scholarly journals The effect of transcutaneous electrical nerve stimulation (TENS) on pain control and phenylethanolamine-N-methyltransferase (PNMT) gene expression after cesarean section

2021 ◽  
Vol 67 (3) ◽  
pp. 153-157
Author(s):  
Wenxiang Chen ◽  
Chunying Liu ◽  
Yongrong Yang ◽  
Lili Tian

Transcutaneous electrical nerve stimulation (TENS) is one of the non-pharmacological methods of pain relief that has been able to reduce pain by 70 to 90% in postoperative pain control. This study aimed to determine the effect of TENS on pain control after cesarean section and its effect on PNMT gene expression. For this purpose, a double-blind randomized clinical trial was performed on 70 Chinese patients with elective cesarean section. Patients were divided into case and control groups. In the case group, TENS and analgesic drugs were used to relieve pain, and in the control group, the only analgesic drug was used. Then the severity of pain, recurrence of pain attacks, the number of analgesic drugs used and the amount of analgesic drug used in the first 24 hours after surgery were evaluated and compared. Blood samples were also taken from patients to evaluate PNMT gene expression. The semi-quantitative RT-PCR was used to study changes in gene expression. The results showed that the group treated with TENS had less pain intensity and less recurrence of pain attacks than the group that received only analgesic medication. Also, the frequency of analgesic drug use and its dose in the TENS group were significantly lower than in the control group. TENS, on the other hand, has been able to greatly reduce the expression of the PNMT gene, which is produced during times of stress. Therefore, it is recommended that TENS be used as a non-invasive and non-pharmacological adjuvant effective in reducing pain after cesarean section.

2014 ◽  
Vol 27 (15) ◽  
pp. 1572-1575 ◽  
Author(s):  
Seda Kayman-Kose ◽  
Dagistan Tolga Arioz ◽  
Hasan Toktas ◽  
Gulengul Koken ◽  
Mine Kanat-Pektas ◽  
...  

2019 ◽  
Vol 14 (1) ◽  
pp. 75-83
Author(s):  
L. Bouafif ◽  
N. Ellouze

Background: Transcutaneous Electrical Nerve Stimulation (TENS) is a non-invasive pain therapy that uses the sensory effects of an electrical current applied to the skin. Some clinical studies demonstrated that this treatment helps to reduce acute and chronic pains, while others gave sometimes contradictory or uncertain conclusions about the performances of this strategy according to pathology classification. The purpose of this study is the development and evaluation of a new modulated version of transcutaneous electrical nerve stimulation called PWM-TENS. The principle is based on an automatic variation of the stimulation parameters (frequency, amplitude, duration, shape, cyclic ratio) according to the pain evolution. Methods: The study was a controlled clinical trial involving 15 participants, divided into 2 groups. The first experimental group performed modulated PWM-TENS electro-stimulation sessions applied to the painful areas 3 to 4 times a day, for one month. The second control group did parallel treatments by Placebo. The evaluation of the pain intensity is done with the Visual Analog Scale (EVA), the DN4 and SF36 questionnaires. Results: The tests and measurements with our embedded PWM-TENS technique demonstrated that we succeeded to increase the analgesic effect after stopping the stimulation and reduced the pain sensation by about 60%. An improvement in pain intensity scores and questionnaires (EVA, DN4), as well as the quality of life score (SF36), was observed. Also, a reduction of the treatment period from 3 to 1 month was also obtained. Conclusion: The first results clinically observed in the PWM-TENS technique are encouraging. The findings of this study confirm that this noninvasive strategy is suitable and useful for acute pains coming from the nociceptive, neuropathic and musculoskeletal origin. However, its efficiency is moderated and less adapted for low back pain. The experiments make it possible to estimate whether this modulated TENS method could improve existing anti-pain therapies, taking into account objective and subjective evaluation criteria. But this study must be followed by large population samples to answer all the problems of acute and chronic pains.


2021 ◽  
pp. 1151-1180
Author(s):  
Adrian Dashfield ◽  
David Kibblewhite

This chapter discusses the management of acute pain. It begins with an introduction which describes the benefits of acute pain management and the measurement of pain. Analgesic drugs are then described, including paracetamol; non-steroidal anti-inflammatory drugs (NSAIDs), and opioids (including their comparative efficacy). Patient-controlled analgesia (PCA), epidural analgesia, and continuous peripheral nerve blockade are described. Transcutaneous electrical nerve stimulation (TENS) and acupuncture are discussed. The management of the patient with persistent pain and a substance misuse disorder is also discussed. The chapter concludes with a discussion of non-opioid adjuvant analgesics.


2020 ◽  
pp. 096452842092119
Author(s):  
Xiaowei Shi ◽  
Wenjing Yu ◽  
Wei Zhang ◽  
Tong Wang ◽  
Oyunerdene Battulga ◽  
...  

Background To compare the effectiveness of electroacupuncture (EA) and transcutaneous electrical nerve stimulation (TENS) for pain control in knee osteoarthritis (KOA). Methods Four English (MEDLINE, EMBASE, Cochrane Library and Web of Science) and three Chinese (China Science Journal Citation Report (VIP), Wanfang and China National Knowledge Infrastructure (CNKI)) language databases were searched for eligible randomized controlled trials (RCTs), comparing four approaches: EA, TENS, medication and sham/placebo controls. The primary outcome was pain intensity, measured by visual analogue scale (VAS), numeric-rating scale (NRS) or Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale. Classic pairwise and Bayesian network meta-analyses were conducted to integrate the treatment efficacy/effectiveness through direct and indirect evidence. Results Thirteen studies were included. In the direct meta-analyses, there was no statistically significant overall effect of EA (mean difference (MD) −4.77, 95% confidence interval (CI) −12.51 to 2.96), while the overall effects of high-frequency transcutaneous electrical nerve stimulation (H-TENS) (MD −16.63, 95% CI −24.57 to −8.69) and medication (MD −7.12, 95% CI −12.07 to −2.17) were statistically significant. In the network meta-analyses, the relative effect of the EA and H-TENS groups (MD 5.07, 95% CI −11.33 to 21.93) on pain control did not differ. Meanwhile, H-TENS demonstrated the highest probability of being the first best treatment, and EA had the second highest probability. Conclusion The present analysis indicated that both EA and TENS exert significant pain relieving effects in KOA. Among the four treatments, H-TENS was found to be the optimal treatment choice for the management of KOA pain in the short-term, and EA the second best treatment option. Given that the application of TENS is recommended by various international guidelines for the treatment of KOA, EA may also represent a potentially effective non-pharmacologic therapy.


Pain ◽  
1984 ◽  
Vol 18 ◽  
pp. S68 ◽  
Author(s):  
S. P. Park ◽  
P. S. Thomas ◽  
L. Chen ◽  
H. A. Yuan ◽  
B. E. Frederiekson ◽  
...  

Author(s):  
S Jenifer Augustina ◽  
MG Kaviya ◽  
D Indrani

Background: Restless legs syndrome also known as Willis-Ekbom disease is a sensor motor disorder composed of an urge to move with or without associated discomfort that occurs with inactivity and improves with movement. The symptoms occur in leg muscles like calves and thighs. The feet and arms also affected and it causes the functional disability in pregnant women. Sleep disorder is typically the biggest complication of this condition. Unpleasant sensations are deep in the legs. Sensations appear during periods of rest or inactivity particularly in the evening and at night and relived by movement. Prevalence of RLS among pregnant women ranged from 10 to 34%. Aim: The aim of the study is to prove the effect of Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching and Exercises in restless leg syndrome among pregnant women. Objectives: To determine and prove the effectiveness of TENS with stretching to relive pain and improve the functional ability in restless leg syndrome among pregnant women. Materials and Methods: A Quasi-experimental study was conducted on 30 subjects using convenient sampling technique based on inclusion and exclusion criteria. Subjects were allotted into 2 groups i.e., Group A with 15 subjects and Group B with 15 subjects using odd even method of sampling. Experimental group will be treated with TENS and Stretching. Control group will be treated with exercises and massage. Result: Statistical Analysis of Post test for pain and functional performance revealed that patients who received Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching in Group A showed marked improvement compared to patients who received Massage and Exercises in Group B. Conclusion: From the result of the study it concluded that Transcutaneous Electrical Nerve Stimulation (TENS) with Stretching is more effective than massage and exercises in subjects with restless leg syndrome among pregnant women.


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