Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases

Objective: the present study was aimed to evaluate the role of pharmaceutical services in improving the outcome of mineral bone disorder in patients with advanced chronic kidney disease. Methodology: One hundred and twenty patients with chronic kidney disease-mineral bone disorder (CKD-MBD) screened for eligibility, seventy-six patients enrolled in the study and randomly allocated into two groups: pharmaceutical care and usual care, both groups interviewed by the pharmacist using specific questionnaire for assessing the quality of life (QoL). All the drug related problems (DRPs) including drug-drug interactions (DDIs) were recorded by the pharmacist. Blood samples were collected and utilized for analyzing the levels of vitamin D, phosphorous, calcium, albumin and parathyroid hormone at baseline and three months after. The pharmaceutical care group received all the educations about their medications and how to minimize DRPs; improve the QoL. Additionally, the pharmaceutical intervention included correcting the biochemical parameters. Results: Pharmaceutical care significantly improved patients QoL and minimized DRPs and DDIs. It was also effective in improving the biochemical parameters. Conclusion: Pharmaceutical care has a positive impact on improving the outcome of patients with CKD-MBD through attenuating DRPs, improving the biochemical parameters and the QoL.

Download Full-text

The key role of renin blockade in chronic kidney disease

Primary Care Cardiovascular Journal (PCCJ) ◽

10.3132/pccj.2009.031 ◽

2009 ◽

Vol 2 (1) ◽

pp. 21

Author(s):

Alan Begg

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease

Download Full-text

Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction

Case Medical Research ◽

10.31525/ct1-nct03960073 ◽

2019 ◽

Author(s):

Keyword(s):

Heart Failure ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

Ejection Fraction ◽

Mitochondrial Dysfunction ◽

Preserved Ejection Fraction

Download Full-text

Faculty Opinions recommendation of The role of salt intake and salt sensitivity in the management of hypertension in South Asian people with chronic kidney disease: a randomised controlled trial.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718019587.793481659 ◽

2013 ◽

Author(s):

David Goldsmith

Keyword(s):

Chronic Kidney Disease ◽

Randomised Controlled Trial ◽

Kidney Disease ◽

South Asian ◽

Salt Intake ◽

Controlled Trial ◽

Salt Sensitivity ◽

Randomised Controlled ◽

Asian People

Download Full-text

Faculty Opinions recommendation of Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin?

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718176700.793500199 ◽

2014 ◽

Author(s):

Jorge Cannata-Andía

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Bone Disease ◽

Adynamic Bone Disease ◽

Dietary Phosphate ◽

Adynamic Bone

Download Full-text

Faculty Opinions recommendation of Flexible ureterorenoscopy is safe and efficient for the treatment of kidney stones in patients with chronic kidney disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.719711802.793500645 ◽

2014 ◽

Author(s):

M Hammad Ather

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Kidney Stones ◽

Flexible Ureterorenoscopy

Download Full-text

Role of Vitamin D in Vascular Complications and Vascular Access Outcome in Patients with Chronic Kidney Disease

Current Medicinal Chemistry ◽

10.2174/0929867323666160405112019 ◽

2016 ◽

Vol 23 (17) ◽

pp. 1698-1707 ◽

Cited By ~ 7

Author(s):

Domenico Santoro ◽

Vincenzo Pellicanò ◽

Valeria Cernaro ◽

Viviana Lacava ◽

Antonio Lacquaniti ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Vitamin D ◽

Kidney Disease ◽

Vascular Access ◽

Vascular Complications

Download Full-text

Hyperuricemia and Cardiovascular Disease

Current Pharmaceutical Design ◽

10.2174/1381612825666190408122557 ◽

2019 ◽

Vol 25 (6) ◽

pp. 700-709 ◽

Cited By ~ 4

Author(s):

Shuangshuang Zhang ◽

Yong Wang ◽

Jinsong Cheng ◽

Ning Huangfu ◽

Ruochi Zhao ◽

...

Keyword(s):

Cardiovascular Disease ◽

Metabolic Syndrome ◽

Chronic Kidney Disease ◽

Uric Acid ◽

Kidney Disease ◽

Kidney Stones ◽

Treatment Plan ◽

Circulatory System ◽

Special Focus ◽

Positive Effects

Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research. In this review, we summarize the recent knowledge about hyperuricemia, with a special focus on its physiology, epidemiology, and correlation with cardiovascular disease. This review also discusses the possible positive effects of treatment to reduce urate levels in patients with cardiovascular disease and hyperuricemia, which may lead to an improved clinical treatment plan.

Download Full-text