scholarly journals Expression and New Exon Mutations of the Human Beta Defensins and Their Association on Colon Cancer Development

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0126868 ◽  
Author(s):  
Abdelhabib Semlali ◽  
Abdullah Al Amri ◽  
Arezki Azzi ◽  
Omair Al Shahrani ◽  
Maha Arafah ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Development ◽  
Beta Defensins

A combination of omega-3 fatty acids and a butyrate-producing fiber mitigates colon cancer development

2006 ◽  
Author(s):  
Dr. Joanne R. Lupton ◽  
Dr. Nancy D. Turner ◽  
Dr. Leslie Braby ◽  
Dr. John Ford ◽  
Dr. Raymond J. Carroll ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Colon Cancer ◽  
Cancer Development ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Tu1985 Loss of Integrin β6 (ITGB6) Protects From Colon Cancer Development In Vivo

2015 ◽  
Vol 148 (4) ◽  
pp. S-953
Author(s):  
Susan Bengs ◽  
Marianne R. Spalinger ◽  
Stephanie Kasper ◽  
Silvia Lang ◽  
Isabelle Frey-Wagner ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Development

scholarly journals Synchronous NET and colorectal cancer development: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Shinsei Yumoto ◽  
Yuji Miyamoto ◽  
Takahiko Akiyama ◽  
Yuki Kiyozumi ◽  
Kojiro Eto ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Colon Cancer ◽  
Systemic Therapy ◽  
Multiple Organ ◽  
Cancer Development ◽  
Sigmoid Colon Cancer ◽  
Synchronous Tumors ◽  
Case Presentation ◽  
The Difference ◽  
Rectal Neuroendocrine Tumor

Abstract Background The incidence of synchronous gastrointestinal neuroendocrine tumors (GI-NETs) and colorectal cancer is very low. Case presentation We present a 72-year-old man diagnosed with a rectal neuroendocrine tumor (NET) with multiple organ metastases and simultaneous sigmoid colon cancer. Although the NET was his prognostic factor, he underwent a laparoscopic sigmoidectomy at first because it was expected that the colon cancer would cause obstruction or bleeding during NET treatment. Subsequently, he started taking everolimus. Conclusions We should consider surgical resection of the synchronous cancer before systemic therapy for a GI-NET regardless of the difference in prognosis between synchronous tumors, if the cancer may impair the continuation of systemic therapy.

scholarly journals Genome-Wide Screening of Genes Regulated by DNA Methylation in Colon Cancer Development

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e46215 ◽  
Author(s):  
Sándor Spisák ◽  
Alexandra Kalmár ◽  
Orsolya Galamb ◽  
Barna Wichmann ◽  
Ferenc Sipos ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Colon Cancer ◽  
Cancer Development ◽  
Genome Wide

scholarly journals Chemopreventive effect of chalcone derivative, L2H17, in colon cancer development

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Shanmei Xu ◽  
Minxiao Chen ◽  
Wenbo Chen ◽  
Junguo Hui ◽  
Jiansong Ji ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Development ◽  
Chalcone Derivative ◽  
Chemopreventive Effect

scholarly journals Screening and Functional Analysis of Hub MicroRNAs Related to Tumor Development in Colon Cancer

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Dong-Hu Yu ◽  
Wei Li ◽  
Jing-Yu Huang ◽  
Xiao-Ping Liu ◽  
Chi Zhang ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Functional Analysis ◽  
Gene Networks ◽  
Target Genes ◽  
Bioinformatics Analysis ◽  
Tumor Development ◽  
Therapeutic Targets ◽  
Cancer Development ◽  
Candidate Mirnas ◽  
The Future

Various microRNAs (miRNAs) are of importance in the development of colon cancer, but most of the mechanisms of the miRNAs are still unclear. In order to clarify the hub miRNAs and their roles in colon cancer development, GSE98406 was used to screen hub miRNAs by bioinformatics analysis. 46 DE-miRNAs (14 were upregulated and 32 were downregulated) and 1738 target genes of DE-miRNAs were ascertained. miRNAs-gene-networks and miRNAs-GO-networks were built to get more knowledge about the function of candidate miRNAs. After validation, three miRNAs (miR-17-5p, miR-182-5p and miR-200a-3p) were recognized to be hub miRNAs associated with the progression of colon cancer. More importantly, the hub miRNAs and the putative targets genes might be new diagnostic and therapeutic targets for colon cancer in the future.

scholarly journals Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development

2019 ◽  
Vol 10 (6) ◽  
Author(s):  
Xiaoyu Liu ◽  
Peng Zhang ◽  
Chuanming Xie ◽  
Kathy W. Y. Sham ◽  
Simon S. M. Ng ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Development
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