scholarly journals Modern concepts for the diagnosis and treatment of hypothyroidism in adults

2004 ◽  
Vol 50 (2) ◽  
pp. 47-53
Author(s):  
V. V. Fadeev
Keyword(s):  
Clinical Practice ◽  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Subclinical Hypothyroidism ◽  
Endocrine System ◽  
Epidemiological Studies ◽  
Diagnosis And Treatment ◽  
Population Groups ◽  
Common Diseases

The relevance of the problem of hypothyroidism in the clinical practice of doctors of all specialties is not necessary. Hypothyroidism is one of the most common diseases of the endocrine system. According to some epidemiological studies, in certain population groups the prevalence of subclinical hypothyroidism reaches 10-12% [16]. In the last decade, a large number of works on the problem of hypothyroidism have appeared, which have transformed our views on the entire pathology of the thyroid gland (thyroid gland). This is primarily due to the introduction of modern thyroid hormone preparations into clinical practice.

scholarly journals Hypothyroidism - A New View On An Old Disease

KYAMC Journal ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. 707-713 ◽  
Author(s):  
Md Imtiajul Islam ◽  
Md Zulfikar Ali ◽  
Md Saiful Islam ◽  
Mohammed Solayman ◽  
Sayama Hoque
Keyword(s):  
Differential Diagnosis ◽  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Older Persons ◽  
Autoimmune Thyroid Disease ◽  
Clinical Symptoms ◽  
Endocrine System ◽  
Autoimmune Thyroid ◽  
Laboratory Examinations ◽  
Obesity Hypertension

Hypothyroidism is a common disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone. Underactivity of thyroid is usually primary, from disease of thyroid, but may be secondary to hypothalamic-pituitary disease (reduced TSH drive). Untreated hypothyroidism can cause a number of health problems, such as obesity, hypertension, dyslipidaemia, infertility. The prevalence increases with age, and is higher in females than in males. Autoimmune thyroid disease is the most common aetiology of hypothyroidism. Clinical symptoms of hypothyroidism are nonspecific and may be subtle, especially in older persons. TSH and FT4 measurement are the laboratory examinations necessary for the diagnosis of hypothyroidism as well as the differential diagnosis between primary (clinical or subclinical) and secondary one. In the majority of patients, alleviation of symptoms can be accomplished through oral administration of synthetic levothyroxine, and most patients will require lifelong therapy.KYAMC Journal Vol. 7, No.-1, Jul 2016, Page 707-713

scholarly journals AYURVEDIC PERSPECTIVE OF SUBCLINICAL HYPOTHYROIDISM

2021 ◽  
Vol 10 (3) ◽  
pp. 3046-3050
Author(s):  
H Rajurkar
Keyword(s):  
Thyroid Gland ◽  
Subclinical Hypothyroidism ◽  
Daily Intake ◽  
Endocrine System ◽  
Primary Hypothyroidism ◽  
Current View ◽  
Thyroid Disorders ◽  
Normal Range ◽  
Secondary Hypothyroidism

Thyroid gland is one of the important glands of the endocrine system and thyroid disorders are the most common disorders amongst the general population worldwide, as well as in india. Hypothyroidism is caused by inadequate function of the thyroid gland called as primary hypothyroidism or by insufficient stimulation by thyroid- stimulating hormones called as secondary hypothyroidism. Current view the thyroid gland is a butterfly shaped gland. It is located inferior to the larynx and anterior to the trachea. It has two lobes connected by the isthmus. It is made of microscopic spherical masses called follicles. A secretary substance is present in the follicle called colloid. Colloid is made of a glycoprotein called as thyroglobulin. Thyroglobulin produces thyroid hormones. They are triiodothyronine (t3), tetraiodothyronine (t4) and calcitonin. Ayurvedic perspective of subclinical hypothyroidism. Management of hypothyroidism with synthetic thyroid hormone derivatives may bring the value of tsh, t3 and t4 to normal range but the daily intake of medicine for lifetime, the known side-effects thereafter and increase in the dosage with time as the disease become chronic, is troublesome for the patients. Also the quality of life of the patients taking medicine regularly for long durations is compromised.

scholarly journals Frequency of Dyslipidemia in Patients Having Subclinical Hypothyroidism

2016 ◽  
Vol 3 (01) ◽  
pp. 22-26
Author(s):  
Shah Zeb ◽  
Shafaq Naz ◽  
Najeeb Ullah
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Sample Size ◽  
Subclinical Hypothyroidism ◽  
Hormone Receptors ◽  
Sample Size Calculation ◽  
Sampling Technique ◽  
Thyroid Stimulating Hormone ◽  
The Body ◽  
Cross Sectional

INTRODUCTIONThyroid hormone by binding to the thyroid hormone receptors affects metabolism and growth in nearly all tissues of the body. Thyroid hormones play vital role in the synthesis and metabolism of lipids. The reduced secretion of thyroxine (T4) and triiodothyronine (T3) from the thyroid gland results in hypothyroidism. The subclinical hypothyroidism (SH) is term used for the condition in which there is small elevation of thyroid stimulating hormone (TSH) in the presence of normal thyroid hormone levels. Disorders of thyroid gland are the second most common endocrine abnormalities globally after diabetes mellitus.OBJECTIVETo determinethe frequency of dyslipidemia in patients having subclinical hypothyroidism.METHODOLOGYThis study was conducted at Naseer Teaching Hospital, Peshawar. Duration of the study was one years and the study design was descriptive cross sectional study. The total sample size was 136 patients presenting with subclinical hypothyroidism taking 34.31% proportion of dyslipidemia in subclinical hypothyroid patients12, 95% confidence interval and 8 % margin of error; using WHO software for sample size calculation. More over consecutive (non-probability sampling) technique was used for sample collection.RESULTSIn this study mean age was 40 years with SD 1.26. Sixty three percent patients were female and 37% patients were male. Seventy percent patients had dyslipidemia while 30% patients didn’t have dyslipidemia.CONCLUSIONThe current study shows that the incidence of dyslipidemia was found to be in patients having subclinical hypothyroidism.

Modern approaches to the diagnosis and treatment of nodular nontoxic lesions of the thyroid gland

2019 ◽  
Vol 25 (2-3) ◽  
pp. 46-57
Author(s):  
Ye.V. Pleshano ◽  
◽  
A.M. Urbanovych ◽  
V.I Kolomiytsev ◽  
Yu.P. Dovhan ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Diagnosis And Treatment

scholarly journals The Diagnosis and Therapy of Degenerative Knee Joint Disease: Expert Consensus from the Chinese Pain Medicine Panel

2018 ◽  
Vol 2018 ◽  
pp. 1-14 ◽  
Author(s):  
Dong Huang ◽  
Yan-Qing Liu ◽  
Li-Shuang Liang ◽  
Xue-Wu Lin ◽  
Tao Song ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Diagnosis And Treatment ◽  
Joint Disease ◽  
Knee Joints ◽  
Reproduction Rate ◽  
Pain Specialist ◽  
Chinese Association ◽  
The One ◽  
Almost All ◽  
Based Medicine

At present, there are many constantly updated guidelines and consensuses on the diagnosis and treatment of osteoarthritis both at home and abroad. The recommendations established using methods of evidence-based medicine has experienced strict research on controlling bias and promoting reproduction rate. As a result, the previous evidence was reevaluated, and a lot of changes were provoked in the diagnosis and treatment concept of osteoarthritis. However, several methods not recommended by foreign guidelines are still in use in the current clinical practice in China. On the one hand, Chinese experts have not reached extensive consensus on whether it is necessary to make changes according to foreign guidelines. On the other hand, almost all the current relevant guidelines are on osteoarthritis, but the lesions around knee joints which, as a whole, bear the largest weight in human body, cannot be ignored. For this purpose, Chinese Association for the Study of Pain (CASP) organized some leading experts to formulate this Chinese Pain Specialist Consensus on the diagnosis and treatment of degenerative knee osteoarthritis (DKOA) in combination with the guidelines in foreign countries and the expert experience of clinical practice in China. The consensus, which includes the definition, pathophysiology, epidemiology, clinical manifestation, diagnostic criteria, and treatments of DKOA, is intended to be used by first-line doctors, including pain physicians to manage patients with DKOA.

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