scholarly journals Determinants of soil-transmitted helminth infections among pre-school-aged children in Gamo Gofa zone, Southern Ethiopia: A case-control study

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243836
Author(s):  
Mekuria Asnakew Asfaw ◽  
Teklu Wegayehu ◽  
Tigist Gezmu ◽  
Alemayehu Bekele ◽  
Zeleke Hailemariam ◽  
...  

Background Pre-school aged children (PSAC) are highly affected by soil-transmitted helminths (STH), particularly in areas where water, sanitation, and hygiene (WASH) are inadequate. Context-specific evidence on determinants of STH infections in PSAC has not been well established in the study area. This study, therefore, aimed to fill these gaps in Gamo Gofa zone, Southern Ethiopia. Methods A community-based unmatched case-control study, nested in a cross-sectional survey, was conducted in January 2019. Cases and controls were identified based on any STH infection status using the Kato-Katz technique in stool sample examination. Data on social, demographic, economic, behavioral, and WASH related variables were collected from primary caregivers of children using pre-tested questionnaire. Determinants of STH infections were identified using multivariable logistic regression model using SPSS version 25. Results A total of 1206 PSAC (402 cases and 804 controls) participated in this study. Our study showed that the odds of STH infection were lowest among PSAC living in urban areas (AOR = 0.55, 95% CI: 0.39–0.79), among those from households with safe water source (AOR = 0.67, 95% CI: 0.47–0.0.93), and in those PSAC from households with shorter distance from water source (<30 minutes) (AOR = 0.51, 95% CI: 0.39–0.67). On the other hand, the odds of STH infection were highest among PSAC from households that had no functional hand washing facility (AOR = 1.36, 95% CI: 1.04–1.77), in those PSAC from households that had unclean latrine (AOR: 1.82, 95% CI: 1.19–2.78), and among those PSAC under caregivers who had lower score (≤5) on knowledge related to STH transmission (AOR = 1.85, 95% CI: 1.13–3.01). Conclusions Given efforts required eliminating STH by 2030; the existing preventive chemotherapy intervention should be substantially strengthened with WASH and behavioral interventions. Thus, an urgent call for action is required to integrate context-specific interventions, particularly in rural areas.

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Harriet Mpairwe ◽  
Milly Namutebi ◽  
Gyaviira Nkurunungi ◽  
Pius Tumwesige ◽  
Irene Nambuya ◽  
...  

Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5–17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertiary education for fathers (adjusted OR (95% CI); 2.32 (1.71–3.16)) and mothers (1.85 (1.38–2.48)); area of residence at birth, with children born in a small town or in the city having an increased asthma risk compared to schoolchildren born in rural areas (2.16 (1.60–2.92)) and (2.79 (1.79–4.35)), respectively; father’s and mother’s history of asthma; children’s own allergic conditions; atopy; and cooking on gas/electricity. In conclusion, asthma was associated with a strong rural-town-city risk gradient, higher parental socio-economic status and urbanicity. This work provides the basis for future studies to identify specific environmental/lifestyle factors responsible for increasing asthma risk among children in urban areas in LMICs.


2014 ◽  
Vol 3 (3) ◽  
pp. 185 ◽  
Author(s):  
Fikru Tesfaye ◽  
Alemu Tamiso ◽  
Yemane Birhan ◽  
Tariku Tadele

<p>As part of the overall package of maternal and child health services in Ethiopia, all children are provided with free immunization services and it is available in all government health facilities, both in rural and urban areas. But significant number of children was defaulted from Immunization schedule, even after the health extension program was launched. Therefore, the study was assessed predictors of immunization defaulting among children age range of 12-23 months, in Hawassa Zuria district of southern Ethiopia. Unmatched case control study was conducted in six Kebeles which were selected from 26 kebeles by simple random sampling techniques. Cases were children in the age ranges of 12 - 23 months who did not complete the recommended immunization. All cases (105) and controls (209) in the kebeles were identified by using health posts Vaccine registration book. Bivariable and multiple logistic regression model were used to identify important predictor of immunization defaulting. P-value of less than 0.05 was considered as the level of significances. The study identified educational status, place of delivery, immunization related knowledge, ANC follow up and household wealth status as significant predictors of defaulting from immunization schedules. Sustained health education on vaccination related knowledge and institutional delivery services utilization will be needed. The household literacy and economic status should also get emphasis so as to decreases defaulting of children from immunization schedule.</p>


2001 ◽  
Vol 126 (3) ◽  
pp. 389-396 ◽  
Author(s):  
M. C. PUECH ◽  
J. M. McANULTY ◽  
M. LESJAK ◽  
N. SHAW ◽  
L. HERON ◽  
...  

From December 1997 to April 1998, 1060 laboratory-confirmed cryptosporidiosis cases were reported in New South Wales, Australia. In a case-control study, compared with 200 controls, the 100 cases were younger (mean age 4·2 versus 7·1 years; P < 0·0001), more likely to report swimming at a public pool (59% versus 38%; adjusted OR and 95% CI = 2·7; 1·4–5·1) and swimming in a dam, river or lake (OR = 4·8; 1·1–20·3) but less likely to report drinking bottled water (OR = 0·4; 0·2–0·9). In subgroup analyses, in rural areas illness was associated mainly with contact with another person with diarrhoea, and in urban areas illness was associated with swimming in a public pool. Cryptosporidium oocysts were more commonly detected in pools to which at least two notified cases had swum (P = 0·04). Outbreaks of cryptosporidiosis can be prolonged, involve multiple pools and be difficult to control.


2014 ◽  
Vol 3 (3) ◽  
pp. 185 ◽  
Author(s):  
Fikru Tesfaye ◽  
Alemu Tamiso ◽  
Yemane Birhan ◽  
Tariku Tadele

<p>As part of the overall package of maternal and child health services in Ethiopia, all children are provided with free immunization services and it is available in all government health facilities, both in rural and urban areas. But significant number of children was defaulted from Immunization schedule, even after the health extension program was launched. Therefore, the study was assessed predictors of immunization defaulting among children age range of 12-23 months, in Hawassa Zuria district of southern Ethiopia. Unmatched case control study was conducted in six Kebeles which were selected from 26 kebeles by simple random sampling techniques. Cases were children in the age ranges of 12 - 23 months who did not complete the recommended immunization. All cases (105) and controls (209) in the kebeles were identified by using health posts Vaccine registration book. Bivariable and multiple logistic regression model were used to identify important predictor of immunization defaulting. P-value of less than 0.05 was considered as the level of significances. The study identified educational status, place of delivery, immunization related knowledge, ANC follow up and household wealth status as significant predictors of defaulting from immunization schedules. Sustained health education on vaccination related knowledge and institutional delivery services utilization will be needed. The household literacy and economic status should also get emphasis so as to decreases defaulting of children from immunization schedule.</p>


2019 ◽  
Author(s):  
Harriet Mpairwe ◽  
Milly Namutebi ◽  
Gyaviira Nkurunungi ◽  
Pius Tumwesige ◽  
Irene Nambuya ◽  
...  

AbstractData on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5-17years) in urban Uganda. We conducted a case-control study, enrolling 561 cases and 1,139 controls. Asthma was diagnosed by study clinicians.The main risk factors for asthma were tertiary education for fathers [adjusted OR (95% CI); 2.49 (1.89-3.29)] and mothers [2.14 (1.64-2.78)]; area of residence at birth, with children born in a small town or in the city having an increased asthma risk compared to schoolchildren born in rural areas [2.00 (1.49-2.68)] and [2.82 (1.85-4.30)], respectively; father’s and mother’s history of asthma; children’s own allergic conditions; atopy; and using gas/electricity for indoor cooking.Asthma was associated with a strong rural-town-city risk gradient, higher parental socio-economic status and urbanicity. This work provides the basis for future studies to identify specific environmental/lifestyle factors responsible for increasing asthma risk among children in urban areas in LMICs.


2020 ◽  
Vol 32 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Keiichiro IKEDA ◽  
Taku HARADA ◽  
Yoko TARUMI ◽  
Hirotaka OCHIAI ◽  
Takako SHIRASAWA ◽  
...  

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