scholarly journals PREVALENCE AND ANTIMICROBIAL SENSITIVITY PATTERN OF PSEUDOMONAS AERUGINOSA FROM CHRONIC SUPPURATIVE OTITIS MEDIA (CSOM) CASES IN A TERTIARY CARE HOSPITAL OF BIHAR

2017 ◽  
Vol 6 (70) ◽  
pp. 5000-5003
Author(s):  
Kumar Ajay ◽  
Kumari Namrata ◽  
Kumar Shailesh ◽  
Kumar Rakesh ◽  
Xess Anima ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

scholarly journals Evaluation of antimicrobial sensitivity pattern of chronic suppurative otitis media in a tertiary care hospital of West Bengal, India

2017 ◽  
Vol 6 (4) ◽  
pp. 891
Author(s):  
Shirsendu Mondal ◽  
Manasi Banerjee ◽  
Sudip Das
Keyword(s):  
Staphylococcus Aureus ◽  
Otitis Media ◽  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

Background: Chronic suppurative otitis media is a common infectious disease in our country. The micro-organisms commonly causing the disease and their antibiotic sensitivity pattern is important for treatment. This study was conducted to evaluate the antimicrobial sensitivity pattern of the common microorganisms in patients with chronic suppurative otitis media in our tertiary care hospital.Methods: The study was carried out from July 2013 to December 2013 at the ENT out-patient department of a tertiary care hospital in West Bengal. 100 patients aged 18 to 60 years of either sex, with unilateral or bilateral active chronic suppurative otitis media attending the out- patient clinic were included in the study. Pus samples were collected from the discharging ears and sent for isolating the organisms and susceptibility testing.Results: A total number of 108 ear swabs were collected from the 100 recruited patients of which 15 (13.88%) were sterile and 93 (86.11%) showed presence of organisms. Pseudomonas aeruginosa 41(38%) was the commonest organism isolated, followed by Staphylococcus aureus 25(23.15%). The antimicrobial profile of the microorganisms reveals maximum sensitivity of the isolated organisms to piperacillin and levofloxacin.Conclusions: In our study, Pseudomonas aeruginosa (38%) and Staphylococcus aureus (23.15%) are the major pathogens involved in the etiology of CSOM. The isolates showed maximum sensitivity to piperacillin (41%) and levofloxacin (41%). As piperacillin is available only in parenteral form and is also costly, topical levofloxacin can be recommended in empirical treatment of CSOM.

scholarly journals Therapeutic guidelines for antimicrobial use in chronic suppurative otitis media for a tertiary care hospital in Sub Himalayan region

2018 ◽  
Vol 7 (3) ◽  
pp. 416
Author(s):  
Sushma Sawaraj ◽  
Sunder Singh Dogra ◽  
Dinesh Kansal ◽  
Kamlesh Thakur ◽  
Parveen Kumar Sharma
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Antimicrobial Therapy ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern

Background: The battle against micro-organisms, in their role as primary cause of the disease and infective complications of medical and surgical techniques, has not decreased in spite of modern antimicrobial therapy. Chronic suppurative otitis media (CSOM) is a disease with worldwide prevalence having potentially serious long term effects. The disease remains an important global public health problem leading to hearing impairment, and due to wide spread irrational use microbial resistance is very common to these antibiotics, thereby leading to treatment failure. Hence it is important to know the type of bacteria and their sensitivity pattern so that appropriate antibiotics may be given for treatment and prevention of complications.Methods: 428 patients of otitis media were enrolled from ENT OPD of Tertiary Care Hospital. Ear swab was taken from diagnosed cases of CSOM and culture and sensitivity were done.Results: The microbiology of the swab showed no growth in (25.4%) of samples. Staphylococcus aureus (26%) and Pseudomonas (25%) were the main organisms isolated. Staphylococcus aureus isolated was sensitive to vancomycin, clindamycin, cefixime, gentamicin and cefipime in descending order. Pseudomonas aeruginosa was sensitive to ceftazidime, imipenem, piperacillin, gentamicin, cefipime. In the present study Staph. aureus and Pseudomonas were the predominant bacteria, it is suggested to undertake a gram staining in all patients. If gram positive organisms are isolated it is suggested that presumptive treatment should be directed against Staphylococcus aureus and if gram negative then against Pseudomonas aeruginosa. Such a treatment is not only likely to be effective but will also go a long way in preventing emergence of drug resistance.Conclusions: The antimicrobial therapy should be based on locally determined microbiological isolates and local sensitivity patterns to a particular antimicrobial agent. The presumptive antimicrobial therapy should therefore be directed against these organisms.

scholarly journals Aerobic bacteriology of Chronic Suppurative Otitis Media (CSOM) in a tertiary care hospital: A retrospective study

2012 ◽  
Vol 7 (2) ◽  
pp. 1-8 ◽  
Author(s):  
RK Sanjana ◽  
YI Singh ◽  
NS Reddy
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
National Committee ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Sensitivity Pattern

The present study was carried out to determine the aerobic microorganisms involved and their antibiotic sensitivity pattern in patients with Chronic Suppurative Otitis Media (CSOM) and to provide a guideline for empirical antibiotic therapy.Between March 2009 to February 2011, the ear discharge samples submitted at the microbiology laboratory were processed aerobically and all the isolates were included in this study. All organisms were identified morphologically and biochemically by standard laboratory procedures and antibiotic susceptibility pattern was determined by modified Kirby Bauer disc diffusion method as per National Committee for Clinical Laboratory Standard recommendations.Out of a total of 214 samples, microbiological culture was yielded from 202 (94.3%) specimens. Single organism were isolated from 168 (78.5%) of the culture positive specimens, while the remaining 34 (15.9%) had two or more organisms isolated. Pseudomonas aeruginosa 59 (35.1%) was the most common isolate, followed by Staphylococcus aureus 42 (25.0%) including 5 (3%) of the Methicillin Resistant Staphylococcus Aureus (MRSA). Antibiotic sensitivities of Pseudomonas aeruginosa showed that 93.2% isolates were sensitive to tobramycin, whereas, 91.5% isolates were sensitive to ceftazidime and 77.9% to amikacin.Only 50.8% of the isolates of Pseudomonas aeruginosa were sensitive to ciprofloxacin and 25.4% to gentamicin. For Staphylococcus aureus (other than MRSA) 95.2% were sensitive to cloxacillin, 83.3% to gentamicin and 78.5% to erythromycin. Only 07.1% were sensitive to ampicillin and 26.1% to ciprofloxacin.Pseudomonas aeruginosa was the most common isolate followed by Staphylococcus aureus. More than 90% of Pseudomonas and 90% of Staph aureus were sensitive to tobramycin and cloxacillin respectively. Therefore, these two drugs may be included in the formulary to cover the most common aerobic isolates involved in CSOM.Journal of College of Medical Sciences-Nepal, 2011, Vol-7, No-2, 1-8DOI: http://dx.doi.org/10.3126/jcmsn.v7i2.6673

scholarly journals A study of microbial gamut and antibiograms in chronic suppurative otitis media

2018 ◽  
Vol 5 (1) ◽  
pp. 110
Author(s):  
Raj Tajamul Hussain ◽  
Sanam Altaf ◽  
Owais Makhdoomi ◽  
Mariya Ali
Keyword(s):  
Otitis Media ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Chronic Suppurative Otitis Media ◽  
Fungal Culture ◽  
Care Hospital ◽  
Biochemical Tests ◽  
Suppurative Otitis Media ◽  
Gram Staining ◽  
Sensitivity Pattern

<p class="abstract"><strong>Background:</strong> The aim of the study was to discern the patterns in microbial diversity and the resistogram among the patients suffering from CSOM.</p><p class="abstract"><strong>Methods:</strong> A total number of 100 ear swabs were investigated for the present study. Their gram staining, direct microscopy with KOH, culture sensitivity, and biochemical tests were carried out to identify the organisms and to know their sensitivity pattern. All the swabs were collected from clinically diagnosed cases of chronic suppurative otitis media visiting otolaryngology outpatient department of tertiary care hospital. The study period was one year, from January 2016 to December 2017.  </p><p class="abstract"><strong>Results:</strong> Out of total 100 cases, 90 were culture<strong> </strong>positives, 6 showed no growth and 4 were<strong> </strong>skin contaminants (mirococci). Out of 90 culture positives, fungal culture was positive in 5 (5.5%) while combined bacteria and fungi obtained in 18 (20%) cases and only bacteria in 67 (74.4%) cases. Among the aerobic bacterial isolates, Pseudomonas aeruginosa was the most common bacteria isolated from the bacterial culture (n=36; 34.95%) followed by <em>Staphylococcus aureus </em>(n=28; 27.18%) and <em>Proteus</em> (n=13; 12.62%). Among the fungal isolates,<strong> </strong><em>Aspergillus niger </em>was predominant followed<strong> </strong>by Candida <em>albicans </em>&amp; <em>Aspergillus flavus.</em> Amikacin and imipenem were found to be the most effective antibiotics with low resistance rates.</p><p><strong>Conclusions:</strong> The present study gave an insight into the bacteriological profile of the cases of CSOM and their antibiotic sensitivity patterns. This in turn will ensure rational and judicious use of antibiotics and thus prevent emergence of resistant bugs and also the complications associated with CSOM.</p>

scholarly journals Microbiology of Chronic Suppurative Otitis Media: An update from a Tertiary Care Hospital in Bangladesh

2021 ◽  
Vol 37 (3) ◽  
Author(s):  
Mst. Romena Khatun ◽  
Kh. Md. Faisal Alam ◽  
Mahmuda Naznin ◽  
Md. Abdus Salam
Keyword(s):  
Otitis Media ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Gram Negative ◽  
Medical College ◽  
Gram Positive Bacteria ◽  
Amoxicillin Clavulanate

Objectives: Chronic suppurative otitis media is a major cause of acquired hearing impairment, especially in children of developing countries. The study sought to explore the bacteriological profile and their antimicrobial susceptibility among patients of chronic suppurative otitis media from a tertiary care hospital in Bangladesh. Methods: A cross sectional microbiological study was conducted at the Department of Microbiology, Rajshahi Medical College, Bangladesh from January to December 2019. Aural swabs were collected aseptically from clinically suspected patients irrespective of age and gender attending the ear, nose and throat outpatient department of Rajshahi Medical College Hospital. Aerobic bacterial culture was done and isolates were identified through standard bacteriological identification scheme. Antimicrobial susceptibility testing of isolates was done by modified Kirby-Bauer disk diffusion method following Clinical and Laboratory Standards Institute guidelines. Results: Of 96 swabs, culture yielded a total of 73 bacterial isolates from 68(70.8%) culture-positive plates including 63 (65.6%) unimicrobial and 5 (5.2%) polymicrobial (mixed growth of a pair of bacteria) growths. Frequency distribution revealed, 40(55%) gram-negative and 33(45%) gram-positive bacteria with Staphylococcus aureus was the leading isolate (37%) followed by Pseudomonas aeruginosa (31.5%), Escherichia coli (13.7%), coagulase-negative Staphylococcus (8.2%), Klebsiella pneumoniae (5.5%) and Proteus spp. (4.1%). Gram-positive bacteria were found to be highly susceptible (100%) to Linezolid and Vancomycin followed by Imipenem (83 to 96.3%), while moderate to high resistance (44 to 67%) was observed against Ciprofloxacin, Ceftriaxone, Ceftazidime, Amoxicillin/Clavulanate and Clindamycin. For gram-negative bacteria, susceptibility ranged from 67 to 100% to Imipenem, 67 to 96% to Piperacillin/Tazobactam and 67 to 83% to Gentamicin, while moderate to high resistance (50 to 75%) was observed against Ciprofloxacin, Ceftriaxone, Ceftazidime and Amoxicillin/Clavulanate. Conclusion: Moderate to high level of multidrug-resistance especially to 3rd generation cephalosporins, Ciprofloxacin and Amoxicillin/Clavulanate is an alarming situation. It warns reinforcement of judicious antibiotic prescription and introduction of antibiotic stewardship program in the tertiary care hospitals. doi: https://doi.org/10.12669/pjms.37.3.3942 How to cite this:Khatun MR, Alam KMF, Naznin M, Salam MA. Microbiology of Chronic Suppurative Otitis Media: An update from a Tertiary Care Hospital in Bangladesh. Pak J Med Sci. 2021;37(3):---------. doi: https://doi.org/10.12669/pjms.37.3.3942 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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