scholarly journals Estimation of blood antimicrobial peptide levels in women of reproductive age with pelvic inflammatory disease before and after antibiotic therapy

2021 ◽  
Vol 16 (2) ◽  
Author(s):  
Vladimir Baturin ◽  
Roberta Boshyan
Keyword(s):  
Antibiotic Therapy ◽  
Antimicrobial Peptide ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Before And After

scholarly journals Laparoscopic evaluation of female infertility in low socioeconomic status

2018 ◽  
Vol 7 (8) ◽  
pp. 3232
Author(s):  
Chesta Saini ◽  
Ashoo Gupta ◽  
Kishore Rajurkar ◽  
Kartik Saxena ◽  
Kanchan Saini ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Low Socioeconomic Status ◽  
Inflammatory Disease ◽  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Low Socioeconomic ◽  
Infertile Women ◽  
Major Factors ◽  
Reproductive Age Group

Background: Infertility is a multidimensional health issue which is rising dramatically. The common causes include ovarian, uterine, tubal disorders, hormonal imbalance, age-related factors and lifestyle factors. The low economic strata poses a subset of problems like difficulty in seeking healthcare, treatment costs and poor compliance. Authors sought to evaluate the factors for primary and secondary infertility in women of reproductive age group who belong to low socio-economic strata using laparoscopy.Methods: A prospective observational study was conducted in the obstetrics and gynaecology department at Sanjay Gandhi memorial hospital, Delhi comprising 50 infertile women of reproductive age group belonging to low socioeconomic class for a period of 2 years from June 2015 onwards.Results: Among primary infertility, tuberculosis (27.02%), ovarian cyst (16.22%), adhesions (10.81%), polycystic ovaries (10.81%) and Pelvic inflammatory disease (10.81%) were the major findings whereas in secondary infertility Pelvic inflammatory disease (23.07%), tuberculosis (15.38%), adhesions (15.38%) and endometriosis (7.69%) were the major factors seen in the study.Conclusions: Tuberculosis and pelvic inflammatory disease were the major factors seen in infertile women of low socioeconomic status thus, they should be kept high on the list of differential diagnosis even if the investigative work up is negative.

scholarly journals Clinical pathogenic basis for anti-adhesive treatment for appendicular-genital syndrome in women of reproductive age

2020 ◽  
Vol 3 (4) ◽  
pp. 228-232
Author(s):  
V.V. Simrok ◽  
◽  
I.A. Popova ◽  
D.V. Mel’nikova ◽  
◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Clinical Symptoms ◽  
Adhesion Formation ◽  
Fold Increase ◽  
Reproductive Age ◽  
Complex Treatment ◽  
Women Of Reproductive Age ◽  
Peritoneal Adhesions ◽  
Normal Ranges

Aim: to assess the efficacy of penicillamine for the complex prevention of pelvic peritoneal adhesions in appendicitis associated with the acute conditions of uterine appendages (appendicular-genital syndrome, AGS) based on the changes in the levels of hydroxyproline and the major clinical symptoms of pelvic inflammatory disease. Patients and Methods: 157 women of reproductive age with AGS who were urgently or routinely admitted to a gynecological or surgical hospital were examined. Comparison group women were prescribed with conventional anti-inflammatory treatment or surgery as needed. Study group women additionally received penicillamine 250 mg twice daily for a month. Pre- and post-treatment non-invasive assessment of the peritoneal adhesive process was performed by measuring the levels of protein-bound and free hydroxyproline. Treatment efficacy was evaluated after 1 month by the changes in hydroxyproline levels, major clinical symptoms, and ultrasound. Results: it was demonstrated that pelvic acute inflammatory disease results in > 1.5-fold increase in the levels of protein-bound and free hydroxyproline. Penicillamine as a component of the complex treatment for pelvic inflammatory disease reduces the levels of hydroxyproline to normal ranges. The changes in the major clinical symptoms and ultrasonic findings after penicillamine therapy were more significant compared to the standard treatment. Conclusions: penicillamine as a component of the complex treatment for pelvic inflammatory disease significantly accelerates the improvement of symptoms and remission as well as the formation of peritoneal adhesions. This prevents both pelvic adhesive disease and tubal- and peritoneal-factor infertility. KEYWORDS: appendicular-genital syndrome, inflammation, hydroxyproline, penicillamine, pelvic peritoneal adhesions, prevention, adhesion formation. FOR CITATION: Simrok V.V., Popova I.A., Mel’nikova D.V. Clinical pathogenic basis for anti-adhesive treatment for appendicular-genital syndrome in women of reproductive age. Russian Journal of Woman and Child Health. 2020;3(4):228–232. DOI: 10.32364/2618-8430- 2020-3-4-228-232.

Pelvic Inflammatory Disease

2009 ◽  
Vol 2 (9) ◽  
pp. 517-521
Author(s):  
Alexander Hodson
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Female Genital Tract ◽  
Reproductive Age ◽  
Common Condition ◽  
Women Of Reproductive Age ◽  
Infection And Inflammation ◽  
Female Genital

Pelvic inflammatory disease (PID), infection and inflammation of the upper female genital tract, is a common condition managed by General Practitioners (GPs). It accounts for one in 60 consultations in women of reproductive age. Early diagnosis, management and, if necessary, referral is essential to help prevent serious long-term complications such as ectopic pregnancy, infertility and chronic pelvic pain. This article outlines the causes, clinical features, treatment and follow-up of PID.

scholarly journals Ureaplasma spp and mycoplasma hominis in women of reproductive age with pelvic inflammatory disease

2019 ◽  
Vol 61 (1) ◽  
pp. 1
Author(s):  
Dina Nuradilova ◽  
Lira Kaliyeva ◽  
Daiva Vaitkiene ◽  
Saltanat Kalimoldayeva ◽  
Khasen Dasibekov ◽  
...  
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Mycoplasma Hominis ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ureaplasma Spp

scholarly journals Mesenchymal Stem Cells in Restoration of Fertility at Experimental Pelvic Inflammatory Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Nataliia Volkova ◽  
Mariia Yukhta ◽  
Anatoliy Goltsev
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Relative Number ◽  
Reproductive Age ◽  
Control Group ◽  
Women Of Reproductive Age ◽  
Stimulation Of ◽  
Restoration Of Fertility

Inflammatory disorders account for a significant percentage of gynecologic diseases, particularly in women of reproductive age. It is known that stem cells have anti-inflammatory and regenerative properties. Based on this, we investigated the effect of intravenous administration of cryopreserved mesenchymal stem cells (cMSCs) of bone marrow on experimental chronic inflammation of the ovaries. The paper shows that on the 21st day after cMSC therapy, leukocyte infiltration of ovaries was slightly relative to the control group without treatment, and the ratio of developing and atretic follicles in the animals with cMSC injection dramatically increased, while in the control, it still remained on the side of atretic forms. The number of apoptotic oocytes after stimulation of superovulation in the control group was significantly higher (85.3 ± 5.2%) than that in the animals with therapy (5.7 ± 0.8%). Relative number of fertilized eggs in the group with cMSC therapy was higher by 40% compare to that in the control. Pregnancy rate in natural estrous cycle after cell administration increased by 20%, and average number of litters in this group was two times significantly higher than that in the control. So the intravenous injection of cMSCs has the restorative effect on the fertility at experimental pelvic inflammatory disease.

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