Development of Bioimpedance Sensors and Measurement System for Biomedical In-Vitro Applications

2021 ◽  
Vol 7 (2) ◽  
pp. 496-499
Author(s):  
Stadler B. Eng. Sebastian ◽  
Herbert Plischke ◽  
Christian Hanshans

Abstract Bioimpedance analysis is a label-free and easy approach to obtain information on cellular barrier integrity and cell viability more broadly. In this work, we introduce a small, low-cost, portable in vitro impedance measurement system for studies where a shadow-free exposure of the cells is a requirement. It can be controlled by a user-friendly web interface and can perform measurements automated and autonomously at short intervals. The system can be integrated into an existing IoT network for remote monitoring and indepth analyses. A single-board computer (SBC) serves as the central unit, to control, analyze, store and forward the measurement data from the single-chip impedance analyzer. Various materials and manufacturing methods were used to produce a purpose-built lid on top of a modified 24-well microtiter plate in a “do it yourself” fashion. Furthermore, three different sensor designs were developed utilizing anodic aluminum oxide (AAO) membranes and gold-plated electrodes. Preliminary tests with potassium chloride (KCl) showed first promising results.

2010 ◽  
Vol 428-429 ◽  
pp. 487-492
Author(s):  
Xi Yin ◽  
Xiao Jun Wang ◽  
Yong Que Xie

This thesis introduces a low cost and high precision temperature cycle measurement system with adoption of PT100 as temperature sensor, with single chip computer as the core. The method of sub-three-wire connection is proposed for engineering practice, then, can eliminate the effects of lead wire resistance and simplify the external cable connection. We discuss and research circuit component selection, circuit design, improving system reliability, and a software method of piecewise linearization process is adopted, thus we ensure exact and reliable measure and the system characteristic of low cost and high precision.


2011 ◽  
Vol 365 ◽  
pp. 409-414
Author(s):  
Yi Lu ◽  
Cheng Yu Huo ◽  
Ai Jun He

Bioelectrical impedance measurement is a widely used biomedical detecting technology. However, most traditional bioelectrical impedance measurement devices are bulky, expensive and lack of flexibility. In order to reduce costs, increase flexibility and maintain similar performance, a portable bioelectrical impedance measurement system was designed in this paper. The measurement front, with an ARM based microcontroller and integrated impedance converter chip as its core device, communicated with the host computer via USB bus. Based on the four-electrode technique, DFT digital demodulation and software calibration and compensation algorithm, the system realized its functions. Experimental results indicate that the system can achieve high precision bioelectrical impedance measurement. With the advantage of high integration and low-cost, the system can be widely used in household healthcare, clinics and biomedical research and testing.


2014 ◽  
Vol 513-517 ◽  
pp. 4039-4042
Author(s):  
Cao Rui ◽  
Kong Jun Bao

This temperature measurement system is based on the control of AT89S52 single chip microcontroller, with temperature display function. Temperature information is changed into digital signal directly by a single bus digital temperature sensor DS18B20, and the digital signal is sent into microcontroller for real-time acquisition. The results are displayed through LCD module 1602 in real time. The system is with the characteristics of low cost, high precision, stable performance and convenient operation. The system can be extended to multi-point temperature detecting system easily, and adding temperature transfinite alarm function.


2020 ◽  
Author(s):  
Maximilian Stanglmayr ◽  
◽  
Maximilian Bäumler ◽  

Motorcyclists are among the most vulnerable road users in road traffic. Often, the cause of accidents is a loss of control on rural roads which could be averted by making use of the physical potential in terms of larger lean angles. At the same time, in reality driven lean angles over a larger group of riders and a longer route are unknown which is mainly due to the special measuring technology required. The focus is therefore on the development of a low-cost measurement method for measuring the lean angles of motorcycles. Smartphones are usually characterized by integrated inertial sensors, which are suitable for the acquisition of motorcycle driving dynamics. Employing a smartphone app tailored to the requirements for collecting measurement data on the motorcycle, the data of the sensors are recorded. During the offline evaluation, the rotation angles between the smartphone and the motorcycle coordinate system are determined, the inertial measurement data are transformed and the roll angle is calculated. An essential part is the alignment of the developed measurement chain with a high-precision measurement system. This was carried out on different routes and thus the data quality was determined. As a feasibility study, a test person study with several participants was carried out, which confirmed the practical suitability of the measurement chain. Hence, the study outcomes are briefly shown and discussed. The successful validation on different routes, the practical suitability of the data acquisition and the accuracy of the measurement system encourage to roll out the smartphone app to a larger panel of test persons and thus to collect data on a larger driver collective.


2011 ◽  
Vol 383-390 ◽  
pp. 5166-5170
Author(s):  
Ming Lin Yao ◽  
Yu Jun Guan ◽  
Cui Ying Dong

In the ultrasonic gas temperature measurement system, the principle is that the velocity of sound in gas is a function of temperature. But because the propagation speed of ultrasonic wave can be easily affected by humidity, the accuracy of the gas temperature measurement will be affected too. This dissertation will implement the ultrasonic gas temperature measurement system with humidity correction suitable for all kinds of environment humidity. This type of ultrasonic technique is a highly efficient algorithm with the advantages of both time-of-flight method and phase shift method. And the system is realized with a single-chip microcomputer-based with a relative humidity/water vapor pressure meter. The main advantages of this ultrasonic temperature measurement system are high resolution, using narrow-bandwidth ultrasonic transducer of low cost and ease of implementation.


2019 ◽  
Vol 9 (02) ◽  
pp. 63-67
Author(s):  
Indra Feriadi ◽  
Fajar Aswin ◽  
M Iqbal Nugraha

Vibration measurement technology using conventional sensors such as piezoelectric (PZT) Accelerometer is still expensive. Currently, many low-cost vibration measuring devices have been developed by using Micro Electro Mechanical System (MEMS) technology. This study aims to analyze the results of vibration measurement system MEMS Accelerometer ADXL345 with PZT Accelerometer. This research applies design and develop approach with comparative data analysis technique, that is comparing data of result of measurement of MEMS Accelerometer ADXL345 to PZT Accelerometer Vibroport80. The construction comprises the ADXL345 sensor connected to the Arduino Mega 2560 microcontroller operated by Widows operating system and programming language Arduino IDE 1.08. Testing of measurements at Bearing speeds of 500, 1000, and 1500 RPM with length of time measurements at 5, 10, and 20 seconds respectively. The analysis of the test results shows that the MEMS Accelerometer ADXL345 of vibration measurement system can measure, process and display vibration measurement data larger 3% than PZT Accelerometer and can provide the best measurement accuracy at 20 seconds measurement length of time.


2018 ◽  
Vol 12 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Il-Hwan Park ◽  
Yeonhee Hong ◽  
Hee-Sook Jun ◽  
Eou-Sik Cho ◽  
Sungbo Cho

Micromachines ◽  
2020 ◽  
Vol 11 (5) ◽  
pp. 479
Author(s):  
Anthony Beck ◽  
Franziska Obst ◽  
Mathias Busek ◽  
Stefan Grünzner ◽  
Philipp Mehner ◽  
...  

The interest in large-scale integrated (LSI) microfluidic systems that perform high-throughput biological and chemical laboratory investigations on a single chip is steadily growing. Such highly integrated Labs-on-a-Chip (LoC) provide fast analysis, high functionality, outstanding reproducibility at low cost per sample, and small demand of reagents. One LoC platform technology capable of LSI relies on specific intrinsically active polymers, the so-called stimuli-responsive hydrogels. Analogous to microelectronics, the active components of the chips can be realized by photolithographic micro-patterning of functional layers. The miniaturization potential and the integration degree of the microfluidic circuits depend on the capability of the photolithographic process to pattern hydrogel layers with high resolution, and they typically require expensive cleanroom equipment. Here, we propose, compare, and discuss a cost-efficient do-it-yourself (DIY) photolithographic set-up suitable to micro-pattern hydrogel-layers with a resolution as needed for very large-scale integrated (VLSI) microfluidics. The achievable structure dimensions are in the lower micrometer scale, down to a feature size of 20 µm with aspect ratios of 1:5 and maximum integration densities of 20,000 hydrogel patterns per cm². Furthermore, we demonstrate the effects of miniaturization on the efficiency of a hydrogel-based microreactor system by increasing the surface area to volume (SA:V) ratio of integrated bioactive hydrogels. We then determine and discuss a correlation between ultraviolet (UV) exposure time, cross-linking density of polymers, and the degree of immobilization of bioactive components.


2013 ◽  
Vol 838-841 ◽  
pp. 2174-2178
Author(s):  
Mo Yang ◽  
Nalin Warnajith ◽  
Atsushi Minato ◽  
Satoru Ozawa

Monitoring of inclination of land is important to prevent damage from landslide. Low cost and stable system is necessary for this purpose. This paper presents a new inclination measurement system and its application to sensor network of disaster prevention. Our system has a bull's eye level, a digital camera and wireless module. The angle and direction of inclination is measured from the photo of bull's eye level. The achieved resolution was 0.0053degree/pixel using a bull's eye level with a curvature radius of 800 mm. Measurement data was compared with the data from commercial inclinometer.


2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A80.3-A81
Author(s):  
Seunghon Ham ◽  
Seong-Kyu Kang

The Internet of Things (IoT) is an important keyword in the Fourth Industrial Revolution. IoT is expected to have a massive impact for human being, but these are still early days. IoT enables these objects to collect and exchange data through the wireless network, such as devices, vehicles, buildings, and other items that include electronic devices, software, sensors, and network connections. IoT is a technology that can be used and expanded in various applications such as industrial, manufacturing, medical and consumer products and so on. This research focuses specifically on the development of measurement systems for particulate matter using IoT technology for occupational as well as environmental settings. Currently, the government is providing the concentration of particulate matter (PM2.5/10) hourly. However, it is difficult to reflect personal exposure because it is installed on the top of a building. Therefore, this study shows development of the particulate matter measuring system using IoT and obtains the personal measurement data of the particulate matter. Also, to provide a further insight, we will also present how particulate matter measurement system works by showing some measurements collected with an experimental testbed deployed in our research group. Still, it is necessary to improve the quality of system and the convergence between pollutant measurement including particulate matter and IoT can provide new opportunities for occupational and environmental particulate matter measurement system.AcknowledgementThis work was supported by Gachon University research fund of 2018(GCU-2018–5259) and the National Research Foundation of Korea (NRF) grant funded by the Korea government (Ministry of Science, ICT) (No. NRF-2017R1C1B1002717).


Sign in / Sign up

Export Citation Format

Share Document