scholarly journals Nervous system injury in alcoholic disease

2019 ◽  
Vol 11 (2S) ◽  
pp. 83-88
Author(s):  
O. E. Zinovyeva ◽  
N. V. Vashchenko ◽  
O. E. Mozgovaya ◽  
T. A. Yanakaeva ◽  
A. Yu. Emelyanova
Keyword(s):  
Nervous System ◽  
Peripheral Nervous System ◽  
Alcohol Intoxication ◽  
Clinical Manifestations ◽  
Symptomatic Treatment ◽  
Chronic Alcohol ◽  
Neurological Manifestations ◽  
Chronic Alcohol Intoxication ◽  
Alcoholic Disease

The paper considers various variants of nervous system injury in alcoholic disease. It discusses the epidemiology, pathogenesis, diagnosis, and clinical manifestations of central and peripheral nervous system lesions in the presence of acute and chronic alcohol intoxication. Attention is paid to the issues of etiotropic, pathogenetic, and symptomatic treatment for neurological manifestations of alcoholic disease and to the role of neurotropic B vitamins in the treatment of alcohol-induced deficiency and non-deficiency states.

scholarly journals OBJECTIFICATION OF LABORATORY DIAGNOSTICS OF ACUTE AND CHRONIC ALCOHOL INTOXICATION WITH USING MODERN BIOCHEMICAL MARKERS

2016 ◽  
Vol 16 ◽  
pp. 385-391
Author(s):  
L. N. Derecha ◽  
V. V. Myasoedov ◽  
V. V. Bondarenko
Keyword(s):  
Biochemical Markers ◽  
Causes Of Death ◽  
Alcohol Intoxication ◽  
Laboratory Diagnostics ◽  
Chronic Alcohol ◽  
Internal Organs ◽  
Laboratory Methods ◽  
Chronic Alcohol Intoxication ◽  
Oncological Diseases ◽  
Alcoholic Disease

The consideration is given to problems of alcoholic disease-pathology, which has recently become so widespread in many countries, and is ranked number three in the causes of death and disability after cardiovascular and oncological diseases. The article highlights the main issues of pathogenesis and diagnostics of the most common affection of internal organs resulted from alcoholic etiology. Special attention is paid to laboratory methods for diagnosing the acute and chronic alcohol intoxication.

P.6.a.003 Oxidative stress and role of salivary peroxidase in acute and chronic alcohol intoxication

2009 ◽  
Vol 19 ◽  
pp. S637
Author(s):  
N. Waszkiewicz ◽  
S.D. Szajda ◽  
B. Konarzewska ◽  
A. Szulc ◽  
M. Waszkiewicz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Alcohol Intoxication ◽  
Chronic Alcohol ◽  
Chronic Alcohol Intoxication

Mallory bodies and their role in the patho- and morphogenesis of alcoholic disease

2021 ◽  
Vol 22 (3) ◽  
pp. 22-26
Author(s):  
V. S. Paukov ◽  
◽  
Y. A. Kirillov ◽  
I. A. Chernov ◽  
◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Active Treatment ◽  
Alcohol Intoxication ◽  
The Body ◽  
Basal Metabolism ◽  
Chronic Alcohol ◽  
Chronic Alcohol Intoxication ◽  
Mallory Bodies ◽  
Alcoholic Hyaline ◽  
Alcoholic Disease

The authors consider alcohol disease (AD) as an independent disease, the pathogenesis of which passes 3 stages: episodic alcohol intoxication, drunkenness and alcoholism. In the last 2 stages, severe changes in organs and tissues develop. In this case, Mallory bodies appear in the liver, which is considered to be a marker of chronic alcohol intoxication (CAI). They are observed in most patients with alcoholism and very rarely in those suffering from alcoholism. The authors believe that the alcoholic hyaline Mallory bodies, appearing in the liver and other organs in CAI, is an autoantigen to which the body responds with an autoimmune inflammatory response that is not curable. Therefore, drunkenness, in which there are no Mallory bodies, is curable when alcohol is consumed within the basal metabolism of the liver and treated by therapists, and the treatment of alcoholism is futile. Therefore, the problem of CAI can be solved only with the active treatment of the stage of drunkenness by therapists with the participation of psychiatrists.

scholarly journals Polyneuropathy following COVID-19 infection: the rehabilitation approach

2021 ◽  
Vol 14 (5) ◽  
pp. e242330
Author(s):  
Ahmad Saif ◽  
Anton Pick
Keyword(s):  
Nervous System ◽  
Critical Illness ◽  
Peripheral Nervous System ◽  
Upper Limb ◽  
Inflammatory Disease ◽  
Pathological Process ◽  
Neurological Manifestations ◽  
Sensorimotor Polyneuropathy ◽  
System Disease ◽  
Symmetrical Pattern

A range of neurological manifestations associated with COVID-19 have been reported in the literature, but the pathogenesis of these have yet to be fully explained. The majority of cases of peripheral nervous system disease published thus far have shown a symmetrical pattern. In contrast, we describe the case of a patient with asymmetrical predominantly upper-limb sensorimotor polyneuropathy following COVID-19 infection, likely due to a multifactorial pathological process involving critical illness neuropathy, mechanical injury and inflammatory disease. His presentation, management and recovery contribute to the understanding of this complex condition and informs rehabilitation approaches.

Features of the sensitivity of the central nervous system of the organism of experimental animals to the effects of certain psychotropic drugs and their combinations against the background of chronic alcohol intoxication in a chronopharmacological experiment

2020 ◽  
pp. 56-62
Author(s):  
E.V. Filippova
Keyword(s):  
Alcohol Intoxication ◽  
Laboratory Animals ◽  
Histological Structure ◽  
Chronic Alcohol ◽  
Behavioral Reactions ◽  
Experimental Animals ◽  
Chronic Alcohol Intoxication ◽  
Psychotropic Action ◽  
Adaptive Effect ◽  
The Central Nervous System

In a chronopharmacological experiment, the effect of two drugs with psychotropic action in combinations on the behavior of laboratory animals subjected to chronic alcohol intoxication was examined. Against the background of a deprimating agent, a decrease in the threshold of sensitivity to electrical irritation and the duration of an aggressive reaction was revealed; an increase in these indicators was established with a combination of a deprimating drug with an antioxidant. It has been shown that the antioxidant has a desynchronizing effect on the behavioral reactions of laboratory animals for two days, which indicates a pronounced adaptive effect. In the case of using combinations of a deprimating agent with an antioxidant, a decrease in the destruction of the histological structure of the myocardium against the background of chronic alcoholization was established.

Sign in / Sign up

Export Citation Format

Share Document