scholarly journals Clinicopathological Characteristics of Mucinous Breast Cancer: A Retrospective Analysis of a 10-Year Study

PLoS ONE ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. e0155132 ◽  
Author(s):  
Lei Lei ◽  
Xingfei Yu ◽  
Bo Chen ◽  
Zhanhong Chen ◽  
Xiaojia Wang
2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e13095-e13095
Author(s):  
Lei Lei ◽  
Xingfei Yu ◽  
Bo Chen ◽  
zhan-Hong Chen ◽  
Xiaojia Wang

Author(s):  
Wanting Shao ◽  
Christina Kuhn ◽  
Doris Mayr ◽  
Nina Ditsch ◽  
Magdalena Kailuwait ◽  
...  

Abstract Purpose The aim of this study was to investigate the expression of liver X receptors α/β (LXR) in primary breast cancer (BC) tissues and to analyze its correlations with clinicopathological parameters including patient survival. Methods In a well-characterized cohort of 305 primary BC, subcellular distribution of LXR was evaluated by immunohistochemistry. Correlations with clinicopathological characteristics as well as with patient outcome were analyzed. Results LXR was frequently localized in both nuclei and cytoplasms of BC cells, with stronger staining in nuclei. Total and nuclear LXR expression was positively correlated with ER and PR status. Overall survival analysis demonstrated that cytoplasmic LXR was significantly correlated with poor survival and appeared as an independent marker of poor prognosis, in stage I but not in stage II–III tumors Conclusion Altogether, these data suggest that cytoplasmic LXR could be defined as a prognostic marker in early stage primary BC.


2013 ◽  
Vol 11 ◽  
pp. S79-S83 ◽  
Author(s):  
Francesca Rovera ◽  
Matteo Lavazza ◽  
Stefano La Rosa ◽  
Anna Fachinetti ◽  
Corrado Chiappa ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document