scholarly journals STUDY OF HIGH SPECIFIC C-REACTIVE PROTEIN IN ACUTE ISCHAEMIC STROKE

2019 ◽  
Vol 8 (15) ◽  
pp. 1243-1247
Author(s):  
Madhan Kumar Subbarayan ◽  
Chinnaiyan P ◽  
Sravankumar Sampati
2014 ◽  
Vol 30 (1) ◽  
pp. 45-49
Author(s):  
Kazi Giasuddin Ahmed ◽  
Abu Saleh Md Badrul Hasan ◽  
Biplop Kumar Roy ◽  
Md Rafiqul Islam ◽  
Md Ruhul Quddus

Background: Stroke is a dreadful health hazard all over the world as well as in our country. The relationship between serum C-reactive protein (CRP) level and acute ischaemic stroke is not well studied especially in Bangladesh. Aims and Objectives: To evaluate the association of C-reactive protein (CRP) in acute ischemic stroke .Materials and Methods: This case-control study was carried out in the Department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period from January 2006 to December 2007. A total of 30 acute ischaemic stroke patients were included in the case group. Another 30 age and sex matched and apparently healthy persons without any stroke were taken as controls. Results: The stroke patients [21 (70.0%) male; mean age, 56.3 (SD±13.7) years] and control subjects [25 (83.3%) male; mean age, 53.4 (SD ± 9.9) years] were similar in age and sex (p>0.05 each). CRP level was significantly higher in acute ischaemic stroke patients than that of control [42.06 (SD ± 21.26) mg/L; vs 4.30 (SD ± 0.072) mg/L; p<0.001]. CRP was found positive in 28 (93.7%) stroke patients and none of the control subjects. CRP was 16 times significantly higher in stroke patients than that of control subjects (OR=16.00; 95% CI=4.18-61.22; p<0.001).Conclusion: This study confirms that CRP is elevated in acute ischaemic stroke. More local studies are required regarding the significance of CRP as a risk factor for acute ischemic stroke. Bangladesh Journal of Neuroscience 2014; Vol. 30 (1): 45-49


Biomarkers ◽  
2020 ◽  
Vol 25 (7) ◽  
pp. 525-532
Author(s):  
Ziyi Hu ◽  
Junyu Lai ◽  
Lisha Chen ◽  
Ying Yi ◽  
Renliang Li ◽  
...  

2015 ◽  
pp. 1743132815Y.000 ◽  
Author(s):  
Jichen Du ◽  
Dan Yu ◽  
Xiaofeng Li ◽  
Zhongyun Chen ◽  
Jing Li ◽  
...  

2002 ◽  
Vol 30 (6) ◽  
pp. 591-596 ◽  
Author(s):  
İ İyigün ◽  
Y Bakirci

This study investigated how fibrinogen and C-reactive protein (CRP) levels change in response to neural damage occurring after ischaemia, and the relationship between the distribution of the arterial lesion, the disease prognosis and the levels of these substances. Fibrinogen and CRP levels were measured in blood samples obtained from 83 patients admitted to hospital within 72 h of a first ischaemic stroke. The patients were evaluated clinically with the Glasgow Outcome Scale (GOS), and results were compared with 43 age-matched controls. The fibrinogen and CRP levels in unconscious patients with hemiparesis or hemiplegia were higher than those in conscious hemiplegic patients. Also, the difference in GOS values between the unconscious patients with hemiparesis or hemiplegia and conscious patients with hemiparesis or hemiplegia was statistically significant. Patients with large infarcts in the median cerebral artery and anterior cerebral artery had higher fibrinogen and CRP concentrations than the control group. In conclusion, fibrinogen and CRP may be important measures for determining the prognosis and outcome in patients following ischaemic stroke.


Sign in / Sign up

Export Citation Format

Share Document