Deep vein thrombosis incidence in women diagnosed with breast cancer in brazil between 2007-2009

This case report describes the delayed diagnosis of inflammatory breast cancer following initial presentation with a subclavian/axillary deep vein thrombus. The relationship of thrombosis and cancer is discussed and the typical presentation of inflammatory breast cancer described. Understanding the relationship between thromboembolism and cancer is crucial to support the early diagnosis of breast cancer, which can present insidiously. The literature is reviewed, highlighting the improving prognosis of this rare condition and the current preferred treatment modalities.

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Risk of Cardiovascular Diseases Among Older Breast Cancer Survivors in the United States: A Matched Cohort Study

Journal of the National Comprehensive Cancer Network ◽

10.6004/jnccn.2020.7629 ◽

2021 ◽

Vol 19 (3) ◽

pp. 275-284

Author(s):

Anthony A. Matthews ◽

Sharon Peacock Hinton ◽

Susannah Stanway ◽

Alexander R. Lyon ◽

Liam Smeeth ◽

...

Keyword(s):

Breast Cancer ◽

Heart Failure ◽

Deep Vein Thrombosis ◽

Cancer Survivors ◽

Breast Cancer Survivors ◽

The United States ◽

Cardiovascular Outcomes ◽

Vein Thrombosis ◽

Deep Vein

Background: It has been suggested that cardiovascular risks are increased in breast cancer survivors, but few studies have quantified the risks of a range of specific clinically important cardiovascular outcomes in detail. Patients and Methods: Women aged >65 years with incident breast cancer from 2004 to 2013 in the SEER-Medicare linked database were matched with 5 cancer-free female counterparts (5:1 ratio). Prevalence of specific cardiovascular outcomes at baseline was measured, then Cox regression was used to calculate hazard ratios (HRs) and 95% confidence intervals for the risk of individual cardiovascular outcomes during follow-up. Modification of the effect was investigated by time since diagnosis, race/ethnicity, prior cardiovascular disease (CVD), and age. Results: In all, 91,473 women with breast cancer and 454,197 without breast cancer were included. Women with breast cancer had lower baseline prevalence of all CVDs. Compared with cancer-free controls, breast cancer survivors had substantially increased risks of deep vein thrombosis (adjusted HR, 1.67; 95% CI, 1.62–1.73; 386,484 person-years of follow-up) and pericarditis (HR, 1.43; 95% CI, 1.38–1.49; 390,776 person-years of follow-up); evidence of smaller increased risks of sudden cardiac arrest, arrhythmia, heart failure, and valvular heart disease (adjusted HRs ranging from 1.05–1.09, lower CI limits all ≥1); and evidence of lower risk of incident angina, myocardial infarction, revascularization, peripheral vascular disease, and stroke (adjusted HRs ranging from 0.89–0.98, upper CI limits all ≤1). Increased risks of arrhythmia, heart failure, pericarditis, and deep vein thrombosis persisted >5 years after cancer diagnosis. Conclusions: Women with a history of breast cancer were at increased risk of several CVDs, persisting into survivorship. Monitoring and managing cardiovascular risk throughout the long-term follow-up of women diagnosed with breast cancer should be a priority.

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Factor V Leiden Mutation in Patients with Breast Cancer with a Central Venous Catheter: Risk of Deep Vein Thrombosis

Supportive Cancer Therapy ◽

10.3816/sct.2006.n.005 ◽

2006 ◽

Vol 3 (2) ◽

pp. 98-102 ◽

Cited By ~ 8

Author(s):

Giuseppe Curigliano ◽

Mario Mandalà ◽

Alberto Sbanotto ◽

Marco Colleoni ◽

Gianluigi Ferretti ◽

...

Keyword(s):

Breast Cancer ◽

Deep Vein Thrombosis ◽

Central Venous Catheter ◽

Factor V Leiden ◽

Venous Catheter ◽

Factor V ◽

Central Venous ◽

Factor V Leiden Mutation ◽

Vein Thrombosis ◽

Deep Vein

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Factor V Leiden mutation in patients with breast cancer and a central venous catheter: Relationship with deep vein thrombosis

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.8020 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 8020-8020 ◽

Cited By ~ 1

Author(s):

G. Curigliano ◽

M. Mandalà ◽

P. Bucciarelli ◽

G. Peruzzotti ◽

M. Colleoni ◽

...

Keyword(s):

Breast Cancer ◽

Deep Vein Thrombosis ◽

Central Venous Catheter ◽

Factor V Leiden ◽

Venous Catheter ◽

Factor V ◽

Central Venous ◽

Factor V Leiden Mutation ◽

Vein Thrombosis ◽

Deep Vein

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Upper-Extremity Deep Vein Thrombosis in Patients With Breast Cancer With Chest Versus Arm Central Venous Port Catheters

Breast Cancer Basic and Clinical Research ◽

10.1177/1178223418771909 ◽

2018 ◽

Vol 12 ◽

pp. 117822341877190 ◽

Cited By ~ 2

Author(s):

Danielle Tippit ◽

Eric Siegel ◽

Daniella Ochoa ◽

Angela Pennisi ◽

Erica Hill ◽

...

Keyword(s):

Breast Cancer ◽

Deep Vein Thrombosis ◽

Upper Extremity ◽

Venous Access ◽

High Risk Population ◽

Safe Delivery ◽

Vein Thrombosis ◽

Venous Access Device ◽

Deep Vein ◽

Active Cancer

Most of the patients undergoing treatment for cancer require placement of a totally implantable venous access device to facilitate safe delivery of chemotherapy. However, implantable ports also increase the risk of deep vein thrombosis and related complications in this high-risk population. The objective of this study was to assess the incidence of upper-extremity deep vein thrombosis (UEDVT) in patients with breast cancer to determine whether the risk of UEDVT was higher with chest versus arm ports, as well as to determine the importance of previously reported risk factors predisposing to UEDVT in the setting of active cancer. We retrospectively reviewed the medical records of 297 women with breast cancer who had ports placed in our institution between the dates of December 1, 2010, and December 31, 2016. The primary outcome was the development of radiologically confirmed UEDVT ipsilateral to the implanted port. Overall, 17 of 297 study subjects (5.7%) were found to have UEDVT. There was 1 documented case of associated pulmonary embolism. Fourteen (9.5%) of 147 subjects with arm ports experienced UEDVT compared with only 3 (2.0%) of 150 subjects with chest ports ( P = .0056). Thus, implantation of arm ports as opposed to chest ports may be associated with a higher rate of UEDVT in patients with breast cancer.

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