scholarly journals Stewart-Treves Syndrome in Obesity-Associated Chronic Lymphedema: A Case Report

2021 ◽  
Vol 12 (10) ◽  
pp. 395-399
Author(s):  
Michael J. Chaney ◽  
Xuanzhen Piao ◽  
Nayha Tahir ◽  
Grace W. Ying ◽  
Yetunde Omotosho ◽  
...  
Keyword(s):  
Case Report ◽  
Chronic Lymphedema

scholarly journals Elephantiasis nostra verrucosa associated with chronic lymphedema and acroangiodermatitis of mali (pseudo sarcoma of Kaposi). Case report

2020 ◽  
Vol 53 (3) ◽  
pp. 159-164
Author(s):  
Erika Patricia Scolari ◽  
Claudia María Barreto ◽  
Beatriz María Di Martino ◽  
Mirtha Rodríguez
Keyword(s):  
Case Report ◽  
Chronic Lymphedema

Chromosome 8 Polysomy Accounting for MYC Over-Expression in Angiosarcoma Arising as Somatic-Type Malignancy in Metastatic Teratoma. Case Report

2021 ◽  
pp. 106689692110677
Author(s):  
A. Cristina Vargas ◽  
Peter Grimison ◽  
Christopher Joy ◽  
Bernadette Garrone ◽  
Fiona Bonar ◽  
...  
Keyword(s):  
Case Report ◽  
Surrogate Marker ◽  
Chromosome 8 ◽  
High Grade ◽  
Clinical Scenario ◽  
Germ Cell Tumours ◽  
Over Expression ◽  
Post Irradiation ◽  
Chronic Lymphedema

MYC over-expression by immunohistochemistry (IHC) is utilised in routine pathology practice as a surrogate marker for MYC amplification, which plays a key oncogenic role in post-irradiation and chronic lymphedema-associated angiosarcoma. We present the case of a 32-year old male, who presented with high-grade angiosarcoma arising in a background of metastatic testicular teratoma. IHC for MYC showed strong nuclear expression in the angiosarcoma cells prompting the consideration of post-irradiation-induced angiosarcoma but our patient did not undergo radiotherapy. Fluorescence in-situ hybridization (FISH) excluded MYC amplification and instead showed Chromosome 8 polysomy, which accounted for the strong MYC IHC expression present, not previously described in the context of germ cell tumours. The occurrence of MYC over-expression due to polysomy illustrates a novel clinical scenario (angiosarcoma arising as somatic malignancy) where strong MYC IHC expression can be found in the absence of underlying amplification or prior radiotherapy exposure.

scholarly journals Angiosarcoma complicating lower leg elephantiasis in a male patient: An unusual clinical complication, case report and literature review

2018 ◽  
Vol 6 ◽  
pp. 2050313X1879634 ◽  
Author(s):  
Eran Shavit ◽  
Afsaneh Alavi ◽  
James J Limacher ◽  
R Gary Sibbald
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Lymph Node ◽  
Literature Review ◽  
Male Patient ◽  
Lower Leg ◽  
Breast Cancer Surgery ◽  
Diagnostic Biopsy ◽  
Multifocal Tumor ◽  
Chronic Lymphedema

Chronic lymphedema is rarely complicated by an angiosarcoma. Angiosarcoma superimposed on chronic lymphedema (Stewart–Treves syndrome) is usually seen post breast cancer surgery accompanied by lymph node resection of the axilla. This is a case report of a 59-year-old male patient with elephantiasis that developed an angiosarcoma of the lower leg. He died a month after the diagnostic biopsy was obtained. This is a rare multifocal tumor in a male with an unusual lower leg location. We reviewed the literature and the need to differentiate this often deadly lesion from a Kaposi’s sarcoma.

Squamous Cell Carcinoma in Chronic Lymphedema: Case Report and Review of the Literature

2002 ◽  
Vol 28 (10) ◽  
pp. 951-953 ◽  
Author(s):  
Hiroshi Furukawa ◽  
Yuhei Yamamoto ◽  
Hidehiko Minakawa ◽  
Tsuneki Sugihara
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Review Of The Literature ◽  
Chronic Lymphedema

scholarly journals Angiosarcoma of the Scalp: A Case Report

2022 ◽  
Vol 11 (2) ◽  
pp. 01-04
Author(s):  
Bekralas H
Keyword(s):  
Case Report ◽  
Tumor Progression ◽  
Beta Blockers ◽  
Histological Grade ◽  
Surgical Excision ◽  
Vascular Tumors ◽  
The Face ◽  
Mesodermal Origin ◽  
Chronic Lymphedema

Angiosarcomas also called hemangioendothelia, are rare and highly malignant vascular tumors of mesodermal origin, they represent 08-10% of cancers and can affect any part of the body.Angiosarcoma mainly affects the skin, the face is the preferred topography in adults, it remains exceptional in children, with a predilection for the mediastinum and pericardium,The angiogenesis of angiosarcomas is still poorly understood; However, chronic lymphedema and exposure to prolonged radiotherapy are blamed. Total surgical excision is the treatment of choice in localized forms, followed by chemotherapy. pre- and post-operative radiotherapy may be necessary.New studies have shown the effectiveness of beta blockers (propranolol) in the management of angiosarcomas.The prognosis depends on the age of the patient, the size of the tumor, the histological grade and the extent of tumor progression.

Hybrid Treatment Combining Lymphaticovenous Anastomoses and the Oriental Herbal Medicine Bofutsushosan for Obesity-Associated Lower Leg Elephantiasis Nostras Verrucosa: A Case Report

2020 ◽  
pp. 153473462093280
Author(s):  
Keisuke Shimbo ◽  
Yukako Okuhara ◽  
Kazunori Yokota
Keyword(s):  
Weight Loss ◽  
Case Report ◽  
Soft Tissue ◽  
Herbal Medicine ◽  
Venous Insufficiency ◽  
Lower Leg ◽  
Skin Changes ◽  
Hybrid Treatment ◽  
Dermatological Disease ◽  
Chronic Lymphedema

Elephantiasis nostras verrucosa (ENV) is a rare dermatological disease associated with chronic lymphedema caused by obesity, soft tissue infection, or chronic venous insufficiency. Although surgical debridement may be sufficient to treat the skin manifestations of ENV, treatment of ENV should focus on reducing lymph stasis to improve the skin changes and prevent recurrence. In this case report, we present the case of a 79-year-old woman who developed obesity-associated ENV in the lower leg. She was successfully treated by a combination of lymphaticovenous anastomoses and the oriental herbal medicine Bofutsushosan. To our knowledge, this is the first reported obesity-associated ENV case in which skin pathology was not only healed, but both edema relief and weight loss were successful. A treatment combining both surgery and the herbal medicine could be a potential therapeutic candidate for obesity-associated ENV.

Lymphangiosarcoma in a Chronic Lymphedematous Limb: A Case Report

1995 ◽  
Vol 81 (5) ◽  
pp. 381-382 ◽  
Author(s):  
Maria Victoria Lasa ◽  
Pedro Mateo ◽  
Natividad Bascón ◽  
José Baquedano ◽  
Fernando Fuertes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Primary Breast Cancer ◽  
Radical Mastectomy ◽  
Chronic Lymphedema

A 69-year-old-woman developed a lymphangiosarcoma of the limb on chronic lymphedema after radical mastectomy and radiotherapy for primary breast cancer 12 years before. Since 1948, when Stewart and Treves described this entity, 200 cases have been described. We report this case because of its extremely rare frequency. Concepts of etiology, treatment and prognosis are reviewed.

scholarly journals Squamous cell carcinoma arising from chronic lymphedema: case report and review of the literature

2010 ◽  
Vol 128 (1) ◽  
pp. 42-44 ◽  
Author(s):  
Carlos Augusto Gomes ◽  
Camila Beatriz Silva Magalhães ◽  
Cleber Soares Junior ◽  
Rodrigo de Oliveira Peixoto
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Case Reports ◽  
Cutaneous Lesion ◽  
Epidemiological Data ◽  
White Female ◽  
Histopathological Analysis ◽  
Chronic Lymphedema

CONTEXT: Squamous cell carcinoma arising from chronic lymphedema has only been reported in the literature 11 times (12 cases). Some aspects of its pathogenesis remain unclear and, for the first time, attention has been drawn to epidemiological data. CASE REPORT: A 90-year-old white female with chronic unilateral lower-limb lymphedema, secondary to trauma 20 years earlier, presented with a three-month history of a vegetating cutaneous lesion. There had not been any previous local ulceration. The tumor was completely excised and the histopathological analysis showed that it was an infiltrating squamous cell carcinoma. A literature review in the Medline (Medical Literature Analysis and Retrieval System Online) and Lilacs (Literatura Latino-Americana e do Caribe em Ciências da Saúde) databases using the MeSH (Medical Subject Heading) terms "Carcinoma, Squamous Cell" AND "Lymphedema" identified 112 references and found 12 similar case reports.

Misophonia: An Evidence-Based Case Report

2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Case History ◽  
Pure Tone ◽  
Physiological Responses ◽  
Evidence Based ◽  
Management Option ◽  
Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

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