A Study of Clinical Profile, Risk Factors and Outcome in Patients of Cerebral Venous Sinus Thrombosis

2016 ◽  
Vol 3 (12) ◽  
pp. 14-18
Author(s):  
Kapinder Yadav ◽  
Surekha Dabla ◽  
Bhuwan Sharma ◽  
Preeti Yadav ◽  
Surender Kumar ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Clinical Profile ◽  
Venous Sinus Thrombosis

Clinical Profile And Risk Factors of Cerebral Venous Sinus Thrombosis (CVST) in Sudan

2021 ◽  
Author(s):  
Etedal Ahmed A Ibrahim ◽  
Rofiedah Eisa Hassan Mohamed ◽  
Khabab Abbasher Hussien Mohamed Ahmed ◽  
Mohammed Eltahier Abdalla Omer
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Wide Spectrum ◽  
Treatment Options ◽  
Signs And Symptoms ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Venous Sinus Thrombosis

Abstract Background Cerebral venous sinus thrombosis (CVST) is relatively uncommon cause of stroke mainly affects young ladies, with a wide spectrum of symptoms severity and prognosis. In this study we aim to study the clinical profile and Risk Factors of CVST among Sudanese patients in Khartoum state hospitals. Methods This is an observational cross-sectional multi-center hospital based study which covered 37 participants, in three major hospitals in khartoum, with radiologically confirmed Cerebral Venous Sinus Thrombosis (CVST) Results 37 patients were included in this study, The mean age of patients was 38.5 ± 13.4 years, with minimum age of 23 years and maximum of 75 years, the largest group (n = 18, 48.6%) were in the range between “26–35” years, regarding gender distribution (n = 8; 21.6%) were males and the majority of patients were female (n = 29; 78.4%), the commonest presenting feature was headache (n = 35; 94.6%), followed by blurring of vision (n = 25; 67.6%), while seizures is a presenting symptom in nearly half of the patients (n = 17; 45.9%), on examination papilloedema was present in 83.8%. In this study 13.8% were pregnant, 31.0% were postpartum, OCPS user account for 27.%, and No risk factor present in 32.4%. regarding the involved sinus Sagittal Venous Sinus and the transverse sinus were the most affected sinuses. Regarding treatment options: “low molecular weight heparin followed with warfarin” was found in 81.1%, followed with heparin only 10.8%, while the new agents NOACs comprised only 8.1%. Conclusion The study concluded that Cerebral Venous Sinus Thrombosis is mainly a disease of child-bearing women, although significant proportions of men were affected. Cerebral Venous Sinus Thrombosis presents in a wide variety of signs and symptoms.

scholarly journals Cerebral venous sinus thrombosis associated with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection

2021 ◽  
pp. 104-104
Author(s):  
Dragan Nikolic ◽  
Marijana Basta-Nikolic ◽  
Vladimir Manojlovic ◽  
Zeljko Zivanovic ◽  
Sanja Vickovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Severe Acute Respiratory Syndrome ◽  
High Mortality ◽  
Clinical Presentation ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Neurological Symptoms ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis

Introduction/Objective. Coagulopathy induced by severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2) can be an underlying cause of cerebral venous sinus thrombosis (CVST), a less common type of stroke with a variable clinical presentation and high mortality rate. Objective: to present a series of CVST cases associated with SARS-CoV-2 infection. Methods. This retrospective study evaluated clinical, laboratory and radiological presentation, risk factors, barriers to diagnosis, treatment and outcome of patients with SARS-CoV-2 infection induced CVST. Results. The study comprised 6 patients diagnosed with COVID-19 induced CVST during the 18 months period. Majority (66.7%) had no significant risk factors for developing CVST. Median time from initial COVID-19 diagnosis to onset of neurologic deficit was 7 days (interquartile range 0.5-7 days). Clinical presentation comprised non specific neurological symptoms: headache (83.3%) and decreased consciousness (33.3%), together with elevated levels of D-dimer and inflammatory biomarkers. The transverse (n = 4 or 66.7%), superior sagittal sinuses (n = 3 or 50%) and sigmoid sinus (n = 2 or 33.3%) were most commonly affected. Five patients (83.3%) had minimal to no symptoms at discharge (mRS ? 2). In-hospital mortality in our current series was relatively high (16.7%). Conclusion. The high mortality rate of SARS-CoV-2-associated CVST urges clinicians to suspect CVST in patients with a history of COVID-19 infection presenting with non-specific neurological symptoms in order to provide proper treatment and prevent complications.

scholarly journals Clinical characteristics of cerebral venous sinus thrombosis patients with new-onset of headache

2020 ◽  
Author(s):  
Yugang Wang ◽  
Qi Fang
Keyword(s):  
Risk Factors ◽  
Clinical Characteristics ◽  
Sinus Thrombosis ◽  
Chloride Ion ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Younger Age ◽  
Headache Patients ◽  
New Onset

Abstract Objective : This study aimed to assess the clinical characteristics of cerebral venous sinus thrombosis (CVT) patients with new-onset headache and to identify the risk factors for headache in this population.Methods : We retrospectively reviewed the demographic and clinical data of 69 CVT patients recruited between September 2017 and September 2019. Patients were classified into two groups, the headache group and the non-headache group, according to the presence or absence of new-onset headache symptoms at admission. The following characteristics and parameters were measured and analyzed, including gender, age, Diseased sinus amount(DSA), and so on.Results : The incidence of headache was 75% in this cohort. The proportion of female patients in the headache group was higher than that in the non-headache group. Patients in the headache group were younger than those without headache. CVT patients of headache group showed higher LR, BUN, and (ICP)compared to the non-headache group, whereas MCV and levels of protein (CSF) and LDH (CSF) were lower in headache patients. The data also revealed younger age and the increased level of chloride ion CL - (CSF) were the risk factors for the occurrence of headache in CVT patients.Conclusions: The age, LR, MCV, BUN levels, ICP, protein (CSF), and LDH (CSF) in patients with headache were significantly different from those in the non-headache group at admission. Younger age and a level of CL - (CSF) were risk factors for headache in CVT patients. These findings may provide guidance for clinical diagnosis and treatment of CVT.

Cerebral Venous Sinus Thrombosis Risk Factors

2009 ◽  
Vol 4 (2) ◽  
pp. 111-123 ◽  
Author(s):  
Mohammad Saadatnia ◽  
Farzad Fatehi ◽  
Keivan Basiri ◽  
Seyed Ali Mousavi ◽  
Gilda Kinani Mehr
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Venous Sinus Thrombosis ◽  
Thrombosis Risk

scholarly journals Clinical associations, biological risk factors and outcomes of cerebral venous sinus thrombosis

2016 ◽  
Vol 44 (6) ◽  
pp. 1454-1461 ◽  
Author(s):  
Hafize Nalan Gunes ◽  
Burcu Gokce Cokal ◽  
Selda Keskin Guler ◽  
Tahir Kurtulus Yoldas ◽  
Umit Yavuz Malkan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sinus Thrombosis ◽  
Cerebral Venous Sinus Thrombosis ◽  
Venous Sinus ◽  
Common Symptom ◽  
Venous Sinus Thrombosis ◽  
Hospitalization Period ◽  
Wide Range ◽  
Significant Difference ◽  
Clinical Associations

Objective Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disease affecting young adults. The majority of the patients are female. The aim of this study is to assess the clinical associations, risk factors and outcomes of the patients with CVST. Methods The data of 75 patients with CVST admitted to our hospital between 2006 and 2016 were reviewed. Demographic and clinical features and the thrombophilic risk factors of the patients were recorded. The localizations of the thrombi were determined and modified Rankin score at the time of onset and discharge were calculated. Results The majority of our patients (78.7%) were female. Median age was 35 years (16–76). The most common symptom was headache (86.7%). In 82.6% of our patients, inherited or acquired risk factors for thrombosis were detected. Transverse sinus was the most common site of thrombosis followed by sigmoid and superior sagittal sinuses. Two thirds of the patients had involvement of multiple sinuses. The patients with the involvement of sagittal sinus had better disability at the time of admittance ( p = 0.013) while the number of involved sinuses was correlated worse disability ( p = 0.015). The neurologic states in the majority of the patients were improved by the end of the hospitalization period ( p = 0.001). There was no significant difference in disability score at discharge between men and women ( p = 0.080). No patient with CVST died in the hospitalization period. Conclusions This study is one of the largest cohort studies on CVST in our region. The results of the study disclosed that CVST had wide range of clinical manifestations and non-specific symptoms at the beginning. For that reason, in especially high risk groups for thrombosis, the diagnosis of CVST should be kept in mind.

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