scholarly journals Experiencia Quirúrgica en el Manejo del Cáncer de Recto. Hospital de SOLCA, Guayaquil – Ecuador

2020 ◽  
Vol 12 (2) ◽  
pp. 92-97
Author(s):  
Carlos Humberto Malatay González ◽  
Juan Bernardo Pazmiño Palacios ◽  
Luis Andrés Idrovo Murillo ◽  
Jhónatan Miguel Siguencia Muñoz ◽  
Adriana Ximena Bravo Andrade
Keyword(s):  
Colorectal Cancer ◽  
Neoadjuvant Therapy ◽  
Clinical Stage ◽  
Cross Sectional Study ◽  
Histological Type ◽  
Stage Iii ◽  
Malignant Neoplasms ◽  
Advanced Clinical Stage ◽  
Cross Sectional ◽  
Common Histological Type

BACKGROUND: Colorectal cancer is the third most common among malignant neoplasms worldwide. Treatment choice depends on the location of the tumor, among other factors, and varies from local excision to abdominoperineal resection, adjuvant or neoadjuvant therapy can be needed, depending on clinical stage. The purpose of this study was to determine the most common histological type of rectal cancer, establish the most frequent clinical stage at diagnosis, the most common surgical technique and complications. METHODOLOGY: A cross-sectional study was carried out, with 160 patients treated in the digestive surgery service of Hospital SOLCA, Guayaquil – Ecuador, between January 2011 and December 2016, with colorectal cancer histologically diagnosed and treated surgically. RESULTS: Female sex was the most affected, with 65.7%, 63.1% of the patients were diagnosed at stage III, adenocarcinoma was the most common histological type (73.7%), the tumor was more frequently located at a low level, in 67.5% of the patients. Surgery was scheduled for 83.7% of the patients, derivative colostomy was the most common surgical procedure for treatment (48.8%), and the most common complications were those related to the ostomy, in 9.4% of the patients. Immediate mortality was 1.2% and late mortality was 8.1%. CONCLUSION: This study evidenced that colorectal cancer affected with more frequency to women, mainly to people over 60 years old. Most of the patients were diagnosed with advanced clinical stage (III) carcinoma, most frequently adenocarcinoma. Derivative colostomy was the procedure of choice for most of the patients, most of them needed neoadjuvant therapy too. The most common postsurgical complications were those related to ostomies.

scholarly journals Anemia and its determinants among TB-HIV co-infected adults of ART naïve in two public hospitals of Mekelle, Ethiopia: a facility based cross-sectional study

2019 ◽  
Author(s):  
Kebede Embaye Gezae ◽  
Kiflom Hagos Mebrahtu ◽  
Assefa Ayalew G/silasse
Keyword(s):  
Functional Status ◽  
Clinical Stage ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
Sub Saharan Africa ◽  
Stage Iii ◽  
Limited Information ◽  
Sectional Study ◽  
Advanced Clinical Stage ◽  
Cross Sectional

Abstract Background Anemia has up to 87% prevalence in high Tuberculosis (TB) and HIV burden settings of the Sub-Saharan Africa (SSA) including Ethiopia. It increases Lost to follow up (LTFU) rate, reduces quality of life and shortens the life expectancy of TB-HIV patients. Despite these facts, there is limited information on anemia and its determinants among TB-HIV adults of ART naïve in Ethiopia in general. Hence, the current study will partly fill the gap in the setting particularily.Methods A facility based cross-sectional study was conducted among 305 TB-HIV co-infected patients of ART naïve who have been started treatment from January, 2009 to December, 2017 in two public hospital of Mekelle, Ethiopia by reviewing an ART register and patient medical charts. A Generalized Linear Model (GLM) of binomial family with link function logit (logit model) was fitted to identify the statistically significant determinants of anemia. Finally, the decision was made based on the 95% Confidence Interval (95% CI) and the magnitude of association was measured based on the Adjusted Odds ratio (Adj. OR).Results At baseline, the cumulative prevalence of anemia was 59.0% (95% CI: 53.3% – 64.6%) where the prevalence of mild, moderate and severe anemia’s 24.6%, 28.2% and 6.2%, respectively. Female sex ((Adj.OR = 0.379; 95% CI: 0.226 – 0.635) and Body Mass Index (Adj. OR = 0.897, 95% CI: 0.823 - 0.977) reduces the odds of developing anemia whereas baseline ambulatory functional status (Adj. OR = 2.302; 95% CI: 1.293 - 4.097), Bedridden functional status (Adj. OR = 2.352; 95% CI: 1.074 - 5.149), HIV Clinical stage III (Adj. OR = 2.987; 95% CI: 1.226-7.279) and HIV Clinical stage IV (Adj. OR = 3.056; 95% CI: 1.219 - 7.657) increases the odds of anemia in TB-HIV co-infected adults of ART naïve in the current study.Conclusion Six in every ten TB-HIV co-infected adults of ART naïve developed anemia at baseline. Therefore, curious attention has to be given to undernourished, advanced clinical stage (III and IV) and non-working functional status TB-HIV adults to reducing anemia associated bad consequences.

scholarly journals A study on peripheral neuropathy in HIV infected patients: clinicoepidemiological and electrophysiological profile

2018 ◽  
Vol 6 (10) ◽  
pp. 3226
Author(s):  
K. Gunasekaran ◽  
S. Sivakumar
Keyword(s):  
Peripheral Neuropathy ◽  
Clinical Stage ◽  
Symptomatic Relief ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Antiretroviral Drugs ◽  
Neurologic Complication ◽  
Advanced Clinical Stage ◽  
Cross Sectional ◽  
Infected People

Background: Peripheral neuropathy is one among the commonest HIV-associated neurologic complications. The spectrum and the frequency of this complication are changing due to the introduction of new antiretroviral drugs, aging of the HIV-infected people, etc. Hence there is need for a better understanding of these complications and their pathogenesis. This study was done with the aim of finding out the risk factors, clinical characteristics and various types and patterns of peripheral neuropathy in HIV infected patients of our region.Methods: This study was a cross sectional study conducted for about a period of one year. Patients attending the out patient department of anti retroviral therapy (ART) centre were taken for the study. Selected patients were analysed for the signs and symptoms of peripheral neuropathy and they underwent electrophysiological study.Results: Prevalence of peripheral neuropathy in HIV infected patients in our study population was 43.3%. Peripheral neuropathy was seen more in patients with advanced clinical stage and increasing age. Distal symmetric polyneuropathy was the commonest type. Common pathological pattern of neuropathy was mixed (both axonal and demyelination) neuropathy.Conclusions: As peripheral neuropathy is a common HIV-associated neurologic complication, large number of studies are needed to elucidate the mechanisms leading to peripheral neuropathy in HIV infected patients, which in turn will allow for the development of effective therapies that provide adequate symptomatic relief and halt or reverse the damage to the nerves.

scholarly journals Prevalence of Appendical Metastasis in Primary Surgery of Ovarian Epithelial Cancer

2020 ◽  
pp. 117-120
Author(s):  
Laila Nuranna ◽  
Jan H. Amili ◽  
Sigit Purbadi ◽  
Nessyah Fatahan
Keyword(s):  
Ovarian Cancer ◽  
Clinical Stage ◽  
Stage Iv ◽  
Cross Sectional Study ◽  
Stage Iii ◽  
Epithelial Cancer ◽  
Cross Sectional ◽  
Chronic Appendicitis ◽  
Primary Surgery ◽  
Ovarian Epithelial Cancer

Objective: To determine the prevalence of metastasis to appendix from primary surgery of ovarian epithelial cancer at National General Hospital Dr. Cipto Mangunkusumo (RSCM), Indonesia.Methods: A cross sectional study was done using ovarian epithelial cancer patient medical record whose primary ovarian cancer and appendectomy surgery were conducted on July to December 2019 at RSCM. Patients without appendix histopatology result and previous chemotherapy were excluded in this study. Consecutive method and random sampling were used in this study.Results: : A total of 80 subjects were included in this study. Subjects have average age of 48 years old. Out of all samples, 43 samples (53.8%) were defined as stage I patient, 7 subjects (8.8%) as stage II, 30 subjects (37.5%) as stage III, and none as stage IV. Appendectomy were done and eight subjects (10%) experienced metastasis to appendix. A total of 19 subjects (23.8%) had chronic appendicitis and 53 subjects (66.3%) did not have metastasis to the appendix. Among eight subjects having appendix involvement, 4 had mucinous histology, 2 serous, and 2 endometrioid. Six out of eight were diagnosed at clinical stage III and two were diagnosed at stage I.Conclusion: The prevalence of appendix metastases from primary surgery in ovarian epithelial cancer at RSCM was 10%. Based on this research, appendectomy can be considered on ovarian cancer surgeryKeywords:    appendix, metastasis, ovarian cancer.   Abstrak Tujuan: Mengetahui prevalensi metastasis kanker epitelial ovarium ke apendiks pada pembedahan primer kanker epitelial ovarium di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (RSCM), Indonesia. Metode: Penelitian ini merupakan studi potong lintang menggunakan data rekam medis pasien kanker ovarium epitelial yang menjalani pembedahan primer dan apendiktomi pada bulan Juli hingga Desember 2019 di RSCM Pasien tanpa histopatologi apendiks atau pernah dilakukan kemoterapi sebelumnya dieksklusi dari penelitian. Digunakan metode pengambilan sampel secara acak. Hasil: Didapatkan 80 subjek penelitian yang diikutsertakan dalam penelitian. Dari 80 subjek penelitian, didapatkan rerata usia 48 tahun. Sebanyak 43 subjek (53,8%) didiagnosis dengan stadium I, 7 subjek (8,8%) sebagai stadium II, 30 subjek (37,5%) stadium III. Dari 80 subjek yang menjalani apendiktomi, didapatkan 8 subjek (10%) anak sebar ke apendiks, 19 subjek (23,8 %) apendisitis kronis, 53 subjek (66,3%) tidak terdapat anak sebar. Dari 8 subjek yang terdapat anak sebar ke apendiks dengan temuan histologi 4 musinosum, 2 serosum, 2 endometroid. Sebanyak enam dari delapan subjek terdiagnosis pada stadium klinis stadium III dan dua lainnya pada stadium klinis satu. Kesimpulan: Prevalensi metastasis apendiks pada operasi primer kanker ovarium epitelial di RSCM adalah sebesar 10%. Berdasarkan hasil penelitian ini, apendektomi dapat dipertimbangkan dilakukan pada pembedahan baik stadium awal maupun stadium lanjut.Kata kunci: , apendiks , kanker ovarium, metastatis

scholarly journals Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study

2019 ◽  
Vol 15 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Julia de Mello Ramirez Medina ◽  
◽  
Ingrid de Araujo Trugilho ◽  
Giovanna Nunes Belo Mendes ◽  
Josiel Guedes Silva ◽  
...  
Keyword(s):  
Clinical Stage ◽  
Cross Sectional Study ◽  
Stage At Diagnosis ◽  
Health Related Quality ◽  
Sectional Study ◽  
Advanced Clinical Stage ◽  
Cross Sectional ◽  
Related Quality ◽  
Health Related

scholarly journals Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yacir El Alami ◽  
Hajar Essangri ◽  
Mohammed Anass Majbar ◽  
Saber Boutayeb ◽  
Said Benamr ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Discriminant Validity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Related Quality ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

Su1944 Disparities in the Presentation and Treatment of Colorectal Cancer in Florida: A Cross Sectional Study

2015 ◽  
Vol 148 (4) ◽  
pp. S-557
Author(s):  
Eduardo A. Rodriguez ◽  
Sri Kartik A. Valluri ◽  
Hua Li ◽  
Leonardo Tamariz ◽  
Ana Palacio ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

Awareness of basic life support among undergraduate medical students in Syria, Iraq and Jordan: a cross sectional study

2021 ◽  
Author(s):  
Mohammad Nour Shashaa ◽  
Mohamad Shadi Alkarrash ◽  
Mohammad Nour Kitaz ◽  
Roaa Rhayim ◽  
Mohammed Ismail ◽  
...  
Keyword(s):  
Medical Students ◽  
Basic Life Support ◽  
Life Support ◽  
Clinical Stage ◽  
Sudden Cardiac Arrest ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Undergraduate Medical Students ◽  
Cross Sectional ◽  
Significant Difference

Abstract Background Sudden cardiac arrest considers one of the most leading cause for death in all over the world. It is important for all medical students to train basic life support. This study evaluated the awareness of basic life support among medical students. Methods An electronic questionnaire based cross sectional study was conducted in November 2020 among 2114 medical student in Syria, Iraq and Jordan. We evaluated BLS skills according to mean score. A chi-squared test was used to determine if there were differences between those who attended a basic life support course and those who did not. Results 1656 of the participants (78.3%) stated that they did not attend a basic life support course. There was a significant difference between the participants from different countries where the mean score in Syria, Jordan and Iraq was 18.3, 24.3 and 18.8 respectively (p < 0.05). The participants were divided into 3 level according to total score; low (0–12), moderate (13–24) and high (25–37). In total, 18.3%, 72.8% and 8.9% of participants had high, intermediate and low level respectively. Conclusions The overall knowledge of basic life support among medical students is not adequate and need significant improvements. This study showed that an attendance a basic life support course previously had an effect on knowledge level. Hence, there is an urgent need to apply basic life support courses into the pre-clinical stage at universities.

Sign in / Sign up

Export Citation Format

Share Document