, was used to assess HRQOL at baseline and at 4 and 8 weeks. HRQOL between the groups was compared by use of repeated-measures analysis of covariance. A p value <0.05 was considered statistically significant. RESULTS: There were no significant differences in baseline demographics and SF-36v2 scores between the groups. After 4 weeks of therapy, higher scores in social functioning ( P. ginseng 54.9 ± 4.6 vs. placebo 49.2 ± 6.5; p = 0.014), mental health ( P. ginseng 52.2 ± 7.7 vs. placebo 47.2 ± 7.3; p = 0.075), and the mental component summary ( P. ginseng 51.3 ± 7.4 vs. placebo 44.3 ± 8.3; p = 0.019) scales were observed in patients randomized to P. ginseng; these differences did not persist to the 8-week time point. The incidence of adverse effects was 33% in the P. ginseng group compared with 17% in the placebo group (p = 0.40). Subjects given P. ginseng (58%) were more likely to state that they received active therapy than subjects given placebo (17%; p < 0.05). CONCLUSIONS: P. ginseng improves aspects of mental health and social functioning after 4 weeks of therapy, although these differences attenuate with continued use.

2014 ◽  
Vol 23 (7) ◽  
pp. 1935-1944 ◽  
Author(s):  
Saku Väätäinen ◽  
Sirkka Keinänen-Kiukaanniemi ◽  
Jouko Saramies ◽  
Hannu Uusitalo ◽  
Jaakko Tuomilehto ◽  
...  

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
P Pijpops ◽  
S Apers ◽  
C Meuleman ◽  
C Tomassetti ◽  
E Dancet

Abstract Study question Which pre-operative endometriosis pain symptom is most troublesome for the quality-of-life of women assessed at different meta-levels? Summary answer Of five pain symptoms chronic pelvic pain is most troublesome or has the strongest correlation to women’s overall quality-of-life and overall and endometriosis-specific health status. What is known already Endometriosis affects women’s quality of life negatively, and its impact seems to depend more on women’s symptoms than on their degree of endometriosis. Experts proposed to include ‘the most troublesome symptom’ and ‘overall pain’ as core outcomes but did not define how to assess these outcomes. It would be interesting to find out which pain symptom (i.e. assessed for presence and intensity) has most impact on women’s quality-of-life assessed at different meta-levels, including: overall quality-of-life (depending on amongst others one’s professional and relational life besides health), general health status and endometriosis-specific health status. Study design, size, duration A prospective survey addressed 277 adult women scheduled for diagnostic and/or therapeutic surgery in a University endometriosis clinic between October 2016 and November 2019. Women were reminded twice of our request to fill out the coded but anonymous questionnaire package assessing five pain symptoms (i.e. chronic pelvic pain, dysmenorrhea, dyspareunia, dysuria and dyschezia) and assessing quality-of-life at three different meta-levels. Participants/materials, setting, methods Women scored five endometriosis symptoms between 0 (no pain) and 10 (worst imaginable pain), combined into ‘overall pain’ (0-50). ‘Overall quality-of-life’ was assessed with the Linear Analogue Scale (LAS; the higher, the better). General and endometriosis-specific health status were assessed with the overall scores of the EuroQol-5D and the Endometriosis-Health-Profile-30 (the higher, the better). Pearson correlation coefficients between the six pain scores and three measures of quality-of-life were computed (p = 0.003; 0.05/18 as Bonferroni correction). Main results and the role of chance A total of 227 women took part (participation rate=82%) and the data of 202 women (mean age 31±5 years old) with surgically confirmed endometriosis were analysed. In the previous six months, the majority of women reported chronic pelvic pain (56%), dyspareunia (55%), dysmenorrhea (56%) and/or dyschezia (58.4%), while only some reported dysuria (25%). Women’s mean overall pain score was 20 (±12). Women’s mean overall quality-of-life was 65 (±16). On average women rated their general health status to be 62 (±18) and their mean endometriosis-specific health status was 53 (±18). Only the pain symptom chronic pelvic pain was correlated (p &lt; 0.001) to assessments of quality-of-Life at all three meta-levels. The correlation for endometriosis-specific health status was large (r= -0.574), while the others were medium (r= -0.343 & r= -0.324). After taking account of the Bonferroni correction for multiple testing the remaining four pain symptoms only had a medium correlation (p &lt; 0.001) to endometriosis-specific health status (r= -0.356 – -0.265; p &lt; 0.001) and they were not correlated to overall quality-of-Life or general health status. Overall pain had a medium correlation (p &lt; 0.001) to Overall quality-of-Life (r= -0.270) and general health status (r= -0.259) and a strong correlation (p &lt; 0.001) to endometriosis-specific health status (r= -0.529). Limitations, reasons for caution The majority of patients (60%) of the recruiting University endometriosis clinic had severe endometriosis (AFS-IV) and this study could be repeated in another setting. Directly asking women which pain symptom is most troublesome to them would be interesting besides exploring correlations between pain symptoms and quality of life. Wider implications of the findings Nurses, midwives and other health care professionals should devote attention to chronic pelvic pain during the anamnesis and women-centred care as this pain symptom is most troublesome for women’s quality of life. Whether surgery decreases chronic pelvic pain and overall pain is currently followed-up in the studied prospective cohort. Trial registration number Not applicable


Author(s):  
David Chadwick

ABSTRACT:In the treatment of the patient with epilepsy not only seizure control but quality of life issues are important aspects of management. Aspects that have an impact on the quality of life include seizure frequency and severity, social functioning, psychological well-being, disease specific measures, and general health status.


2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 8253-8253
Author(s):  
K. M. Gil ◽  
V. E. Von Gruenigen ◽  
H. E. Frasure ◽  
M. Grandon ◽  
M. P. Hopkins ◽  
...  

2020 ◽  
Vol 16 (2) ◽  
pp. 16-22
Author(s):  
O.A. Alifer

Relevance. Hypertension is one of the most common chronic diseases, for which currently the goal of therapy is not so much recovery as improving circulatory function with a satisfactory quality of life. Objective: to determine the impact of different degrees of hypertension on quality of life in female and male patients. Materials and methods. 126 patients with arterial hypertension underwent examination, including 86 women (68%), 40 men (32%) aged 40 to 81 years (mean age 61.9 ± 0.3 years). Arterial hypertension of I degree had 19 people (15.1%), II degree - 65 patients (51.6%), III degree - 42 people (33.3%). The control group consisted of 43 healthy individuals who did not differ from the main group in terms of demographics. Surveys of patients to assess the quality of life conducted with the questionnaire SF-36 (Short Form-36) at each follow-up. Quality of life indicators has value in points. Results. The analysis of quality of life indicators in the group of healthy people found that the level of quality of life in men is much higher than in healthy women: "physical pain", "role functioning" - P1-P2> 0.5; "Physical functioning" - P1-P2 <0.001; "Physical health" - P1-P2> 0.5, except for the scale "general health" - P1-P2 <0.05 (77.2 ± 3.02 vs. 63.75 ± 2.81). The comparison of the quality of life of patients with hypertension of I degree and patients with arterial hypertension of III degrees found reliable differences on the scales "Vitality" (P1-P3 <0.001), and "Social functioning" (P1-P3 <0.5). In patients with II and III degrees of arterial hypertension indicators of quality of life were low in themselves and differed on a scale "role functioning" of the questionnaire: "Vital force" (P2-P3> 0,5); "Role functioning" (P2-P3 <0.5); "Mental health" (P2-P3> 0.5). Patients with hypertension of the I degree in comparison with arterial hypertension of the II degree had reliably higher indicators of quality of life on scales "vital force" (80,0 ± 3,93 points) and "role functioning" (77,1 ± 4,04 points) ), but reduced indicators of "social functioning" and "mental health" (48.7 ± 7.35 and 47.41 ± 2.39 points, respectively). Patients with hypertension of I degree and III degree showed reliable differences on the scales "vital force" (P1-P3 <0.001) and "social functioning" (P1-P3 <0.5); and patients with hypertension of II and III degrees showed a significant decrease in all indicators of quality of life, especially on the scales "social functioning" and "mental health" (up to 31.5 ± 5.19 and up to 40.31 ± 2.23 points, respectively). Patients with hypertension of I degree had a decrease in general health (87.1 ± 3.16), physical function (82.6 ± 2.86), and physical pain (87.1 ± 3.16). Patients with II degree of hypertension had a significant reduction in role functioning (32.4 ± 5.19), physical pain, and general health (36.0 ± 6.12 and 42.26 ± 2.68 points, respectively). Conclusions. Hypertension significantly affects the quality of life. The state of health of patients with hypertension significantly limited their physical activity.


2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0044
Author(s):  
Malik Siddique ◽  
Jayasree Ramaskandhan ◽  
Sultan Qasim

Category: Midfoot/Forefoot Introduction/Purpose: There is paucity of literature comparing foot and general health status including quality of life between patients presenting with Hallux Valgus and Hallux Rigidus. We aimed to compare foot specific patient reported disability and general health status including higher functional activities and quality of life reported between patients presenting with Hallux Valgus and Hallux Rigidus. Methods: All patients who presented at our hospital foot and ankle clinics (between June 2016 and December 2017) with a diagnosis of primary Hallux Valgus or Hallux Rigidus were included in this prospective study. Patients with associated foot problems, bilateral presentations, h/o previous reconstructive surgeries, and underlying neurological conditions were excluded. These patients were grouped based on diagnosis into Group A (Hallux Valgus) and Group B (Hallux Rigidus). In these patients, differences were studied between groups for scores of MOX-FQ Manchester-Oxford foot questionnaire (Domains: Pain, Walking/Standing, Social activities), EQ-5D EuroQol (UK) and Foot and Ankle outcomes scores (FAOS) (Domains: Pain, symptoms, ADL, Recreation, Quality of Life). Statistical tests between groups included tests for normality, student t’tests and chi square tabulation tests using SPSS software. Results: MOX-FQ differences: -  Both groups reported similar level of pain (59.6 ± 22.6 vs. 58.2 ± 23.3); p=0.776; Difficulty with walking/ standing (61.6 vs. 61.4 ); p= 0.960; and restriction with social activity because of foot symptoms (61.6 vs. 59.7 ); p=0.683 EQ-5D: -  For mobility, both groups reported no (21.7% vs. 26.8); slight (28.2% vs. 29.2%) or moderate (34.7% vs. 31.7%) problems; p=0.931. For self-care, pain/discomfort, anxiety/ depression levels, there was no differences between groups; p>0.05. Mean overall general health scores was (71.3 ± 22.8) and (69.5 ± 20.8); p=0.663 FAOS: -  There was no difference in mean pain score (59.6 vs. 58.2; p=0.776), symptoms (70.3 vs. 63.8; p=0.104), ADL score (p=0.587), difficulty with sport/ recreation (p=0.907) or Quality of Life (p=0.662) between groups Conclusion: -  There is no difference in foot related quality of life, general health status and higher functional disability levels between patients presenting with Hallux Valgus vs. Hallux Rigidus. -  The impact of these conditions on disability levels remain the same, amidst the difference in pathology


2020 ◽  
Vol 44 (3) ◽  
pp. 158-165
Author(s):  
Ho Jin Jeong ◽  
Ye Hwang Kim ◽  
Jung Won Yun ◽  
Sang Hwan Oh ◽  
Hyun Seo Yoon ◽  
...  

2020 ◽  
Vol 29 ◽  
Author(s):  
Andréa Fachini da Costa ◽  
Maria Carolina Barbosa Teixeira Lopes ◽  
Cássia Regina Vancini Campanharo ◽  
Ruth Ester Assayag Batista ◽  
Meiry Fernanda Pinto Okuno

ABSTRACT Objective: to assess caregivers’ quality of life and correlate it with elderly people’s quality of life, as well as assess the burden of caregivers of elderly people hospitalized in an Emergency Service and correlate it with their quality of life. Method: this is a cross-sectional and analytical study conducted with 250 caregivers of elderly patients admitted to the Emergency Service of Hospital São Paulo, Brazil, from December 2015 to January 2017. To assess caregivers’ quality of life, the generic Short-Form-36 questionnaire, item short-form health survey was used; burden was assessed using the Zarit Burden Interview. Results: the mean age was 48.36 years, with a predominance of females, most of whon were elderly people’s children. Caregivers showed mild to moderate burden, and in quality of life assessment, the most compromised domains were general health status, vitality, and social aspects. The Short-Form-36 dimensions that had a significant correlation with Zarit Burden Interview scores were physical aspect, general health status, vitality, social aspects, and emotional aspect. Conclusion: caregivers’ quality of live is associated with elderly people’s quality of life. Burden is related to the worsening quality of life of caregivers. It is necessary to identify the work demands and specific needs of caregivers of elderly people in order to develop care strategies involving this population.


Author(s):  
Dilara Sak ◽  
Taygun Dayı ◽  
Erkan Günay ◽  
Adile Öniz

Objective: Effects of regular physical activity on the human health is an important factor for the life quality parameters. The present study aimed to determine effects of moderate aerobic exercise on the life quality and human health. Materials and Methods: There were three groups (competitive cyclists, recreational cyclists and control) who voluntarily participated in this study. The cyclists of the National Bicycle Federation who could continue trainings during the Corona virus pandemic (n: 50), cyclists of the amateur clubs (n: 50) and 50 sedentary adults (≥19 years) were enrolled (n:150). World Health Organization Quality of Life Questionnaire Abbreviated Version - WHOQOL-BREF-TR was used to determine participants' life qualities. Results: Competitive cyclists trained for 13.33 (±7.24) hours per week and they had 4798 min/week MET values. Subgroup scores of WHQOL-BREF-TR (physical, psychological, social, environmental, national environment, general life quality and health) were found to be higher in competitive cyclists than others (recreational cyclists and sedentary adults). In addition, the values of competitive and amateur cyclists in the physical health level parameters were higher than the control group. Competitive cyclists had higher scores for psychological, social health and general life quality subgroups than others (p<0.05). Conclusion: The present study showed that if physical activity level increases, general health status and life quality increase. As a result of the study, it was found that moderate-intensity aerobic exercise (2600-4800 MET-min/week energy expenditure) between 7-13 hours a week supports the protection of general health and has positive effects on life quality. There is a need for future research to determine different exercise types, intensity, frequency and their effects on the general health status and life quality.


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