Anemia and its determinants among TB-HIV co-infected adults of ART naïve in two public hospitals of Mekelle, Ethiopia: a facility based cross-sectional study

Abstract Background Anemia has up to 87% prevalence in high Tuberculosis (TB) and HIV burden settings of the Sub-Saharan Africa (SSA) including Ethiopia. It increases Lost to follow up (LTFU) rate, reduces quality of life and shortens the life expectancy of TB-HIV patients. Despite these facts, there is limited information on anemia and its determinants among TB-HIV adults of ART naïve in Ethiopia in general. Hence, the current study will partly fill the gap in the setting particularily.Methods A facility based cross-sectional study was conducted among 305 TB-HIV co-infected patients of ART naïve who have been started treatment from January, 2009 to December, 2017 in two public hospital of Mekelle, Ethiopia by reviewing an ART register and patient medical charts. A Generalized Linear Model (GLM) of binomial family with link function logit (logit model) was fitted to identify the statistically significant determinants of anemia. Finally, the decision was made based on the 95% Confidence Interval (95% CI) and the magnitude of association was measured based on the Adjusted Odds ratio (Adj. OR).Results At baseline, the cumulative prevalence of anemia was 59.0% (95% CI: 53.3% – 64.6%) where the prevalence of mild, moderate and severe anemia’s 24.6%, 28.2% and 6.2%, respectively. Female sex ((Adj.OR = 0.379; 95% CI: 0.226 – 0.635) and Body Mass Index (Adj. OR = 0.897, 95% CI: 0.823 - 0.977) reduces the odds of developing anemia whereas baseline ambulatory functional status (Adj. OR = 2.302; 95% CI: 1.293 - 4.097), Bedridden functional status (Adj. OR = 2.352; 95% CI: 1.074 - 5.149), HIV Clinical stage III (Adj. OR = 2.987; 95% CI: 1.226-7.279) and HIV Clinical stage IV (Adj. OR = 3.056; 95% CI: 1.219 - 7.657) increases the odds of anemia in TB-HIV co-infected adults of ART naïve in the current study.Conclusion Six in every ten TB-HIV co-infected adults of ART naïve developed anemia at baseline. Therefore, curious attention has to be given to undernourished, advanced clinical stage (III and IV) and non-working functional status TB-HIV adults to reducing anemia associated bad consequences.

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Experiencia Quirúrgica en el Manejo del Cáncer de Recto. Hospital de SOLCA, Guayaquil – Ecuador

Revista Médica del Hospital José Carrasco Arteaga ◽

10.14410/2020.12.2.ao.13 ◽

2020 ◽

Vol 12 (2) ◽

pp. 92-97

Author(s):

Carlos Humberto Malatay González ◽

Juan Bernardo Pazmiño Palacios ◽

Luis Andrés Idrovo Murillo ◽

Jhónatan Miguel Siguencia Muñoz ◽

Adriana Ximena Bravo Andrade

Keyword(s):

Colorectal Cancer ◽

Neoadjuvant Therapy ◽

Clinical Stage ◽

Cross Sectional Study ◽

Histological Type ◽

Stage Iii ◽

Malignant Neoplasms ◽

Advanced Clinical Stage ◽

Cross Sectional ◽

Common Histological Type

BACKGROUND: Colorectal cancer is the third most common among malignant neoplasms worldwide. Treatment choice depends on the location of the tumor, among other factors, and varies from local excision to abdominoperineal resection, adjuvant or neoadjuvant therapy can be needed, depending on clinical stage. The purpose of this study was to determine the most common histological type of rectal cancer, establish the most frequent clinical stage at diagnosis, the most common surgical technique and complications. METHODOLOGY: A cross-sectional study was carried out, with 160 patients treated in the digestive surgery service of Hospital SOLCA, Guayaquil – Ecuador, between January 2011 and December 2016, with colorectal cancer histologically diagnosed and treated surgically. RESULTS: Female sex was the most affected, with 65.7%, 63.1% of the patients were diagnosed at stage III, adenocarcinoma was the most common histological type (73.7%), the tumor was more frequently located at a low level, in 67.5% of the patients. Surgery was scheduled for 83.7% of the patients, derivative colostomy was the most common surgical procedure for treatment (48.8%), and the most common complications were those related to the ostomy, in 9.4% of the patients. Immediate mortality was 1.2% and late mortality was 8.1%. CONCLUSION: This study evidenced that colorectal cancer affected with more frequency to women, mainly to people over 60 years old. Most of the patients were diagnosed with advanced clinical stage (III) carcinoma, most frequently adenocarcinoma. Derivative colostomy was the procedure of choice for most of the patients, most of them needed neoadjuvant therapy too. The most common postsurgical complications were those related to ostomies.

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Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study

European Journal of Breast Health ◽

10.5152/ejbh.2018.4297 ◽

2019 ◽

Vol 15 (1) ◽

pp. 26-31 ◽

Cited By ~ 8

Author(s):

Julia de Mello Ramirez Medina ◽

◽

Ingrid de Araujo Trugilho ◽

Giovanna Nunes Belo Mendes ◽

Josiel Guedes Silva ◽

...

Keyword(s):

Clinical Stage ◽

Cross Sectional Study ◽

Stage At Diagnosis ◽

Health Related Quality ◽

Sectional Study ◽

Advanced Clinical Stage ◽

Cross Sectional ◽

Related Quality ◽

Health Related

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Maternal healthcare utilsation and complete childhood vaccination in sub-Saharan Africa: a cross-sectional study of 29 nationally representative surveys

BMJ Open ◽

10.1136/bmjopen-2020-045992 ◽

2021 ◽

Vol 11 (5) ◽

pp. e045992

Author(s):

Eugene Budu ◽

Bright Opoku Ahinkorah ◽

Richard Gyan Aboagye ◽

Ebenezer Kwesi Armah-Ansah ◽

Abdul-Aziz Seidu ◽

...

Keyword(s):

Healthcare Utilisation ◽

Cross Sectional Study ◽

Sub Saharan Africa ◽

Childhood Vaccination ◽

Outcome Variable ◽

Service Utilisation ◽

Sectional Study ◽

Maternal Healthcare ◽

Cross Sectional ◽

Sub Saharan

ObjectiveThe objective of the study was to examine the association between maternal healthcare utilisation and complete childhood vaccination in sub-Saharan Africa.DesignOur study was a cross-sectional study that used pooled data from 29 countries in sub-Saharan Africa.ParticipantsA total of 60 964 mothers of children aged 11–23 months were included in the study.Outcome variablesThe main outcome variable was complete childhood vaccination. The explanatory variables were number of antenatal care (ANC) visits, assistance during delivery and postnatal care (PNC).ResultsThe average prevalence of complete childhood vaccination was 85.6%, ranging from 67.0% in Ethiopia to 98.5% in Namibia. Our adjusted model, children whose mothers had a maximum of three ANC visits were 56% less likely to have complete vaccination, compared with those who had at least four ANC visits (adjusted OR (aOR)=0.44, 95% CI 0.42 to 0.46). Children whose mothers were assisted by traditional birth attendant/other (aOR=0.43, 95% CI 0.41 to 0.56) had lower odds of complete vaccination. The odds of complete vaccination were lower among children whose mothers did not attend PNC clinics (aOR=0.26, 95% CI 0.24 to 0.29) as against those whose mothers attended.ConclusionThe study found significant variations in complete childhood vaccination across countries in sub-Saharan Africa. Maternal healthcare utilisation (ANC visits, skilled birth delivery, PNC attendance) had significant association with complete childhood vaccination. These findings suggest that programmes, interventions and strategies aimed at improving vaccination should incorporate interventions that can enhance maternal healthcare utilisation. Such interventions can include education and sensitisation, reducing cost of maternal healthcare and encouraging male involvement in maternal healthcare service utilisation.

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Constrains for seeking post-abortion care among adolescents and young women in Guangzhou, China: a cross-sectional study

BMC Health Services Research ◽

10.1186/s12913-021-06263-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yiding Wang ◽

Jinzhi Liu ◽

Ribo Xiong ◽

Yan Liu

Keyword(s):

Young Women ◽

Cross Sectional Study ◽

Public Hospitals ◽

Sectional Study ◽

Cross Sectional ◽

Services Utilization ◽

Abortion Care ◽

Post Abortion Care ◽

Post Abortion ◽

Youth Friendly

Abstract Background In China, post-abortion care (PAC) services mainly focus on married couples, such that adolescents and unmarried young womenhave limited access to those services for contraception counseling. The provision of youth-friendly PAC services in public hospitals is a new concept in China. This study examined the magnitude of PAC services utilization as well as factors influencing it’s uptake among adolescents and young women in Guangzhou, China. Methods A cross-sectional study was performed from 1st March 2020 to 30th September 2020 using anonymous self-administered questionnaire among 688 women aged 15–24 years in Tianhe district, Guangzhou. The Multivariate logistic regression was used to determine factors that were significantly associated with the uptake of PAC services. Results The magnitude of PAC services utilization was 35.9% among adolescents and young women in Guangzhou, China. Students were 69.0% significantly less likely to use PAC services compared to women who had no job. Immigrants were 59.0% significantly less likely to use PAC services than their native counterparts. Women who had a feeling of stigma were 70.0% significantly less likely to use PAC services compared to those who did not feel stigmatized. Conclusions The study highlights the need to strengthen youth-friendly PAC services provision, and emphasizes the importance of education about both family planning and abortion services among disadvantaged sub-groups of women in the study setting.

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A cross-sectional study reporting concussion exposure, assessment and management in Western Australian general practice

BMC Family Practice ◽

10.1186/s12875-021-01384-1 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Elizabeth Thomas ◽

HuiJun Chih ◽

Belinda Gabbe ◽

Melinda Fitzgerald ◽

Gill Cowen

Keyword(s):

General Practice ◽

Cross Sectional Study ◽

Limited Information ◽

Sectional Study ◽

Cross Sectional ◽

Usual Practice ◽

Exact Test ◽

Concussion Management ◽

Practice Knowledge ◽

Western Australian

Abstract Background General Practitioners (GPs) may be called upon to assess patients who have sustained a concussion despite limited information being available at this assessment. Information relating to how concussion is actually being assessed and managed in General Practice is scarce. This study aimed to identify characteristics of current Western Australian (WA) GP exposure to patients with concussion, factors associated with GPs’ knowledge of concussion, confidence of GPs in diagnosing and managing patients with concussion, typical referral practices and familiarity of GPs with guidelines. Methods In this cross-sectional study, GPs in WA were recruited via the RACGP WA newsletter and shareGP and the consented GPs completed an electronic survey. Associations were performed using Chi-squared tests or Fisher’s Exact test. Results Sixty-six GPs in WA responded to the survey (response rate = 1.7%). Demographics, usual practice, knowledge, confidence, identification of prolonged recovery as well as guideline and resource awareness of GPs who practised in regional and metropolitan areas were comparable (p > 0.05). Characteristics of GPs were similar between those who identified all symptoms of concussion and distractors correctly and those who did not (p > 0.05). However, 84% of the respondents who had never heard of concussion guidelines were less likely to answer all symptoms and distractors correctly (p = 0.039). Whilst 78% of the GPs who were confident in their diagnoses had heard of guidelines (p = 0.029), confidence in managing concussion was not significantly associated with GPs exposure to guidelines. It should be noted that none of the respondents correctly identified signs of concussion and excluded the distractors. Conclusions Knowledge surrounding concussion guidelines, diagnosis and management varied across GPs in WA. Promotion of available concussion guidelines may assist GPs who lack confidence in making a diagnosis. The lack of association between GPs exposure to guidelines and confidence managing concussion highlights that concussion management may be an area where GPs could benefit from additional education and support.

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The Prevalence of Necrotizing Enterocolitis and Associated Factors Among Enteral Fed Preterm and Low Birth Weight Neonates Admitted in Selected Public Hospitals in Addis Ababa, Ethiopia: A Cross-sectional Study

Global Pediatric Health ◽

10.1177/2333794x211019695 ◽

2021 ◽

Vol 8 ◽

pp. 2333794X2110196

Author(s):

Sitotaw Molla Mekonnen ◽

Daniel Mengistu Bekele ◽

Fikrtemariam Abebe Fenta ◽

Addisu Dabi Wake

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Necrotizing Enterocolitis ◽

Gestational Age ◽

Associated Factors ◽

Addis Ababa ◽

Cross Sectional Study ◽

Public Hospitals ◽

Sectional Study ◽

Cross Sectional

Necrotizing enterocolitis (NEC) remains to be the most critical and frequent gastrointestinal disorder understood in neonatal intensive care units (NICU). The presented study was intended to assess the prevalence of NEC and associated factors among enteral Fed preterm and low birth weight neonates. Institution based retrospective cross-sectional study was conducted on 350 enteral Fed preterm and low birth weight neonates who were admitted at selected public hospitals of Addis Ababa from March 25/2020 to May 10/2020. The data were collected through neonates’ medical record chart review. A total of 350 participants were enrolled in to the study with the response rate of 99.43%. One hundred eighty-four (52.6%) of them were male. The majority 123 (35.1%) of them were (32 + 1 to 34) weeks gestational age. The prevalence of NEC was (25.4%) (n = 89, [95% CI; 21.1, 30.0]). Being ≤28 weeks gestational age (AOR = 3.94, 95% CI [2.67, 9.97]), being (28 + 1 to 32 weeks) gestational age (AOR = 3.65, 95% CI [2.21, 8.31]), birth weight of 1000 to 1499 g (AOR = 2.29, 95% CI [1.22, 4.33]), APGAR score ≤3 (AOR = 2.34, 95% CI [1.32, 4.16]), prolonged labor (AOR = 2.21, 95% CI [1.35, 6.38]), maternal chronic disease particularly hypertension (AOR = 3.2, 95% CI [1.70, 5.90]), chorioamnionitis (AOR = 4.8, 95% CI [3.9, 13]), failure to breath/resuscitated (AOR = 2.1, 95% CI [1.7, 4.4]), CPAP ventilation (AOR = 3.7, 95% CI [1.50, 12.70]), mixed milk (AOR = 3.58, 95% CI [2.16, 9.32]) were factors significantly associated with NEC. Finally, the prevalence of NEC in the study area was high. So that, initiating the programs that could minimize this problem is required to avoid the substantial morbidity and mortality associated with NEC.

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Functional status and oral health in patients with amyotrophic lateral sclerosis: A cross-sectional study

Neurorehabilitation ◽

10.3233/nre-201537 ◽

2020 ◽

pp. 1-9

Author(s):

Alessandro de Sire ◽

Marco Invernizzi ◽

Martina Ferrillo ◽

Francesca Gimigliano ◽

Alessio Baricich ◽

...

Keyword(s):

Health Care ◽

Health Status ◽

Oral Health ◽

Functional Status ◽

Cross Sectional Study ◽

Oral Health Status ◽

Multidisciplinary Management ◽

Sectional Study ◽

Cross Sectional ◽

Lateral Sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting upper and lower motor neurons. The current practice of caring for patients affected by ALS involves a multidisciplinary team without any indication about oral health care. OBJECTIVE: We sought to investigate the functional status and oral health in patients with ALS to define a specific multidisciplinary management. METHODS: In this cross-sectional study, we included patients affected by ALS, evaluating their functional status, using the Revised ALS Functional Rating Scale (ALSFRS-R) and their oral health status through specific parameters, including Brief Oral Health Status Examination (BOHSE), Winkel Tongue Coating Index (WTCI), and Oral Food Debris Index (OFDI). RESULTS: All 37 patients (mean age: 61.19±11.56 years) showed a poor oral status, independent from the functional status and strictly correlated to the severity of sialorrhea (p = 0.01). OFDI index was negatively correlated with the ALSFRS-R upper limb (p = 0.03). Patients with bulbar onset had significantly lower ability to perform adequate tongue movements in terms of protrusion (p = 0.006) and lateralization (p < 0.001). Significant negative correlations between survival rate and BOHSE (p = 0.03) was found. CONCLUSIONS: Taken together, our findings showed that a poor oral health status might be correlated to a worse functional status and survival time. Thus, an adequate oral health care and rehabilitation should be considered as crucial in the multidisciplinary management of patients with ALS.

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