Gender Disparities in Short-Term and Long-Term Colon Cancer Specific Survival

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S98-S99
Author(s):  
Venu Gopala Reddy Gangireddy ◽  
Swathi Talla
Keyword(s):  
Colon Cancer ◽  
Gender Disparities ◽  
Short Term ◽  
Cancer Specific Survival

scholarly journals Short‐term and long‐term outcomes of laparoscopic colectomy with multivisceral resection for surgical T4b colon cancer: Comparison with open colectomy

2020 ◽  
Vol 4 (6) ◽  
pp. 676-683 ◽  
Author(s):  
Masaaki Miyo ◽  
Takeshi Kato ◽  
Yusuke Takahashi ◽  
Masakazu Miyake ◽  
Reishi Toshiyama ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Laparoscopic Colectomy ◽  
Multivisceral Resection ◽  
Open Colectomy ◽  
Long Term Outcomes ◽  
Short Term

Short-Term and Long-Term Outcomes of Self-Expanding Metallic Stent Versus Decompressing Stoma as the Bridge of Elective Surgery for Left-Sided Obstructive Colon Cancer A Meta-Analysis

2021 ◽  
Vol 7 (5) ◽  
pp. 1853-1864
Author(s):  
Jin Jing ◽  
Wei Xu ◽  
Haiming Xu ◽  
ZhengHong Yu ◽  
Mengyun zhou ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Elective Surgery ◽  
Meta Analysis ◽  
Complete Analysis ◽  
Cochrane Library ◽  
Metallic Stent ◽  
Sems Placement ◽  
Short Term ◽  
Significant Difference

Background: Compared to emergency resection, elective surgery is a better choice for the people suffering from left-sided obstructive colon cancer (LOSCC). Both are considered as self-expanding decompressing stoma (DS) construction and metallic stent (SEMS) placement are accessible bridges for elective surgery (BTS). We aimed to perform meta-analysis of LOSCC databases to comparethe pros and cons of the two options. Method: LOSCC patients with curative intent were searched in medical databases, including PUBMED, MEDLINE, and the Cochrane Library. Results were expressed as risk ratios. The meta-analysis was performed by Revman5.3. Result: Three comparative studies were selected, including 847 LOSCC patients. The complete analysis showed that there is no statistically significant difference regarding primary anastomosis (0R=1.15, 95% CI 0.30-4.41, P=0.84), There was no significant difference in 90-day recurrence rate post resection (OR=0.90, 95% CI 0.68-1.20, P=0.47), and major complication (OR=1.86, 95% CI 0.98-3.54, P=0.06) between SEMS and DS group. In addition, the permanent stomas (OR=0.82; 95% CI 0.60-1.13, P=0.23), overall recurrence (OR=0.82, 95% CI 0.48-1.40, P=0.46), and overall survival of 3-years (OR=1.24, 95% CI 0.69-2.25, P=0.48) showed no statistical difference between SEMS and DS group. Conclusion: The after-effects of both short-term and long-term in patients who were treated by SEMS or DS as BTS for LSOCC were not statistically significant. Considering of the even complicated surgical interventions, prolonged hospital stays, and worse body image of DS construction, SEMS placement seems to be the preferred option in treating LSOCC patients.

Comparative analysis of second and subsequent chemotherapy lines on short- and long-term survival of elderly Medicare metastatic colon cancer patients.

2013 ◽  
Vol 31 (4_suppl) ◽  
pp. 455-455
Author(s):  
Nader Hanna ◽  
Ebere Onukwugha ◽  
Kaloyan A Bikov ◽  
Zhiyuan Zheng ◽  
Brian S. Seal ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Comparative Analysis ◽  
Metastatic Colon Cancer ◽  
Short Term ◽  
Term Survival ◽  
Long Term Survival ◽  
Line Therapy ◽  
Short And Long Term ◽  
Diagnosis Date

455 Background: Metastatic colon cancer (mCC) patients often receive multiple lines of chemotherapy as treatment (TX) to improve survival or quality of life, yet the “real world” benefits and risks of multiple TX lines have not been fully examined. Methods: Elderly (65+) SEER-Medicare patients diagnosed with mCC in 2003-2007 were followed until death or 12/31/09 to examine the survival benefits for different chemotherapy lines. The median time between diagnosis date and the starting date of 2nd line was 352 days. Therefore, we restricted comparative analysis of 2nd and subsequent chemotherapy TX lines to patients who survived at least 1 year after mCC diagnosis date. We used Cox regression framework and adjusted for patients’ TX and censoring histories by using inverse probability weighting method. Separate analyses were conducted for short (2 years) and long-term (5 years) survival to examine different benefits of 2nd and subsequent chemotherapy lines. Results: Of 2,600 elderly Medicare mCC patients diagnosed between 2003-2007 and who survived at least 1 year, 2,530 were dead by the end of 2009. Significant factors associated with long-term survival were 1st line therapy(HR = 0.76; p < 0.01), 2nd line therapy (HR = 0.83; p < 0.01) , and subsequent chemotherapy line therapy(HR = 0.85; p = 0.04), as compared to no therapy, age groups 95+ (HR = 3.07; p < 0.01), 85-94 (HR = 1.33; p < 0.01), and 75-84 (HR = 1.10; p = 0.04) as compared to 65+-74, Asian vs. White (HR = 0.71; p < 0.01), and zip code level household median income (HR = 0.98; p = 0.01). For short-term survival, the benefits of 2nd and subsequent chemotherapy lines were maintained until month 29. Patients with poor performance status were less likely to proceed to 2nd line therapy. No statistically significant variables predicting receipt of subsequent chemotherapy lines were identified. Conclusions: Among elderly Medicare mCC patients who survived at least 1 year after diagnosis, 1st line therapy improved both short and long-term survival. 2nd and subsequent chemotherapy line therapy reduced short-term mortality (2 years); however, they didn’t add any additional long term survival benefit (5 years) as compared to 1st line therapy.

Association Between the Most Frequent Complications After Surgery for Stage I–III Colon Cancer and Short-Term Survival, Long-Term Survival, and Recurrences

2016 ◽  
Vol 23 (9) ◽  
pp. 2858-2865 ◽  
Author(s):  
A. J. Breugom ◽  
D. T. van Dongen ◽  
E. Bastiaannet ◽  
F. W. Dekker ◽  
L. G. M. van der Geest ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Stage I ◽  
Short Term ◽  
Term Survival ◽  
Long Term Survival ◽  
Short Term Survival

scholarly journals Long-Term Outcomes of Colon Cancer Patients Undergoing Standardized Technique Operation With Curative Intent

2015 ◽  
Vol 100 (11-12) ◽  
pp. 1382-1395
Author(s):  
Erhan Akgun ◽  
Cemil Caliskan ◽  
Tayfun Yoldas ◽  
Can Karaca ◽  
Bulent Karabulut ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Patients ◽  
Cox Regression ◽  
Disease Free Survival ◽  
Disease Recurrence ◽  
R0 Resection ◽  
Cancer Specific Survival ◽  
Curative Intent ◽  
Lymph Node Count

There is no defined standard surgical technique accepted worldwide for colon cancer, especially on the extent of resection and lymphadenectomy, resulting in technical variations among surgeons. Nearly all analyses employ more than one surgeon, thus giving heterogeneous results on surgical treatment. This study aims to evaluate long-term follow-up results of colon cancer patients who were operated on by a single senior colorectal surgeon using a standardized technique with curative intent, and to compare these results with the literature. A total of 269 consecutive patients who were operated on with standardized technique between January 2003 and June 2013 were enrolled in this study. Standardized technique means separation of the mesocolic fascia from the parietal plane with sharp dissection and ligation of the supplying vessels closely to their roots. Patients were assessed in terms of postoperative morbidity, mortality, disease recurrence, and survival. Operations were carried out with a 99.3% R0 resection rate and mean lymph node count of 17.7 nodes per patient. Surviving patients were followed up for a mean period of 57.8 months, and a total of 19.7% disease recurrence was recorded. Mean survival was 113.9 months. The 5- and 10-year survival rates were 78% and 75.8% for disease-free survival, 82.6% and 72.9% for overall survival, and 87.5% and 82.9% for cancer-specific survival, respectively. R1 resection and pathologic characteristics of the tumor were found to be the most important prognostic factors according to univariate and Cox regression analyses. Standardization of surgical therapy and a dedicated team are thought to make significant contributions to the improvement of prognosis.

Sign in / Sign up

Export Citation Format

Share Document