A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

In total knee arthroplasty (TKA) the implant design is one key factor for a proper functional restoration of the diseased knee. Therefore, detailed knowledge on the shape (morphology) is essential to guide the design process. In literature, the morphology has been extensively studied revealing differences, e.g. between ethnicity and gender. However, it is still unclear in which way gender-specific morphological differences are sexual dimorphism or explained by differences in size.The aim of this study was to investigate the morphology of the distal femur under gender-specific aspects for a large group of patients. Statistical analysis was used to reveal significant differences and subsequent correlation analysis to normalize the morphology.A dataset of n=363 segmented distal femoral bone surface reconstructions (229 female, 134 male) were randomly collected from a database of patients which underwent TKA. In total, 34 morphological features (distances, angles), quantifying the distal femoral geometry, were determined full automatically. Subsequently, graphs and descriptive statistics were used to check normality and gender-specific differences were analyzed by calculating the 95% confidence intervals for women and men separately. Finally, significant differences were normalized by dividing each feature by appropriate distance measurements and confidence intervals were recalculated.Looking at the confidence 95% intervals, 6 of 34 features did not show any significant differences between genders. Remarkably, this primarily involves angular (relative) features whereas distance (absolute) measurements were mostly gender dependent. Then, we normalized all distance measurements and radii according to their direction of measurement: Features defined in medial/lateral (ML) direction were divided by the overall ML width and those following the anterior/posterior direction were normalized based on the overall AP length. The results demonstrated that gender- specific differences mostly disappear by using an adequate normalization term.In conclusion, implant sizes (femoral components) should not be linearly scaled according to one dimension. Instead, ML and AP directions should be regarded separately (non-isotropic scaling). Taking this into consideration, gender-specific differences might be neglected.

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742 Age and gender specific differences in left ventricular geometry and function, and pulmonary artery pressure in chronic dialysis patients in New Mexico, USA

European Journal of Heart Failure Supplements ◽

10.1016/s1567-4215(03)90480-2 ◽

2003 ◽

Vol 2 (1) ◽

pp. 158

Author(s):

V RAIZADA ◽

R TAYLOR ◽

W LUO ◽

M VIGIL ◽

A HARFORD ◽

...

Keyword(s):

New Mexico ◽

Left Ventricular ◽

Left Ventricular Geometry ◽

Dialysis Patients ◽

Age And Gender ◽

Ventricular Geometry ◽

Gender Specific Differences ◽

And Gender ◽

And Function ◽

Gender Specific

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Acceptance of wearable fitness devices in developing countries: exploring the country and gender-specific differences

Journal of Asia Business Studies ◽

10.1108/jabs-11-2020-0456 ◽

2021 ◽

Vol ahead-of-print (ahead-of-print) ◽

Author(s):

Shweta Pandey ◽

Deepak Chawla ◽

Sandeep Puri ◽

Luz Suplico Jeong

Keyword(s):

Developing Countries ◽

The Philippines ◽

Individual Characteristics ◽

Partial Least Square ◽

Future Research ◽

Content Type ◽

Gender Specific Differences ◽

And Gender ◽

The Impact ◽

Gender Specific

Purpose Notwithstanding the novelty and importance of wearable fitness devices, few studies have focussed on comparing the drivers of adoption and usage of wearable fitness in the context of developing countries. This study aims to explore factors that drive overall acceptance of wearable fitness devices in developing countries (India and the Philippines) and whether the impact of these factors on the intention to adopt (INT) differs by country and gender. Design/methodology/approach The study extends the existing body of knowledge by developing a model that integrates the impact of various perceived benefits (health, autonomy, social, hedonic, symbolic), health self-efficacy (HEALTHSE) and individual characteristics (technological innovativeness [TI]) on the INT wearable fitness devices and the moderating impact of country and gender. The analysis was carried out using partial least square and data of 343 respondents. Findings This study finds that the INT wearable fitness devices by consumers in developing countries are positively impacted by hedonic, health and autonomy, HEALTHSE and TI. Symbolic and social factors do not have any significant impact on the overall INT wearable fitness devices. However, there are country and gender-specific differences that are consequential to the development of marketing strategies. Research limitations/implications The framework and results are specific to the two countries and limited by convenience sampling. Future research can focus on replication across different countries and extend the model with additional contextual factors such as perceived risks. Originality/value To the best knowledge of the authors, this is one of the few studies to examine and compare the drivers of adoption of wearable fitness devices in lesser researched developing countries. Also, it is one of the few studies to compare the moderating impact of country and gender in the context of the INT wearable devices. The study provides a theoretical and methodological foundation for future research, as well as practical implications for global companies developing and promoting wearable fitness devices.

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