Concurrent multi-parametric analysis of quantitative dynamic contrast-enhanced MR Imaging and Near-Infrared Spectroscopy in breast lesions

2016 ◽  
Author(s):  
Junqing Xu ◽  
Shudong Jiang ◽  
Yan Zhao ◽  
Ke Wang ◽  
Brian W. Pogue ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Mr Imaging ◽  
Near Infrared Spectroscopy ◽  
Parametric Analysis ◽  
Near Infrared ◽  
Breast Lesions ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced

scholarly journals Assessing tumor physiology by dynamic contrast-enhanced near-infrared spectroscopy

2013 ◽  
Author(s):  
Kyle Verdecchia ◽  
Jonathan Elliott ◽  
Mamadou Diop ◽  
Lisa Hoffman ◽  
Ting-Yim Lee ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced

scholarly journals Cerebral perfusion and blood–brain barrier assessment in brain trauma using contrast-enhanced near-infrared spectroscopy with indocyanine green: A review

2020 ◽  
Vol 40 (8) ◽  
pp. 1586-1598 ◽  
Author(s):  
Mario Forcione ◽  
Antonio M Chiarelli ◽  
David J Davies ◽  
David Perpetuini ◽  
Piotr Sawosz ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Indocyanine Green ◽  
Blood Brain Barrier ◽  
Near Infrared Spectroscopy ◽  
Trauma Care ◽  
Near Infrared ◽  
Clinical Status ◽  
Brain Trauma ◽  
Future Studies ◽  
Contrast Enhanced

Contrast-enhanced near-infrared spectroscopy (NIRS) with indocyanine green (ICG) can be a valid non-invasive, continuous, bedside neuromonitoring tool. However, its usage in moderate and severe traumatic brain injury (TBI) patients can be unprecise due to their clinical status. This review is targeted at researchers and clinicians involved in the development and application of contrast-enhanced NIRS for the care of TBI patients and can be used to design future studies. This review describes the methods developed to monitor the brain perfusion and the blood–brain barrier integrity using the changes of diffuse reflectance during the ICG passage and the results on studies in animals and humans. The limitations in accuracy of these methods when applied on TBI patients and the proposed solutions to overcome them are discussed. Finally, the analysis of relative parameters is proposed as a valid alternative over absolute values to address some current clinical needs in brain trauma care. In conclusion, care should be taken in the translation of the optical signal into absolute physiological parameters of TBI patients, as their clinical status must be taken into consideration. Discussion on where and how future studies should be directed to effectively incorporate contrast-enhanced NIRS into brain trauma care is given.

Breast Lesions: Evaluation with Dynamic Contrast-enhanced T1-weighted MR Imaging and with T2*-weighted First-Pass Perfusion MR Imaging

Radiology ◽  
2000 ◽  
Vol 216 (2) ◽  
pp. 545-553 ◽  
Author(s):  
Kjell A. Kvistad ◽  
Jana Rydland ◽  
Jari Vainio ◽  
Hanne B. Smethurst ◽  
Steinar Lundgren ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Breast Lesions ◽  
Dynamic Contrast Enhanced ◽  
Pass Perfusion ◽  
Contrast Enhanced ◽  
First Pass ◽  
Perfusion Mr ◽  
Perfusion Mr Imaging ◽  
First Pass Perfusion

Contrast-Enhanced Ultrasound and Near-Infrared Spectroscopy of the Neonatal Bowel: Novel, Bedside, Noninvasive, and Radiation-Free Imaging for Early Detection of Necrotizing Enterocolitis

2018 ◽  
Vol 35 (14) ◽  
pp. 1358-1365 ◽  
Author(s):  
Suzanne Al-Hamad ◽  
David Hackam ◽  
Seth Goldstein ◽  
Thierry Huisman ◽  
Kassa Darge ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Early Detection ◽  
Necrotizing Enterocolitis ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Morbidity And Mortality ◽  
Contrast Enhanced Ultrasound ◽  
Noninvasive Technique ◽  
Initial Development ◽  
Contrast Enhanced

AbstractDespite extensive research and improvements in the field of neonatal care, the morbidity and mortality associated with necrotizing enterocolitis (NEC) have remained unchanged over the past three decades. Early detection of ischemia and necrotic bowel is vital in improving morbidity and mortality associated with NEC; however, strategies for predicting and preventing NEC are lacking. Contrast-enhanced ultrasound (CEUS) and near-infrared spectroscopy (NIRS) are novel techniques in pediatrics that have been proven as safe modalities. CEUS has benefits over conventional ultrasound (US) by its improved real-time evaluation of the micro- and macrovascularities of normally and abnormally perfused tissue. US has been implemented as a useful adjunct to X-ray for earlier evaluation of NEC. NIRS is another noninvasive technique that has shown promise in improving early detection of NEC. The purpose of this article is to review the current understanding of changes in bowel perfusion in NEC, discuss the accuracy of abdominal US in detecting NEC, and explain how the use of CEUS and NIRS will enhance the precise and early detection of altered/pathological bowel wall perfusion in the initial development and course of NEC.

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