The state of the vascular system in the children and adolescents presenting with metabolic syndrome

2014 ◽  
Vol 60 (2) ◽  
pp. 8-12 ◽  
Author(s):  
N V Bolotova ◽  
N V Posokhova ◽  
E P Novikova ◽  
E G Dronova ◽  
E A Evseeva

It was studied the state of the vascular wall at metabolic syndrome (MS) in children and adolescents. The study included two groups of children: 45 people with MS and 25 patients with simple obesity. With the help of the device Vasotens assessed indicators of vascular stiffness: pulse wave velocity in the aorta, the indices of stiffness and augmentation of the peripheral arteries and the aorta, the maximum rate of rise in blood pressure. The study showed that 70% of children with MS increased arterial stiffness and thickness of the vascular wall. The rigidity of the vascular wall in children with MS revealed a 3.5 times more likely than children with simple obesity. Pulse wave velocity is a predictor of hypertension and has a high correlation with SDS IMT.

2021 ◽  
Vol 55 (6) ◽  
pp. 23-27
Author(s):  
E.S. Luchitskaya ◽  
◽  
I.I. Funtova ◽  
J. Tank ◽  
H. Reuter ◽  
...  

The article covers the studies of the vascular wall functioning in cosmonauts using the data of pulse wave velocity as a biomarker of early vascular aging. The investigations were performed with the use of device Mobilograph twice before launch, every 30 days of 6-month ISS missions and on days 4 and 8 of recovery. Pulse wave velocity has never exceeded threshold values suggesting that participation in low-Earth orbital missions does not put at risk cardiac health threatening with vascular pathologies. Yet, the conclusion can be premature given the limited potentialities of the method and hardware used in the investigation.


Author(s):  
Erzsébet Valéria Hidvégi ◽  
Andrea Emese Jakab ◽  
Zsófia Lenkey ◽  
Csaba Bereczki ◽  
Attila Cziráki ◽  
...  

2019 ◽  
Vol 8 (12) ◽  
pp. 2090
Author(s):  
Iván Cavero-Redondo ◽  
Vicente Martínez-Vizcaíno ◽  
Celia Álvarez-Bueno ◽  
Cristina Agudo-Conde ◽  
Cristina Lugones-Sánchez ◽  
...  

(1) Background: To assess the suitability of replacing conventional markers used for insulin resistance and dysglycemia by HbA1c in both the quantitative and qualitative metabolic syndrome (MetS) definition criteria; (2) Methods: Confirmatory factorial analysis was used to compare three quantitative definitions of MetS that consisted of many single-factor models, one of which included HbA1c as the dysglycemia indicator. After that, the model with the better goodness-of-fit was selected. Furthermore, a new MetS qualitative definition was proposed by replacing fasting plasma glucose with HbA1c > 5.7% in the International Diabetes Federation (IDF) definition. The clinical performance of these two MetS criteria (IDF and IDF-modified including HbA1c as the dysglycemia indicator) to predict vascular damage (pulse wave velocity [PWv], intima media thickness [IMT] and albumin-to-creatinine ratio [ACR]) was estimated; (3) Results: The single-factor model including HbA1c showed the better goodness-of-fit (χ2 = 2.45, df = 2, p = 0.293, CFI = 0.999, SRMR = 0.010). Additionally, the IDF-modified criteria gained in clinical performance to predict vascular damage (diagnostic Odds Ratio: 6.94, 1.34 and 1.90) for pulse wave velocity (PWv), intima media thickness (IMT) and albumin-to-creatinine ratio (ACR), respectively; and (4) Conclusions: These data suggest that HbA1c could be considered as a useful component to be included in the MetS definition.


2015 ◽  
Vol 28 (12) ◽  
pp. 1480-1488 ◽  
Author(s):  
Daniela Thurn ◽  
Anke Doyon ◽  
Betul Sözeri ◽  
Aysun K. Bayazit ◽  
Nur Canpolat ◽  
...  

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