scholarly journals SERUM URIC ACID LEVEL IN ACUTE ISCHAEMIC STROKE

2013 ◽  
Vol 2 (36) ◽  
pp. 6915-6926
Author(s):  
Arvind Charan Mangal ◽  
Rishi T Guria ◽  
Manish Kumar Singh
Keyword(s):  
Uric Acid ◽  
Ischaemic Stroke ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acute Ischaemic Stroke ◽  
Acid Level ◽  
Serum Uric Acid Level

scholarly journals A study to find out relationship in between serum uric acid level and stroke

2017 ◽  
Vol 4 (5) ◽  
pp. 1255
Author(s):  
Vishwa Deepak Tripathi ◽  
Zakir Hussain
Keyword(s):  
Uric Acid ◽  
Ischaemic Stroke ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acute Ischaemic Stroke ◽  
Acid Level ◽  
Significant Positive Correlation ◽  
Serum Uric Acid Level ◽  
Normal Serum ◽  
Stroke Patients

Background: The role of uric acid as a risk factor in cases of acute ischaemic stroke is controversial. The present study was conducted with the aim to study the clinical profile and the incidence of stroke in patients with normal and elevated uric acid and its correlation with other risk factors.Methods: This study was conducted in 100 patients with acute ischaemic stroke who were admitted in NSCB Hospital Jabalpur from August 2009 to July 2010.Clinical records of patients and their serum uric acid level was investigated. The severity of neurological deficit was recorded according to the scandinavian stroke scale (SSS). Patients were followed up during hospital stay and outcome was graded by using modified Rankin’s scale (mRS). Finally, collected data were analyzed using Chi square and student t test wherever appropriate. P value <0.05 was considered significant.Results: A total of 100 patients were included in the study. Majority of the patients (57%) were in the age group of 50 to 70 years. Males (54%) were more affected than females (46%). Out of 100, 71 had normal serum uric acid levels in which 35 (49%) patients were above 60 years of age. 29 of them had hyperuricemia in which 20 (69%) were above the age of 60 years. Of 54 males and 46 females hyperuricemia was observed in 16 (55%) and 13 (45%) patients respectively. A significant correlation was observed between hyperuricemia and hypertension (p<0.05). Non-significant correlation was seen between hyperuricemia, diabetes and hyperlipidemia (p>0.05). Significant, positive correlation p<0.05 was present amongst male alcoholics. Association of uric acid with smoking in acute ischaemic stroke patients was found to be statistically insignificant (p>0.05). Majority (83%) of patients were having infarct in MCA artery territory. Majority of patients 20 (69%) with elevated serum uric acid were having SSS score >30. Statistically insignificant (p>0.05) association was observed between mean mRS score in patients with normal serum uric acid Vs patients with hyperuricemia.Conclusions: The prevalence of hyperuricemia in acute ischaemic stroke patients was lower than in normal population. Age, hypertension and alcoholism amongst males showed statistically significant positive correlation with hyperuricemia in patient with acute ischaemic stroke and hence they are considered to be the significant risk factors.

scholarly journals Association of Serum Uric acid with Recent Ischaemic Stroke

2019 ◽  
Vol 2 (1) ◽  
pp. 21-26
Author(s):  
Suraj Gyawali
Keyword(s):  
Uric Acid ◽  
Ischemic Stroke ◽  
Ischaemic Stroke ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Stroke Patients ◽  
Male And Female ◽  
Cerebrovascular Risk

Introduction: To evaluate association of serum uric acid with ischemic stroke patients and assess its relationship with cerebrovascular risk factors. Methods: This was a hospital based cross-sectional observational study conducted at TUTH between May 2016 to May 2017. A total 120 Patients eligible for the study criteria was enrolled for the study. Nonprobability convenience sampling was used for the sampling purpose. All patients ages 40 years or above 40 years with confirmed diagnosis of recent ischaemic stroke were included for the analysis. Results: Mean ages of the enrolled subjects were 60.63 years ± 11.11 SD and eighty three (69.2%) population were male. Sixty one (50.8%) subjects were smoker and twenty seven (22.5%) were alcoholic. Prevalence of hyperuricemia was 17.5%. Serum uric acid level values were higher in male(69.1%) than female(30.9) population..Higher levels of serum uric acid level were found in both male population who smoked and were alcoholic in contrast serum uric acid levels were higher in both female population who were non smoker and did not consume alcohol in comparison to male. .Likewise, both diabetic and dyslipidemic male and female had higher serum uric acid level in comparison to who were non diabetic and did not consume alcohol. The mean score of serum uric acid level in male and female were significa different (P=0.029). Similalry, serum uric acid level was significantly different in smoker and no-smoker group (p=0.049), hypertensive and non hypertensive (p=0.027) and dyslipidemic and non dyslipidemic group (p=0.005) Conclusions: Our study showed high prevalence of hyperuricemia in ischemic stroke patients and there was a potential link between serum uric acid and cerebrovascular risk factors, indicating possible role of uric acid as the risk factor of ischemic stroke. Keywords: cerebrovascular risk factor; Uric acid level, recent ischaemic stroke.

A STUDY OF SERUM URIC ACID LEVELS IN PREECLAMPSIA

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sushma Goad ◽  
Anita Verma ◽  
Subhash Chandra
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Control Group ◽  
Age Group ◽  
Hypertensive Disorders Of Pregnancy ◽  
Level Elevation ◽  
The Mean

Background: To Study Serum Uric Acid level elevation in Hypertensive Disorders of Pregnancy. Methods: 50 Patients diagnosed as having Pre-eclampsia with age between 18-37 years and 50 controls with similar age group. Results: The mean serum uric acid level in control group was 3.41 ± 0.62 and in patient 7.01 ± 0.58 which was statistically significant (p =0.001). Conclusion: Serum uric acid levels were significantly higher in preeclampsia could be a useful indicator of fetal complication in preeclampsia patients. Keywords: serum uric acid, preeclampsia, laboratory.

scholarly journals Synergic effect in the reduction of serum uric acid level between ethanol extract of Aster glehni and vitamin B6

2018 ◽  
Vol 27 (5) ◽  
pp. 1439-1444 ◽  
Author(s):  
Eun Hye Han ◽  
Mi Kyung Lim ◽  
Sang Ho Lee ◽  
Hyoung Ja Kim ◽  
Dahyun Hwang
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Vitamin B6 ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Ethanol Extract ◽  
Synergic Effect

scholarly journals Lung function decline is associated with serum uric acid in Korean health screening individuals

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyung-Min Ahn ◽  
Suh-Young Lee ◽  
So-Hee Lee ◽  
Sun-Sin Kim ◽  
Heung-Woo Park
Keyword(s):  
Uric Acid ◽  
Lung Function ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Forced Expiratory Volume ◽  
Linear Regression Models ◽  
Lung Function Decline ◽  
Health Screenings

AbstractWe performed a retrospective cohort study of 19,237 individuals who underwent at least three health screenings with follow-up periods of over 5 years to find a routinely checked serum marker that predicts lung function decline. Using linear regression models to analyze associations between the rate of decline in the forced expiratory volume in 1 s (FEV1) and the level of 10 serum markers (calcium, phosphorus, uric acid, total cholesterol, total protein, total bilirubin, alkaline phosphatase, aspartate aminotransferase, creatinine, and C-reactive protein) measured at two different times (at the first and third health screenings), we found that an increased uric acid level was significantly associated with an accelerated FEV1 decline (P = 0.0014 and P = 0.037, respectively) and reduced FEV1 predicted % (P = 0.0074 and P = 8.64 × 10–7, respectively) at both visits only in non-smoking individuals. In addition, we confirmed that accelerated forced vital capacity (FVC) and FEV1/FVC ratio declines were observed in non-smoking individuals with increased serum uric acid levels using linear mixed models. The serum uric acid level thus potentially predicts an acceleration in lung function decline in a non-smoking general population.

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